| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cholangitis, Sclerosing | D015209 | 1 associated lipids |
| Hepatic Insufficiency | D048550 | 1 associated lipids |
| Lung Abscess | D008169 | 1 associated lipids |
| Central Nervous System Viral Diseases | D020805 | 1 associated lipids |
| Facial Nerve Injuries | D020220 | 1 associated lipids |
| Intertrigo | D007402 | 1 associated lipids |
| Miller Fisher Syndrome | D019846 | 1 associated lipids |
| Mediastinal Emphysema | D008478 | 1 associated lipids |
| Angiolymphoid Hyperplasia with Eosinophilia | D000796 | 1 associated lipids |
| Eye Infections, Viral | D015828 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hatanaka H and Shimomura K | [Immunosuppressive activity of a microbial product]. | 1997 | Nippon Yakurigaku Zasshi | pmid:9503409 |
| Milićević NM and Milićević Z | Stereological study of splenic tissue compartments in FK506-treated rats. | 1997 | Histol. Histopathol. | pmid:9302561 |
| Wingard JR et al. | Lack of interaction between tacrolimus (FK506) and methotrexate in bone marrow transplant recipients. | 1997 | Bone Marrow Transplant. | pmid:9232256 |
| Yamagami S et al. | Mechanism of concordant corneal xenograft rejection in mice: synergistic effects of anti-leukocyte function-associated antigen-1 monoclonal antibody and FK506. | 1997 | Transplantation | pmid:9233699 |
| Wijnen RM and Ericzon BG | Update of tacrolimus in pancreas transplantation. | 1997 | Diabet. Med. | pmid:9400914 |
| Sawabe T et al. | Sinus arrest during tacrolimus (FK506) and digitalis treatment in a bone marrow transplant recipient. | 1997 | Transplantation | pmid:9233725 |
| Misao T et al. | Efficacy of combining donor-specific presensitization with a simultaneous single injection of tacrolimus on pulmonary allografts. | 1997 | J. Heart Lung Transplant. | pmid:9402508 |
| Suzuki J et al. | Inhibition of accelerated coronary atherosclerosis with short-term blockade of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-1 in a heterotopic murine model of heart transplantation. | 1997 | J. Heart Lung Transplant. | pmid:9402514 |
| Cohen SB et al. | Autocrine and paracrine regulation of human T cell IL-10 production. | 1997 | J. Immunol. | pmid:9190906 |
| Zucker K et al. | Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings. | 1997 | Transpl. Immunol. | pmid:9402690 |
| Miyata Y et al. | Phosphorylation of the immunosuppressant FK506-binding protein FKBP52 by casein kinase II: regulation of HSP90-binding activity of FKBP52. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9405642 |
| Taylor DO | The use of tacrolimus and mycophenolate mofetil after cardiac transplantation. | 1997 | Curr. Opin. Cardiol. | pmid:9192485 |
| Harihara Y and Makuuchi M | [Partial liver transplantation]. | 1997 | Nippon Naika Gakkai Zasshi | pmid:9340350 |
| Hayashi S et al. | Adenovirus-mediated gene transfer to the xenogeneic liver in liver xenotransplantation: the transduction of complement regulatory factor genes (DAF and HRF20). | 1997 | Transplant. Proc. | pmid:9193595 |
| Wallemacq PE et al. | IMx tacrolimus II vs IMx tacrolimus microparticle enzyme immunoassay evaluated in renal and hepatic transplant patients. | 1997 | Clin. Chem. | pmid:9342026 |
| Hohage H et al. | Effects of cyclosporin A and FK 506 on lipid metabolism and fibrinogen in kidney transplant recipients. | 1997 | Clin Transplant | pmid:9193847 |
| Gold BG et al. | A nonimmunosuppressant FKBP-12 ligand increases nerve regeneration. | 1997 | Exp. Neurol. | pmid:9344552 |
