Strasser S et al. |
Effect of FK506 on insulin secretion in normal dogs. |
1992 |
Metab. Clin. Exp. |
pmid:1371575
|
Andersson J et al. |
FK 506 and cyclosporine inhibit antigen- or mitogen-induced monokine and lymphokine production in vitro. |
1992 |
Transplant. Proc. |
pmid:1371621
|
Matsuura T et al. |
Blockade of interleukin-2 production from cloned T cells by cyclosporine and FK 506 assessed by proliferation assays in vitro. |
1992 |
Transplant. Proc. |
pmid:1371623
|
Okamura N et al. |
Enhanced liver regeneration by FK 506 can be blocked by interleukin-1 alpha and interleukin-2. |
1992 |
Transplant. Proc. |
pmid:1371624
|
Sakr M et al. |
Effect of renal ischemia on plasma levels of FK 506 in rats. |
1992 |
Transplant. Proc. |
pmid:1371625
|
Kusne S et al. |
Infections during a randomized trial comparing cyclosporine to FK 506 immunosuppression in liver transplantation. |
1992 |
Transplant. Proc. |
pmid:1371626
|
Lee C et al. |
FK-506 binding protein from Tolypocladium inflatum: resistance of FKBP/FK-506 complex against proteolysis. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1371677
|
Edkins RD et al. |
Comparison of cyclosporine and FK506 effects on glutathione levels in rat cochlea, brain, liver and kidney. |
1992 |
Biochem. Pharmacol. |
pmid:1371687
|
Galat A et al. |
A rapamycin-selective 25-kDa immunophilin. |
1992 |
Biochemistry |
pmid:1371698
|
Höllsberg P et al. |
Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells. |
1992 |
J. Immunol. |
pmid:1374452
|
Schreiber SL and Crabtree GR |
The mechanism of action of cyclosporin A and FK506. |
1992 |
Immunol. Today |
pmid:1374612
|
Demetris AJ et al. |
Conversion of liver allograft recipients from cyclosporine to FK506 immunosuppressive therapy--a clinicopathologic study of 96 patients. |
1992 |
Transplantation |
pmid:1374944
|
Bundick RV et al. |
FK506 as an agonist to induce inhibition of interleukin 2 production. |
1992 |
Transplantation |
pmid:1374947
|
Sakr M et al. |
The protective effect of FK506 pretreatment against renal ischemia/reperfusion injury in rats. |
1992 |
Transplantation |
pmid:1374948
|
Lepre CA et al. |
Solution structure of FK506 bound to FKBP-12. |
1992 |
FEBS Lett. |
pmid:1375171
|
Ruff VA et al. |
FKBP-12 is not an inhibitor of protein kinase C. |
1992 |
Immunol. Invest. |
pmid:1375189
|
Kawaguchi S |
[Effects of FK506 on aminonucleoside-induced nephrotic rats]. |
1992 |
Nihon Jinzo Gakkai Shi |
pmid:1375300
|
Jain A et al. |
Intravenous, oral pharmacokinetics, and oral dosing of FK 506 in small bowel transplant patients. |
1992 |
Transplant. Proc. |
pmid:1376518
|
Masutani H et al. |
Suppression of the histologic changes of GVHD by FK 506 in rat small bowel transplantation. |
1992 |
Transplant. Proc. |
pmid:1376519
|
Santiago SF et al. |
Effect of short-term immunosuppressive therapy with FK 506 or CyA on the donor in small intestine allotransplantation in rats. |
1992 |
Transplant. Proc. |
pmid:1376520
|
Utsunomiya H et al. |
Effect of FK 506 on orthotopic small bowel transplantation in rats. |
1992 |
Transplant. Proc. |
pmid:1376521
|
Yagihashi A et al. |
Changes in cell surface markers in human small bowel transplantation with FK 506. |
1992 |
Transplant. Proc. |
pmid:1376522
|
Abu-Elmagd K et al. |
Management of intestinal transplantation in humans. |
1992 |
Transplant. Proc. |
pmid:1376523
|
Takaori K et al. |
Basic study on immunologic effects of cyclosporine and FK 506 for application to pancreatic transplantation. |
1992 |
Transplant. Proc. |
pmid:1376531
|
Ohtsuka S et al. |
The effect of short-term FK 506 therapy on pancreas transplantation using the cuff technique in rats. |
