Koch K et al. |
CP-123,369: a potent, orally active immunosuppressive agent. |
1995 |
Inflamm. Res. |
pmid:8548388
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Lionetti P et al. |
Mucosal adaptation and destruction in response to lamina propria T cell activation in explants of human fetal intestine. |
1995 |
Adv. Exp. Med. Biol. |
pmid:8525974
|
Ku YM et al. |
Compatibility of tacrolimus injection with cimetidine hydrochloride injection in 0.9% sodium chloride injection. |
1995 |
Am J Health Syst Pharm |
pmid:8528874
|
Arreaza G et al. |
Expression of intercellular adhesion molecule-1 on human thyroid cells from patients with autoimmune thyroid disease: study of thyroid xenografts in nude and severe combined immunodeficient mice and treatment with FK-506. |
1995 |
J. Clin. Endocrinol. Metab. |
pmid:8530625
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Braun W et al. |
Three-dimensional structure and actions of immunosuppressants and their immunophilins. |
1995 |
FASEB J. |
pmid:7529736
|
Zarnt T et al. |
Time-dependent inhibition of peptidylprolyl cis-trans-isomerases by FK506 is probably due to cis-trans isomerization of the inhibitor's imide bond. |
1995 |
Biochem. J. |
pmid:7529995
|
Wang CR et al. |
T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection. |
1995 |
J. Exp. Med. |
pmid:7532685
|
Wera S et al. |
Rapamycin, FK506 and cyclosporin A inhibit human prolactin gene expression. |
1995 |
FEBS Lett. |
pmid:7530217
|
Cao W et al. |
Effects of rapamycin on growth factor-stimulated vascular smooth muscle cell DNA synthesis. Inhibition of basic fibroblast growth factor and platelet-derived growth factor action and antagonism of rapamycin by FK506. |
1995 |
Transplantation |
pmid:7532879
|
Van Thiel DH et al. |
Tacrolimus (FK 506), a treatment for primary sclerosing cholangitis: results of an open-label preliminary trial. |
1995 |
Am. J. Gastroenterol. |
pmid:7532912
|
Ning YM and Sanchez ER |
Stabilization in vitro of the untransformed glucocorticoid receptor complex of S49 lymphocytes by the immunophilin ligand FK506. |
1995 |
J. Steroid Biochem. Mol. Biol. |
pmid:7532989
|
Teraoka S et al. |
Effect of rescue therapy using FK 506 on relapsing rejection after combined pancreas and kidney transplantation. |
1995 |
Transplant. Proc. |
pmid:7533381
|
Fay JW et al. |
FK 506-based immunosuppression for prevention of graft versus host disease after unrelated donor marrow transplantation. |
1995 |
Transplant. Proc. |
pmid:7533383
|
Murase N et al. |
Bone marrow augmentation for heart, liver, and small bowel transplantation: prolongation of graft survival and incidence of graft-versus-host disease. |
1995 |
Transplant. Proc. |
pmid:7533386
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Zeevi A et al. |
Serial evaluation of immune profiles of simultaneous bone marrow and whole organ transplant recipients. |
1995 |
Transplant. Proc. |
pmid:7533388
|
Watanabe K et al. |
Factors influencing long-term operational tolerance in dogs treated with fractionated lymphoid irradiation, donor bone marrow cell infusion and FK506. |
1995 |
Transplant. Proc. |
pmid:7533389
|
Wennberg L et al. |
Efficacy of various immunosuppressive drugs in preventing pig-to-rat islet xenograft rejection. |
1995 |
Transplant. Proc. |
pmid:7533391
|
Scantlebury VP et al. |
Renal transplantation under cyclosporine and FK 506 for hemolytic uremic syndrome. |
1995 |
Transplant. Proc. |
pmid:7533436
|
Hanafusa T et al. |
Long-term impact of hepatitis virus infection on kidney transplant recipients and a pilot study of the effects of interferon alpha on chronic hepatitis C. |