| de Paulis A et al. | Human synovial mast cells. II. Heterogeneity of the pharmacologic effects of antiinflammatory and immunosuppressive drugs. | 1997 | Arthritis Rheum. | pmid:9082935 |
| Moroda T et al. | Self-reactive forbidden clones are confined to pathways of intermediate T-cell receptor cell differentiation even under immunosuppressive conditions. | 1997 | Immunology | pmid:9203970 |
| Spencer CM et al. | Tacrolimus. An update of its pharmacology and clinical efficacy in the management of organ transplantation. | 1997 | Drugs | pmid:9421697 |
| Mrvos R et al. | Tacrolimus (FK 506) overdose: a report of five cases. | 1997 | J. Toxicol. Clin. Toxicol. | pmid:9204100 |
| Stegall MD et al. | Mycophenolate mofetil decreases rejection in simultaneous pancreas-kidney transplantation when combined with tacrolimus or cyclosporine. | 1997 | Transplantation | pmid:9422404 |
| Sikorski R and Peters R | A cell growth switch. | 1997 | Science | pmid:9206844 |
| Shield CF et al. | Assessment of health-related quality of life in kidney transplant patients receiving tacrolimus (FK506)-based versus cyclosporine-based immunosuppression. FK506 Kidney Transplant Study Group. | 1997 | Transplantation | pmid:9422413 |
| Shafiee A et al. | Chemical and biological characterization of two FK506 analogs produced by targeted gene disruption in Streptomyces sp. MA6548. | 1997 | J. Antibiot. | pmid:9207912 |
| Stegall MD et al. | Prednisone withdrawal 14 days after liver transplantation with mycophenolate: a prospective trial of cyclosporine and tacrolimus. | 1997 | Transplantation | pmid:9422416 |
| Uberti JP et al. | Tacrolimus and methotrexate for the prophylaxis of acute graft-versus-host disease in allogeneic bone marrow transplantation in patients with hematologic malignancies. | 1997 | Bone Marrow Transplant. | pmid:9208118 |
| Shihab FS et al. | Mechanism of fibrosis in experimental tacrolimus nephrotoxicity. | 1997 | Transplantation | pmid:9422427 |
| Ohashi Y et al. | Successful treatment of steroid-resistant severe acute GVHD with 24-h continuous infusion of FK506. | 1997 | Bone Marrow Transplant. | pmid:9085743 |
| Vu MD et al. | Tacrolimus (FK506) and sirolimus (rapamycin) in combination are not antagonistic but produce extended graft survival in cardiac transplantation in the rat. | 1997 | Transplantation | pmid:9422432 |
| Oz HS and Hughes WT | Novel anti-Pneumocystis carinii effects of the immunosuppressant mycophenolate mofetil in contrast to provocative effects of tacrolimus, sirolimus, and dexamethasone. | 1997 | J. Infect. Dis. | pmid:9086147 |
| Wagner K et al. | New-onset diabetes mellitus in pediatric thoracic organ recipients receiving tacrolimus-based immunosuppression. | 1997 | J. Heart Lung Transplant. | pmid:9087870 |
| Yasutomi M et al. | Evaluation of tetrahydropyranyladriamycin as an immunosuppressant in concordant xenotransplantation. | 1997 | J. Heart Lung Transplant. | pmid:9087871 |
| Kitagaki K et al. | Facilitation of apoptosis by cyclosporins A and H, but not FK506 in mouse bronchial eosinophils. | 1997 | Eur. J. Pharmacol. | pmid:9430427 |
| Morrissey PE et al. | Correlation of clinical outcomes after tacrolimus conversion for resistant kidney rejection or cyclosporine toxicity with pathologic staging by the Banff criteria. | 1997 | Transplantation | pmid:9089224 |
| Midtvedt K et al. | Successful pregnancies in a combined pancreas and renal allograft recipient and in a renal graft recipient on tacrolimus treatment. | 1997 | Nephrol. Dial. Transplant. | pmid:9430893 |