1992 |
Transplant. Proc. |
pmid:1376532
|
Lemster B et al. |
Cytokine gene expression in murine lymphocytes activated in the presence of FK 506, bredinin, mycophenolic acid, or brequinar sodium. |
1992 |
Transplant. Proc. |
pmid:1281576
|
Tze WJ et al. |
FK 506: an effective immunosuppressant for islet xenotransplantation. |
1992 |
Transplant. Proc. |
pmid:1281577
|
Kamei T et al. |
Established intraportal islet allograft is rejected despite the acceptance of donor-specific second cardiac allograft. |
1992 |
Transplant. Proc. |
pmid:1281579
|
Woo J et al. |
FK 506 treatment following syngeneic bone marrow transplantation does not inhibit clonal deletion of V beta 5+ or V beta 11+ T cells. |
1992 |
Transplant. Proc. |
pmid:1281583
|
Souza ER et al. |
Acute effects of FK 506 on glomerular hemodynamics. |
1992 |
Transplant. Proc. |
pmid:1281585
|
Hanke JH et al. |
FK506 and rapamycin selectively enhance degradation of IL-2 and GM-CSF mRNA. |
1992 |
Lymphokine Cytokine Res. |
pmid:1281674
|
Logan TM et al. |
Side chain and backbone assignments in isotopically labeled proteins from two heteronuclear triple resonance experiments. |
1992 |
FEBS Lett. |
pmid:1281793
|
Bergstrand H et al. |
Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1281879
|
Rondeau E |
[Mechanism of action of the new immunosuppressants: cyclosporin A, FK 506 and rapamycin]. |
1992 |
Nephrologie |
pmid:1379348
|
Schreiber SL |
Immunophilin-sensitive protein phosphatase action in cell signaling pathways. |
1992 |
Cell |
pmid:1379518
|
Aldape RA et al. |
Charged surface residues of FKBP12 participate in formation of the FKBP12-FK506-calcineurin complex. |
1992 |
J. Biol. Chem. |
pmid:1379588
|
Langrehr JM et al. |
Nitric oxide production in host-versus-graft and graft-versus-host reactions in the rat. |
1992 |
J. Clin. Invest. |
pmid:1379617
|
Kumano K et al. |
[Functional and morphological changes in rat kidney induced by FK506 and its reversal by various vasodilators]. |
1992 |
Nippon Hinyokika Gakkai Zasshi |
pmid:1379657
|
Woodle ES et al. |
FK506: inhibition of humoral mechanisms of hepatic allograft rejection. |
1992 |
Transplantation |
pmid:1379749
|
Sato K et al. |
Effectiveness of triple drug immunosuppression for pancreaticoduodenal allotransplantation in dogs. |
1992 |
Transplant. Proc. |
pmid:1379753
|
Kobayashi N et al. |
Abdominal organ cluster transplantation in pigs receiving FK 506. |
1992 |
Transplant. Proc. |
pmid:1379754
|
Petros AM et al. |
Conformation of two non-immunosuppressive FK506 analogs when bound to FKBP by isotope-filtered NMR. |
1992 |
FEBS Lett. |
pmid:1380470
|
Van Thiel DH et al. |
FK 506 reduces the injury experienced following renal ischemia and reperfusion. |
1992 |
Ren Fail |
pmid:1380720
|
Bolton C |
The efficacy of cyclosporin A, FK-506 and prednisolone to modify the adoptive transfer of experimental allergic encephalomyelitis (EAE). |
1992 |
Agents Actions |
pmid:1380765
|
Terada N et al. |
Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1380801
|
Friccius H et al. |
The effects of the antifungal azoles itraconazole, fluconazole, ketoconazole and miconazole on cytokine gene expression in human lymphoid cells. |
1992 |
Int. J. Immunopharmacol. |
pmid:1380951
|
Dumont FJ et al. |
The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin. |
1992 |
J. Exp. Med. |
pmid:1380976
|
Norris AA et al. |
Protective effects of cyclophosphamide, cyclosporin A and FK506 against antigen-induced lung eosinophilia in guinea-pigs. |
1992 |
Clin. Exp. Immunol. |
pmid:1381297
|
Griffin AD et al. |
FK 506 in canine renal transplantation. |
1992 |
Transplant. Proc. |
pmid:1384209
|