1995 |
Transplant. Proc. |
pmid:7533440
|
Bundick RV et al. |
The effect of cyclosporin A, FK506, and rapamycin on the murine chronic graft-versus-host response--an in vivo model of Th2-like activity. |
1995 |
Clin. Exp. Immunol. |
pmid:7533681
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Hirakata Y et al. |
Influence of various immunosuppressive agents on the occurrence of endogenous bacteraemia in mice. |
1995 |
J. Med. Microbiol. |
pmid:7533840
|
Gregory CR et al. |
Treatment with rapamycin and mycophenolic acid reduces arterial intimal thickening produced by mechanical injury and allows endothelial replacement. |
1995 |
Transplantation |
pmid:7533955
|
Tumlin JA et al. |
Expression of calcineurin activity and alpha-subunit isoforms in specific segments of the rat nephron. |
1995 |
Am. J. Physiol. |
pmid:7485542
|
Furukawa F et al. |
FK506: therapeutic effects on lupus dermatoses in autoimmune-prone MRL/Mp-lpr/lpr mice. |
1995 |
Arch. Dermatol. Res. |
pmid:7487142
|
Lapa e Silva JR et al. |
Modulation of the bronchial inflammation in sensitized guinea-pigs by FK506, nedocromil sodium and dexamethasone. |
1995 |
Eur. Respir. J. |
pmid:7489798
|
Shackleton CR et al. |
Lack of correlation between the magnitude of preservation injury and the incidence of acute rejection, need for OKT3, and conversion to FK506 in cyclosporine-treated primary liver allograft recipients. |
1995 |
Transplantation |
pmid:7570950
|
Min Z and Jones NF |
Limb transplantation in rats: immunosuppression with FK-506. |
1995 |
J Hand Surg Am |
pmid:7536766
|
Petrides AS |
[Do immunosuppressive agents really impair glucose tolerance in liver transplant patients?]. |
1995 |
Z Gastroenterol |
pmid:7571761
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Lyons WE et al. |
Neuronal regeneration enhances the expression of the immunophilin FKBP-12. |
1995 |
J. Neurosci. |
pmid:7536825
|
Thomson AW and Bonham CA |
Inhibition of T lymphocyte activation and apoptotic cell death by cyclosporin A and tacrolimus (FK506). Its relevance to therapy of HIV infection. |
1995 |
Adv. Exp. Med. Biol. |
pmid:7572394
|
Wortis HH et al. |
B-cell activation by crosslinking of surface IgM or ligation of CD40 involves alternative signal pathways and results in different B-cell phenotypes. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7536930
|
Bang H et al. |
Activation of Ca2+ signaling in neutrophils by the mast cell-released immunophilin FKBP12. |
1995 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7536932
|
Masaki Y et al. |
Cellular basis of acquired immunologic tolerance following total bowel transplantation in rats. I. Relation between donor lymphocyte chimerism and host-cell-mediated immunity. |
1995 |
Transplant. Proc. |
pmid:7536971
|
Garrett-Engele P et al. |
Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase. |
1995 |
Mol. Cell. Biol. |
pmid:7542741
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Baughman G et al. |
FKBP51, a novel T-cell-specific immunophilin capable of calcineurin inhibition. |
1995 |
Mol. Cell. Biol. |
pmid:7542743
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Warty V et al. |
Tacrolimus analysis: a comparison of different methods and matrices. |
1995 |
Ther Drug Monit |
pmid:7542809
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Freeman DJ et al. |
Stability of FK 506 in whole blood samples. |
1995 |
Ther Drug Monit |
pmid:7542810
|
Strumph P et al. |
The effect of FK506 on glycemic response as assessed by the hyperglycemic clamp technique. |