| Kiuchi T et al. | A hepatic graft tuberculosis transmitted from a living-related donor. | 1997 | Transplantation | pmid:9089234 |
| Paterson DL and Singh N | Interactions between tacrolimus and antimicrobial agents. | 1997 | Clin. Infect. Dis. | pmid:9431391 |
| Steffen R et al. | Autoimmune enteropathy in a pediatric patient: partial response to tacrolimus therapy. | 1997 | Clin Pediatr (Phila) | pmid:9152557 |
| Chow FS et al. | Effect of hematocrit and albumin concentration on hepatic clearance of tacrolimus (FK506) during rabbit liver perfusion. | 1997 | Drug Metab. Dispos. | pmid:9152601 |
| Woo M et al. | Toxicities of tacrolimus and cyclosporin A after allogeneic blood stem cell transplantation. | 1997 | Bone Marrow Transplant. | pmid:9466284 |
| Araki T et al. | Effects of vinconate on age-related alterations in [3H]MK-801, [3H]glycine, sodium-dependent D-[3H]aspartate, [3H]FK-506 and [3H]PN200-110 binding in rats. | 1997 | Mech. Ageing Dev. | pmid:9152958 |
| Banholzer R et al. | Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3' untranslated region. | 1997 | Mol. Cell. Biol. | pmid:9154824 |
| Delehanty LL et al. | Apoptosis in a Fas-resistant, T-cell receptor-sensitive human leukaemic T-cell clone. | 1997 | Immunology | pmid:9155645 |
| Newell KA et al. | Treatment with either anti-CD4 or anti-CD8 monoclonal antibodies blocks alphabeta T cell-mediated rejection of intestinal allografts in mice. | 1997 | Transplantation | pmid:9381541 |
| Iyengar AR et al. | Striking augmentation of hematopoietic cell chimerism in noncytoablated allogeneic bone marrow recipients by FLT3 ligand and tacrolimus. | 1997 | Transplantation | pmid:9158008 |
| van Hooff JP | Pneumocystis carinii pneumonia after renal transplantation. | 1997 | Transplantation | pmid:9158038 |
| Siddiqui MA et al. | Lymphomatoid papulosis and FK 506. | 1997 | Int. J. Dermatol. | pmid:9159004 |
| Okudaira H et al. | Control of allergic diseases by regulation of cytokine gene transcription. | 1997 | Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf A M | pmid:9383912 |
| Lee JW et al. | Tacrolimus (FK506): validation of a sensitive enzyme-linked immunosorbent assay kit for and application to a clinical pharmacokinetic study. | 1997 | Ther Drug Monit | pmid:9108651 |
| Thyagarajan GK et al. | FK506-induced fulminant leukoencephalopathy after single-lung transplantation. | 1997 | Ann. Thorac. Surg. | pmid:9386723 |
| Hickman PE et al. | Clinical chemistry and post-liver-transplant monitoring. | 1997 | Clin. Chem. | pmid:9265907 |
| Tomás ML | [Immunosuppressive agents: side effects]. | 1997 | An R Acad Nac Med (Madr) | pmid:9616947 |
| Aicher L et al. | Decrease in kidney calbindin-D 28kDa as a possible mechanism mediating cyclosporine A- and FK-506-induced calciuria and tubular mineralization. | 1997 | Biochem. Pharmacol. | pmid:9113092 |
| Paterson DL et al. | Could a herpesvirus mimic tacrolimus-induced leukoencephalopathy? | 1997 | Ann. Neurol. | pmid:9266742 |
| Ahsan N et al. | Successful reversal of acute vascular rejection in a renal allograft with combined mycophenolate mofetil and tacrolimus as primary immunotherapy. | 1997 | Clin Transplant | pmid:9113443 |
| Yoshimoto T et al. | [Leukoencephalopathy probably caused by tacrolimus hydrate after stem cell transplantation in a girl with MDS 7 monosomy]. | 1997 | Rinsho Ketsueki | pmid:9267167 |