Griffiths RJ et al. |
Characterisation of passively transferred antigen arthritis induced by methylated bovine serum albumin in the rat: effect of FK 506 on arthritis development. |
1992 |
Agents Actions |
pmid:1384284
|
Todo S et al. |
Intestinal transplantation in composite visceral grafts or alone. |
1992 |
Ann. Surg. |
pmid:1384443
|
Massol N et al. |
Rabbit FKBP59-heat shock protein binding immunophillin (HBI) is a calmodulin binding protein. |
1992 |
Biochem. Biophys. Res. Commun. |
pmid:1384470
|
Siekierka JJ and Sigal NH |
FK-506 and cyclosporin A: immunosuppressive mechanism of action and beyond. |
1992 |
Curr. Opin. Immunol. |
pmid:1384551
|
Hultsch T et al. |
The effect of the immunophilin ligands rapamycin and FK506 on proliferation of mast cells and other hematopoietic cell lines. |
1992 |
Mol. Biol. Cell |
pmid:1384815
|
Petros AM et al. |
Identification of solvent-exposed regions of an FK-506 analog, ascomycin, bound to FKBP using a paramagnetic probe. |
1992 |
J. Biomol. NMR |
pmid:1384850
|
Liu J et al. |
The effects of FK-506 and cyclosporin A on the proliferation of PHA-stimulated T cells in response to IL-2, IL-4 or IL-6. |
1992 |
Int. Arch. Allergy Immunol. |
pmid:1384862
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
Doi R et al. |
Biochemical characterization of the effects of FK506 on signal transduction in exocytotic function of rat pancreatic acini. |
1993 |
J. Pharmacol. Exp. Ther. |
pmid:7679738
|
Cavaillé-Coll M and Mielach FA |
Choice of cyclophosphamide dose in baboon-to-human liver transplantation. |
1993 |
Lancet |
pmid:7679768
|
Zeevi A et al. |
Comparative in vitro studies on the immunosuppressive effects of purine and pyrimidine synthesis inhibitors. |
1993 |
Transplant. Proc. |
pmid:7679843
|
Inoue T et al. |
Isolation of mitochondrial cyclophilin from bovine heart. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7679902
|
Stephens J et al. |
Effects of orthotopic liver transplantation and immunosuppression on inflammatory bowel disease in primary sclerosing cholangitis patients. |
1993 |
Transplant. Proc. |
pmid:7680144
|
Bonet H et al. |
Survival of patients transplanted with alcoholic hepatitis plus cirrhosis as compared with those with cirrhosis alone. |
1993 |
Transplant. Proc. |
pmid:7680145
|
Jindal RM et al. |
Effect of deoxyspergualin on the endocrine function of the rat pancreas. |
1993 |
Transplantation |
pmid:7504347
|
Kodama M et al. |
FK506 therapy of experimental autoimmune myocarditis after onset of the disease. |
1993 |
Am. Heart J. |
pmid:7504393
|
Yem AW et al. |
An active FK506-binding domain of 17,000 daltons is isolated following limited proteolysis of chicken thymus hsp56. |
1993 |
Biochemistry |
pmid:7504525
|
Manev H et al. |
Macrolide antibiotics protect neurons in culture against the N-methyl-D-aspartate (NMDA) receptor-mediated toxicity of glutamate. |
1993 |
Brain Res. |
pmid:7504570
|
Doi R et al. |
Structural and functional changes of exocrine pancreas induced by FK506 in rats. |
1993 |
Gastroenterology |
pmid:7681795
|
Rotonda J et al. |
Improved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis. |
1993 |
J. Biol. Chem. |
pmid:7681823
|
Xu RX et al. |
1H, 13C, and 15N assignments and secondary structure of the FK506 binding protein when bound to ascomycin. |
1993 |
Biopolymers |
pmid:7682113
|
Tanaka N et al. |
Regulation of liver regeneration by interleukin-2 and its inhibitors: cyclosporine A and FK 506. |
1993 |
Int. J. Immunopharmacol. |
pmid:7682200
|
Quesniaux VF |
Immunosuppressants: tools to investigate the physiological role of cytokines. |
1993 |
Bioessays |
pmid:7507316
|
Storb R et al. |