1995 |
Transplantation |
pmid:7542815
|
Dumont FJ et al. |
Dominant mutations confer resistance to the immunosuppressant, rapamycin, in variants of a T cell lymphoma. |
1995 |
Cell. Immunol. |
pmid:7538911
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Theopold U et al. |
FKBP39, a Drosophila member of a family of proteins that bind the immunosuppressive drug FK506. |
1995 |
Gene |
pmid:7538962
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Zhao Y et al. |
Calcineurin activation protects T cells from glucocorticoid-induced apoptosis. |
1995 |
J. Immunol. |
pmid:7539018
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Bronsther O et al. |
Liver transplantation for HBV-related disease under immunosuppression with tacrolimus: an experience with 78 consecutive cases. |
1995 |
J Okla State Med Assoc |
pmid:7539077
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Hoshino H et al. |
Effects of FK506 on an experimental model of colitis in rats. |
1995 |
Aliment. Pharmacol. Ther. |
pmid:7544633
|
Firdaous I et al. |
HPLC-microparticle enzyme immunoassay specific for tacrolimus in whole blood of hepatic and renal transplant patients. |
1995 |
Clin. Chem. |
pmid:7544705
|
Ingels SC et al. |
Stability of FK506 (tacrolimus) in whole-blood specimens. |
1995 |
Clin. Chem. |
pmid:7544707
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Hikita N et al. |
Effects of topical FK506 on endotoxin-induced uveitis (EIU) in the Lewis rat. |
1995 |
Curr. Eye Res. |
pmid:7540967
|
Takizawa H et al. |
Activated immunocompetent cells in rat colitis mucosa induced by dextran sulfate sodium and not complete but partial suppression of colitis by FK506. |
1995 |
Digestion |
pmid:7544748
|
Cardenas ME et al. |
Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A. |
1995 |
EMBO J. |
pmid:7540976
|
Sher LS and Makowka L |
Immunosuppression: now we have choices. |
1995 |
Hepatology |
pmid:7544759
|
Madsen KL et al. |
FK506 increases permeability in rat intestine by inhibiting mitochondrial function. |
1995 |
Gastroenterology |
pmid:7540994
|
Yang WM et al. |
Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity. |
1995 |
J. Biol. Chem. |
pmid:7541038
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Kawamura A and Su MS |
Interaction of FKBP12-FK506 with calcineurin A at the B subunit-binding domain. |
1995 |
J. Biol. Chem. |
pmid:7541044
|
Rao PN et al. |
Reduction of FK-506 requirements by combination with polyethylene glycol superoxide dismutase in orthotopic rat liver transplantation. |
1995 |
J. Allergy Clin. Immunol. |
pmid:7541060
|
Lauerma AI |
Immunomodulation of contact dermatitis. |
1995 |
Curr. Probl. Dermatol. |
pmid:7587333
|
Wera S et al. |
Cyclosporin A, rapamycin and FK506 decrease prolactin release from rat pituitary cells in primary culture. |
1995 |
Endocr. Res. |
pmid:7588431
|
Cameron AM et al. |
Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux. |
1995 |
Cell |
pmid:8521476
|
Stoller G et al. |
A ribosome-associated peptidyl-prolyl cis/trans isomerase identified as the trigger factor. |
1995 |
EMBO J. |
pmid:7588623
|
Tamura K |
FK506: mechanism of immunosuppression and adverse-effects. |
1995 |
J Toxicol Sci |
pmid:8531246
|
Farcasanu IC et al. |
Protein phosphatase 2B of Saccharomyces cerevisiae is required for tolerance to manganese, in blocking the entry of ions into the cells. |
1995 |
Eur. J. Biochem. |
pmid:7588708
|
Mugiya S et al. |
Renal blood flow, fibrinolysis, and platelet aggregation following tacrolimus (FK 506) treatment in rats. |