| Singh N et al. | Invasive fungal infections in liver transplant recipients receiving tacrolimus as the primary immunosuppressive agent. | 1997 | Clin. Infect. Dis. | pmid:9114144 |
| Woodle ES et al. | Reversal of accelerated renal allograft rejection with FK 506. | 1997 | Clin Transplant | pmid:9267710 |
| Eum SY et al. | Inhibition by the immunosuppressive agent FK-506 of antigen-induced airways eosinophilia and bronchial hyperreactivity in mice. | 1997 | Br. J. Pharmacol. | pmid:9117088 |
| Ahsan N et al. | Pure red cell aplasia due to parvovirus B19 infection in solid organ transplantation. | 1997 | Clin Transplant | pmid:9267713 |
| Jacobson PA et al. | Stability of tacrolimus in an extemporaneously compounded oral liquid. | 1997 | Am J Health Syst Pharm | pmid:9117806 |
| Singh N et al. | Bloodstream infections in liver transplant recipients receiving tacrolimus. | 1997 | Clin Transplant | pmid:9267715 |
| Guo Z et al. | In vivo effects of leflunomide on normal pancreatic islet and syngeneic islet graft function. | 1997 | Transplantation | pmid:9075844 |
| Gruessner RW | Tacrolimus in pancreas transplantation: a multicenter analysis. Tacrolimus Pancreas Transplant Study Group. | 1997 | Clin Transplant | pmid:9267719 |
| Ciancio G et al. | Use of intravenous FK506 to treat acute rejection in simultaneous pancreas-kidney transplant recipients on maintenance oral FK506. | 1997 | Transplantation | pmid:9075856 |
| Sherrington PD et al. | TLiSA1 (PTA1) activation antigen implicated in T cell differentiation and platelet activation is a member of the immunoglobulin superfamily exhibiting distinctive regulation of expression. | 1997 | J. Biol. Chem. | pmid:9268302 |
| Mirza DF et al. | Reduced acute rejection after liver transplantation with Neoral-based triple immunosuppression. | 1997 | Lancet | pmid:9078209 |
| Danovitch GM | Cyclosporin or tacrolimus: which agent to choose? | 1997 | Nephrol. Dial. Transplant. | pmid:9269630 |
| Yoshikawa H et al. | FK506 prevents induction of rat experimental autoimmune myasthenia gravis. | 1997 | J. Autoimmun. | pmid:9080295 |
| Talbot D et al. | Alopecia as a consequence of tacrolimus therapy in renal transplantation? | 1997 | Transplantation | pmid:9415574 |
| Nagai H et al. | FK-506 and cyclosporin A potentiate the IgE antibody production by contact sensitization with hapten in mice. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9336339 |
| Seifeldin RA et al. | Nifedipine interaction with tacrolimus in liver transplant recipients. | 1997 | Ann Pharmacother | pmid:9161650 |
| Homey B et al. | A local lymph node assay to analyse immunosuppressive effects of topically applied drugs. | 1997 | Eur. J. Pharmacol. | pmid:9163567 |
| Klupp J et al. | Mycophenolate mofetil added to immunosuppression after liver transplantation--first results. | 1997 | Transpl. Int. | pmid:9163864 |
| McKee M et al. | Initial experience with FK506 (tacrolimus) in pediatric renal transplant recipients. | 1997 | J. Pediatr. Surg. | pmid:9165452 |
| Uno T et al. | The pharmacokinetics of water-in-oil-in-water-type multiple emulsion of a new tacrolimus formulation. | 1997 | Lipids | pmid:9168461 |
| Jiang H et al. | Distinct tissue and cellular distribution of two major isoforms of calcineurin. | 1997 | Mol. Immunol. | pmid:9393969 |
| Schweda F et al. | Tacrolimus treatment for steroid- and cyclosporin-resistant minimal-change nephrotic syndrome. | 1997 | Nephrol. Dial. Transplant. | pmid:9394341 |
