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Mean field analysis of FKBP12 complexes with FK506 and rapamycin: implications for a role of crystallographic water molecules in molecular recognition and specificity. |
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Biosynthesis of the shikimate-derived starter unit of the immunosuppressant ascomycin: stereochemistry of the 1,4-conjugate elimination. |
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Clin Transplant |
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Transplantation |
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Transplantation |
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Proc. Natl. Acad. Sci. U.S.A. |
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Proc. Natl. Acad. Sci. U.S.A. |
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Transplantation |
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Influences of immunosuppressive agents, FK506 and cyclosporin on systemic Candida albicans infection in mice. |
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Mycopathologia |
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Cancer |
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Transplantation |
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Transplantation |
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Transplant. Proc. |
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FK506 and the role of immunophilins in nerve regeneration. |
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Mol. Neurobiol. |
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Clinically significant drug interactions with new immunosuppressive agents. |
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Drug Saf |
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Cell Calcium |
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Enhanced expression of cytokine-induced neutrophil chemoattractant in rat hepatic allografts during acute rejection. |
1997 |
Hepatology |
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Discovery of less nephrotoxic FK506 analogs and determining immunophilin dependence of immunosuppressant nephrotoxicity with a novel single-dose rat cisplatin potentiation assay. |
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J. Pharmacol. Exp. Ther. |
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Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center. |
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Biochemistry |
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Identification of a 37 kDa tacrolimus, sirolimus and cyclosporine binding immunophilin possessing glyceraldehyde 3-phosphate dehydrogenase activity isolated from the Jurkat T cell line. |
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Invasive aspergillosis in mice immunosuppressed with cyclosporin A, tacrolimus (FK506), or sirolimus (rapamycin). |
1997 |
J. Infect. Dis. |
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Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS. |
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Transplantation |
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1997 |
Transplantation |
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Asialoglycoprotein/asialoglycoprotein receptor (AGP-AGPr) interaction is an important mechanism for the uptake of FK506 by hepatocytes. |
1997 |
Transplantation |
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Modeling the interaction between FK506 and FKBP12: a mechanism for formation of the calcineurin inhibitory complex. |
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Metabolism of tacrolimus (FK 506) in rat liver microsomes. Effect of rifampin and dexamethasone. |
1997 |
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1997 |
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Comparison of cyclosporine A and FK506 with regard to complaints and psychosocial characteristics before and after liver transplantation. |
1997 |
Transplant. Proc. |
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Three-year follow-up of the European Multicenter Tacrolimus (FK506) Liver Study. |
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1997 |
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Multicenter randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of renal allograft rejection: a report of the European Tacrolimus Multicenter Renal Study Group. |
1997 |
Transplantation |
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