1995 |
Thromb. Res. |
pmid:8533130
|
Stemmer PM et al. |
Factors responsible for the Ca(2+)-dependent inactivation of calcineurin in brain. |
1995 |
FEBS Lett. |
pmid:7589543
|
Kaplan A et al. |
The effects of cyclosporin A and FK506 on proliferation and IL-8 production of cultured human keratinocytes. |
1995 |
J. Dermatol. Sci. |
pmid:8534611
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Zhu X et al. |
Enhancing and suppressive effects of immunosuppressants cyclosporin A, FK506, and KM2210 on the colony formation of murine bone marrow cells. |
1995 |
Ann. Hematol. |
pmid:8534762
|
Ockenfels HM et al. |
Tyrosine phosphorylation in psoriatic T cells is modulated by drugs that induce or improve psoriasis. |
1995 |
Dermatology (Basel) |
pmid:8534940
|
Vilquin JT et al. |
FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer. |
1995 |
Hum. Gene Ther. |
pmid:8573612
|
DÃaz M et al. |
[Tacrolimus (FK 506): an immunosuppression alternative in solid organ transplantation. (Part 2)]. |
1995 Apr-Jun |
Rev Med Univ Navarra |
pmid:7569553
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Hisatomi K et al. |
Effect of dose of cyclosporine or FK506 and antithrombotic agents on cardiac allograft vascular disease in heterotopically transplanted hearts in rats. |
1995 Jan-Feb |
J. Heart Lung Transplant. |
pmid:7537098
|
DÃaz M et al. |
[Tacrolimus (FK 506): immunosuppressive alternative to solid organ transplant (Part 1)]. |
1995 Jan-Mar |
Rev Med Univ Navarra |
pmid:14735715
|
Kawahara K et al. |
Effects of deoxyspergualin on bronchial anastomosis healing in canine pulmonary allografts. |
1995 Jul-Aug |
J. Heart Lung Transplant. |
pmid:7578196
|
Motoyama K et al. |
Pretransplant intrathymic inoculation of donor antigen combined with FK506 treatment: prolongation of survival of cardiac, but not renal, allografts in rats. |
1995 Mar-Apr |
World J Surg |
pmid:7538717
|
Okudaira H et al. |
Enhanced production and gene expression of interleukin-5 in patients with bronchial asthma: possible management of atopic diseases by down-regulation of interleukin-5 gene transcription. |
1995 May-Jun |
Int. Arch. Allergy Immunol. |
pmid:7542077
|
Su Q et al. |
Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase. |
1995 May-Jun |
Ren. Physiol. Biochem. |
pmid:7542793
|
Hayashi S et al. |
Evidence that donor pretreatment with FK506 has a synergistic effect on graft prolongation in hamster-to-rat heart xenotransplantation. |
1995 May-Jun |
J. Heart Lung Transplant. |
pmid:7544621
|
Castillo Lugo JA |
Clinical and experimental immunosuppression. |
1995 May-Jun |
Bol Asoc Med P R |
pmid:8573248
|
Seifeldin R |
Drug interactions in transplantation. |
1995 Nov-Dec |
Clin Ther |
pmid:8750397
|
Schreiber SL and Crabtree GR |
Immunophilins, ligands, and the control of signal transduction. |
1995-1996 |
Harvey Lect. |
pmid:9127988
|
Jin MB et al. |
Protective effect of FK 506 on hepatic energy metabolism in warm ischemic canine livers induced by total hepatic vascular exclusion. |
1996 |
Transplant. Proc. |
pmid:8623243
|
Smit JA et al. |
Induction of primate TH2 lymphokines to suppress TH1 cells. |
1996 |
Transplant. Proc. |
pmid:8623334
|
Appignani BA et al. |
Neuroimaging findings in patients on immunosuppressive therapy: experience with tacrolimus toxicity. |
1996 |
AJR Am J Roentgenol |
pmid:8623651
|
Asfar S et al. |
Small bowel transplantation. A life-saving option for selected patients with intestinal failure. |
1996 |
Dig. Dis. Sci. |
pmid:8625758
|
Esquivel CO et al. |