FK-506 and methotrexate prevent graft-versus-host disease in dogs given 9.2 Gy total body irradiation and marrow grafts from unrelated dog leukocyte antigen-nonidentical donors. |
1993 |
Transplantation |
pmid:7692635
|
McDiarmid SV et al. |
A comparison of renal function in cyclosporine- and FK-506-treated patients after primary orthotopic liver transplantation. |
1993 |
Transplantation |
pmid:7692636
|
Tabasco-Minguillan J et al. |
Insulin requirements after liver transplantation and FK-506 immunosuppression. |
1993 |
Transplantation |
pmid:7692637
|
Takahara S |
Efficacy of FK506 in renal transplantation. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509132
|
Thomson AW et al. |
Incidence of CD4+ IL-2R alpha+ and CD4+ CD45RA+ T-cells in progressive multiple sclerosis and the influence of short-term (3 months) FK 506 therapy. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509133
|
Lemster B et al. |
FK 506 inhibits cytokine gene and adhesion molecule expression in psoriatic skin lesions. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509134
|
Tamura K et al. |
Inhibitory effect of FK 506 on autoimmune thyroid disease in the PVG rat. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509135
|
Ohtake M et al. |
Enhanced liver regeneration in rats treated with 15-deoxyspergualin alone and in combination with FK 506. |
1993 |
Gastroenterol. Jpn. |
pmid:7683616
|
Ohnishi H et al. |
Natural killer cell may impair liver regeneration in fulminant hepatic failure. |
1993 |
Gastroenterol. Jpn. |
pmid:7683619
|
Natazuka T et al. |
FK506 and cyclosporin a regulate proliferation and proto-oncogene expression in HTLV-1-associated myelopathy/tropical-spastic-paraparesis-derived T cells. |
1993 |
Int. J. Cancer |
pmid:7683633
|
Mukai H et al. |
FKBP12-FK506 complex inhibits phosphatase activity of two mammalian isoforms of calcineurin irrespective of their substrates or activation mechanisms. |
1993 |
J. Biochem. |
pmid:7683641
|
Wong PY et al. |
Recurrence of primary biliary cirrhosis after liver transplantation following FK506-based immunosuppression. |
1993 |
J. Hepatol. |
pmid:7686192
|
Sakr MF et al. |
FK 506 pre-treatment is associated with reduced levels of tumor necrosis factor and interleukin 6 following hepatic ischemia/reperfusion. |
1993 |
J. Hepatol. |
pmid:7686193
|
Calne RY et al. |
Intestinal transplant for recurring mesenteric desmoid tumour. |
1993 |
Lancet |
pmid:7686241
|
Hoof T et al. |
Reversal of multidrug resistance in Chinese hamster ovary cells by the immunosuppressive agent rapamycin. |
1993 |
Eur. J. Pharmacol. |
pmid:7689059
|
Jin YJ and Burakoff SJ |
The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7689229
|
Taylor-Fishwick DA et al. |
Evidence that rapamycin has differential effects of IL-4 function. Multiple IL-4 signaling pathways and implications for in vivo use. |
1993 |
Transplantation |
pmid:7689258
|
Shaefer MS et al. |
Falsely elevated FK-506 levels caused by sampling through central venous catheters. |
1993 |
Transplantation |
pmid:7689264
|
Jain AB et al. |
Pharmacokinetics of FK506 in liver transplant recipients after continuous intravenous infusion. |
1993 |
J Clin Pharmacol |
pmid:7690047
|
Cheng JW et al. |
15N NMR relaxation studies of the FK506 binding protein: backbone dynamics of the uncomplexed receptor. |
1993 |
Biochemistry |
pmid:7690248
|
Cetinkale O et al. |
The use of FK506 and skin allografting for the treatment of severe burns in an animal model. |
1993 |
Br J Plast Surg |
pmid:7690295
|
Talento A et al. |
A single administration of LFA-1 antibody confers prolonged allograft survival. |
1993 |
Transplantation |
pmid:7679531
|