tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adrenal Insufficiency D000309 3 associated lipids
Akinetic Mutism D000405 1 associated lipids
Albuminuria D000419 18 associated lipids
Alopecia D000505 14 associated lipids
Alopecia Areata D000506 6 associated lipids
Alzheimer Disease D000544 76 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Varshosaz J et al. Physicochemical, Pharmacodynamic and Pharmacokinetic Characterization of Soluplus Stabilized Nanosuspension of Tacrolimus. 2017 Curr Drug Deliv pmid:27697037
Cheung AY et al. Probable Donor-Derived Cytomegalovirus Disease After Keratolimbal Allograft Transplantation. 2017 Cornea pmid:28614157
Jouve T et al. New formulations of tacrolimus and prevention of acute and chronic rejections in adult kidney-transplant recipients. 2017 Expert Opin Drug Saf pmid:28494654
Koo K et al. Beyond monotherapy: a systematic review on creative strategies in topical therapy of psoriasis. 2017 J Dermatolog Treat pmid:28481664
Wolfshohl JA et al. Improvement of erythema dyschromicum perstans using a combination of the 1,550-nm erbium-doped fractionated laser and topical tacrolimus ointment. 2017 Lasers Surg Med pmid:27552666
Gardenier JC et al. Topical tacrolimus for the treatment of secondary lymphedema. 2017 Nat Commun pmid:28186091
Kizilbash SJ et al. Infection rates in tacrolimus versus cyclosporine-treated pediatric kidney transplant recipients on a rapid discontinuation of prednisone protocol: 1-year analysis. 2017 Pediatr Transplant pmid:28371243
Gard L et al. A delicate balance between rejection and BK polyomavirus associated nephropathy; A retrospective cohort study in renal transplant recipients. 2017 PLoS ONE pmid:28609473
Wang J et al. Comparative proteomic and metabolomic analysis of Streptomyces tsukubaensis reveals the metabolic mechanism of FK506 overproduction by feeding soybean oil. 2017 Appl. Microbiol. Biotechnol. pmid:28175948
Toyota H et al. Process optimization by use of design of experiments: Application for liposomalization of FK506. 2017 Eur J Pharm Sci pmid:28279762
Hamada T et al. Phenotypic analysis of circulating T-cell subset and its association with burden of skin disease in patients with chronic actinic dermatitis: a hematologic and clinicopathologic study of 20 subjects. 2017 Int. J. Dermatol. pmid:28176301
Schifferer M et al. Reversible Chemical Dimerization by rCD1. 2017 Meth. Enzymol. pmid:28063490
Percy C et al. Impact of Acute Infection Requiring Hospitalization on Tacrolimus Blood Levels in Kidney Transplant Recipients. 2017 Transplant. Proc. pmid:29149962
Obaidat RM et al. Using Supercritical Fluid Technology (SFT) in Preparation of Tacrolimus Solid Dispersions. 2017 AAPS PharmSciTech pmid:27116202
Taber DJ et al. A Comparative Effectiveness Analysis of Early Steroid Withdrawal in Black Kidney Transplant Recipients. 2017 Clin J Am Soc Nephrol pmid:27979979
Tron C et al. Tacrolimus: Does direct glucuronidation matter? An analytical and pharmacological perspective. 2017 Pharmacol. Res. pmid:28366836
Ganschow R et al. Everolimus and reduced calcineurin inhibitor therapy in pediatric liver transplant recipients: Results from a multicenter, prospective study. 2017 Pediatr Transplant pmid:28714558
Bremer S et al. NFAT-regulated cytokine gene expression during tacrolimus therapy early after renal transplantation. 2017 Br J Clin Pharmacol pmid:28686294
Tao X et al. Long-term efficacy and side effects of low-dose tacrolimus for the treatment of Myasthenia Gravis. 2017 Neurol. Sci. pmid:27873026
Tsunashima D et al. Development of extended-release solid dispersion granules of tacrolimus: evaluation of release mechanism and human oral bioavailability. 2017 J. Pharm. Pharmacol. pmid:28872687