Suggested guidelines for the use of tacrolimus in pediatric liver transplant patients. |
1996 |
Transplantation |
pmid:8607198
|
Peters KP et al. |
The automatic search for ligand binding sites in proteins of known three-dimensional structure using only geometric criteria. |
1996 |
J. Mol. Biol. |
pmid:8609611
|
Lu YF et al. |
FK506, a Ca2+/calmodulin-dependent phosphatase inhibitor, inhibits the induction of long-term potentiation in the rat hippocampus. |
1996 |
Neurosci. Lett. |
pmid:8907327
|
Ye Q et al. |
Persistence of donor cells and incidence of graft-versus-host disease after simultaneous small bowel and bone marrow transplantation. |
1996 |
Transplant. Proc. |
pmid:8907895
|
Becker G et al. |
Diltiazem minimizes tubular damage due to FK506-mediated nephrotoxicity following ischemia and reperfusion in rats. |
1996 |
Transpl. Immunol. |
pmid:8762016
|
Paus R et al. |
Hair growth control by immunosuppression. |
1996 |
Arch. Dermatol. Res. |
pmid:8818191
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Woodle ES et al. |
Tacrolimus therapy for refractory acute renal allograft rejection: a prospective multicenter trial. Tacrolimus Kidney Transplantation Rescue Study Group. |
1996 |
Transplant. Proc. |
pmid:8962225
|
Scott-Douglas N et al. |
Treatment of acute renal transplant rejection with FK 506 in patients on cyclosporine after failure of standard antirejection therapy. |
1996 |
Transplant. Proc. |
pmid:8962226
|
Kliem V et al. |
FK 506 in the treatment of steroid- and OKT3-resistant rejection in renal transplant recipients: reduced dosage and anti-infective prophylaxis. |
1996 |
Transplant. Proc. |
pmid:8962227
|
Michel G et al. |
Antioncogene P53 and mitogenic cytokine interleukin-8 aberrantly expressed in psoriatic skin are inversely regulated by the antipsoriatic drug tacrolimus (FK506). |
1996 |
Biochem. Pharmacol. |
pmid:8787547
|
Gonschior AK et al. |
Tacrolimus (FK506) metabolite patterns in blood from liver and kidney transplant patients. |
1996 |
Clin. Chem. |
pmid:8787699
|
Karashima T et al. |
FK506 and cyclosporin A inhibit growth factor-stimulated human keratinocyte proliferation by blocking cells in the G0/G1 phases of the cell cycle. |
1996 |
J. Dermatol. Sci. |
pmid:8884530
|
Monfar M and Blenis J |
Inhibition of p70/p85 S6 kinase activities in T cells by dexamethasone. |
1996 |
Mol. Endocrinol. |
pmid:8885245
|
Kawabe A et al. |
Anti-adhesion (anti-ICAM-1 and anti-LFA-1) therapy in a rat pancreas transplantation model. |
1996 |
Transplant. Proc. |
pmid:8658893
|
Hayakawa K et al. |
Maintenance of unresponsiveness by short-term pulse therapy with FK 506 in rat transplantation. |
1996 |
Transplant. Proc. |
pmid:8658904
|
Cox KL and Freese DK |
Tacrolimus (FK506): the pros and cons of its use as an immunosuppressant in pediatric liver transplantation. |
1996 |
Clin Invest Med |
pmid:8889279
|
Mach-Pascual S et al. |
Microangiopathic hemolytic anemia complicating FK506 (tacrolimus) therapy. |
1996 |
Am. J. Hematol. |
pmid:8701950
|
Hemenway CS and Heitman J |
Immunosuppressant target protein FKBP12 is required for P-glycoprotein function in yeast. |
1996 |
J. Biol. Chem. |
pmid:8702500
|
Eckert B et al. |
Calcium-mobilizing insulin secretagogues stimulate transcription that is directed by the cyclic adenosine 3',5'-monophosphate/calcium response element in a pancreatic islet beta-cell line. |
1996 |
Endocrinology |
pmid:8536617
|
Wesselborg S et al. |
Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp). |
1996 |
J. Biol. Chem. |
pmid:8576111
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