| Sabatini DM et al. | Neural roles of immunophilins and their ligands. | 1997 | Mol. Neurobiol. | pmid:9396011 |
| Ballantyne CM et al. | Pathophysiology and treatment of lipid perturbation after cardiac transplantation. | 1997 | Curr. Opin. Cardiol. | pmid:9192484 |
| Gruessner RW and Sharp HL | Living-related intestinal transplantation: first report of a standardized surgical technique. | 1997 | Transplantation | pmid:9415566 |
| Ilan Y et al. | Transient immunosuppression with FK506 permits long-term expression of therapeutic genes introduced into the liver using recombinant adenoviruses in the rat. | 1997 | Hepatology | pmid:9328318 |
| Vella JP and Sayegh MH | Maintenance pharmacological immunosuppressive strategies in renal transplantation. | 1997 | Postgrad Med J | pmid:9338020 |
| Gruessner AC and Sutherland DE | Pancreas transplants for United States (US) and non-US cases as reported to the International Pancreas Transplant Registry (IPTR) and to the United Network for Organ Sharing (UNOS). | 1997 | Clin Transpl | pmid:9919390 |
| Odorico JS et al. | Advances in pancreas transplantation: the University of Wisconsin experience. | 1997 | Clin Transpl | pmid:9919400 |
| Katznelson S et al. | Clinical aspects of sensitization. | 1997 | Clin Transpl | pmid:9919412 |
| Nair SC et al. | Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor. | 1997 | Mol. Cell. Biol. | pmid:9001212 |
| Pirenne J et al. | Donor-specific unmodified bone marrow transfusion does not facilitate intestinal engraftment after bowel transplantation in a porcine model. | 1997 | Surgery | pmid:9001555 |
| Felldin M et al. | Rescue therapy with tacrolimus (FK 506) in renal transplant recipients--a Scandinavian multicenter analysis. | 1997 | Transpl. Int. | pmid:9002146 |
| Becker G et al. | Rescue therapy with tacrolimus in simultaneous pancreas/kidney transplantation. | 1997 | Transpl. Int. | pmid:9002152 |
| Odom A et al. | The immunosuppressant FK506 and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein. | 1997 | Antimicrob. Agents Chemother. | pmid:8980772 |
| Tsamandas AC et al. | Adult heart transplantation under tacrolimus (FK506) immunosuppression: histopathologic observations and comparison to a cyclosporine-based regimen with lympholytic (ATG) induction. | 1997 | J. Heart Lung Transplant. | pmid:9257254 |
| Trede NS et al. | Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation. | 1997 | Bone Marrow Transplant. | pmid:9257897 |
| Freiberg RA et al. | Transcriptional control in keratinocytes and fibroblasts using synthetic ligands. | 1997 | J. Clin. Invest. | pmid:9169490 |
| Wang JH and Kelly PT | Postsynaptic calcineurin activity downregulates synaptic transmission by weakening intracellular Ca2+ signaling mechanisms in hippocampal CA1 neurons. | 1997 | J. Neurosci. | pmid:9169521 |
| Dodd DA | Rapid resolution of gingival hyperplasia after switching from cyclosporine A to tacrolimus. | 1997 | J. Heart Lung Transplant. | pmid:9171281 |
| Savoldi E et al. | [Dental and oral aspects in pediatric liver transplant patients. A comparison between the effects of cyclosporine A and FK 506]. | 1997 | Minerva Stomatol | pmid:9173223 |
| Rezeig MA et al. | Kaposi's sarcoma in liver transplant recipients on FK506: two case reports. | 1997 | Transplantation | pmid:9175820 |
| Aoki Y and Kao PN | Cyclosporin A-sensitive calcium signaling represses NFkappaB activation in human bronchial epithelial cells and enhances NFkappaB activation in Jurkat T-cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9177287 |