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Mol Med Today |
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Clin Transplant |
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Postgrad Med J |
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Transplantation |
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FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain. |
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Immunosuppressor binding to the immunophilin FKBP59 affects the local structural dynamics of a surface beta-strand: time-resolved fluorescence study. |
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Measurement of tacrolimus (FK506) and its metabolites: a review of assay development and application in therapeutic drug monitoring and pharmacokinetic studies. |
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Mean field analysis of FKBP12 complexes with FK506 and rapamycin: implications for a role of crystallographic water molecules in molecular recognition and specificity. |
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Proteins |
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Biosynthesis of the shikimate-derived starter unit of the immunosuppressant ascomycin: stereochemistry of the 1,4-conjugate elimination. |
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Transplantation |
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Interactions between tacrolimus and antimicrobial agents. |
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Clin. Infect. Dis. |
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Lancet |
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Biol. Blood Marrow Transplant. |
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The immunosuppressant drug FK506 ameliorates secondary mitochondrial dysfunction following transient focal cerebral ischemia in the rat. |
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Clin Transplant |
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Proc. Natl. Acad. Sci. U.S.A. |
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An internal FK506-binding domain is the catalytic core of the prolyl isomerase activity associated with the Bacillus subtilis trigger factor. |
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FK506 enhances IL-13 production by T cells activated through CD3/CD28. |
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Structural organization of a multifunctional polyketide synthase involved in the biosynthesis of the macrolide immunosuppressant FK506. |
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1997 |
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Transplantation |
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A specific method for the measurement of tacrolimus in human whole blood by liquid chromatography/tandem mass spectrometry. |
1997 |
Ther Drug Monit |
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A yeast genetic system for selecting small molecule inhibitors of protein-protein interactions in nanodroplets. |
1997 |
Proc. Natl. Acad. Sci. U.S.A. |
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Use of topical FK506 in a corneal graft rejection model in Lewis rats. |
1997 |
Invest. Ophthalmol. Vis. Sci. |
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Clinical chemistry and post-liver-transplant monitoring. |
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Proc. Natl. Acad. Sci. U.S.A. |
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Could a herpesvirus mimic tacrolimus-induced leukoencephalopathy? |
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Acta Virol. |
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1997 |
Clin Transplant |
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1997 |
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Early signs and risk factors for the increased incidence of Epstein-Barr virus-related posttransplant lymphoproliferative diseases in pediatric liver transplant recipients treated with tacrolimus. |
1997 |
Transplantation |
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Invasive fungal infections in liver transplant recipients receiving tacrolimus as the primary immunosuppressive agent. |
1997 |
Clin. Infect. Dis. |
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Reversal of accelerated renal allograft rejection with FK 506. |
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Clin Transplant |
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[Flexibility of the surgical model of intestinal transplantation in swine]. |
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Minerva Chir |
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Br. J. Pharmacol. |
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Pure red cell aplasia due to parvovirus B19 infection in solid organ transplantation. |
1997 |
Clin Transplant |
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Influences of immunosuppressive agents, FK506 and cyclosporin on systemic Candida albicans infection in mice. |
1997 |
Mycopathologia |
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Stability of tacrolimus in an extemporaneously compounded oral liquid. |
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Am J Health Syst Pharm |
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1997 |
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Immunosuppression in auxiliary partial liver transplantation with FK506 in rats. |
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Transplant. Proc. |
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Transplant. Proc. |
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Outcome of kidney transplantation in African-Americans using tacrolimus. |
1997 |
Transplant. Proc. |
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Solitary pancreas transplantation for nonuremic patients with labile insulin-dependent diabetes mellitus. |
1997 |
Transplantation |
pmid:9415558
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Cholic acid synthesis is reduced in pediatric liver recipients during graft dysfunction due to ischemic injury and allograft rejection. |
1997 |
Transplantation |
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Modulation of energy status and cytotoxicity induced by FK506 and cyclosporin A in a renal epithelial cell line. |
1997 |
Arch. Toxicol. |
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Alopecia as a consequence of tacrolimus therapy in renal transplantation? |
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Transplantation |
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Tacrolimus in renal transplantation. |
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Nephrol. Dial. Transplant. |
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1997 |
Transpl. Int. |
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FK-506 and cyclosporin A potentiate the IgE antibody production by contact sensitization with hapten in mice. |
1997 |
J. Pharmacol. Exp. Ther. |
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Nifedipine interaction with tacrolimus in liver transplant recipients. |
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Ann Pharmacother |
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A local lymph node assay to analyse immunosuppressive effects of topically applied drugs. |
1997 |
Eur. J. Pharmacol. |
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Mycophenolate mofetil added to immunosuppression after liver transplantation--first results. |
1997 |
Transpl. Int. |
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Pathophysiology and treatment of lipid perturbation after cardiac transplantation. |
1997 |
Curr. Opin. Cardiol. |
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Gruessner RW and Sharp HL |
Living-related intestinal transplantation: first report of a standardized surgical technique. |
1997 |
Transplantation |
pmid:9415566
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Monitoring new immunosuppressive agents. Are the methods adequate? |
1997 |
Drug Metabol Drug Interact |
pmid:9713574
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Shaw LM |
Mycophenolate mofetil: pharmacokinetic strategies for optimizing immunosuppression. |
1997 |
Drug Metabol Drug Interact |
pmid:9713576
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Ilan Y et al. |
Transient immunosuppression with FK506 permits long-term expression of therapeutic genes introduced into the liver using recombinant adenoviruses in the rat. |
1997 |
Hepatology |
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Vella JP and Sayegh MH |
Maintenance pharmacological immunosuppressive strategies in renal transplantation. |
1997 |
Postgrad Med J |
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Gruessner AC and Sutherland DE |
Pancreas transplants for United States (US) and non-US cases as reported to the International Pancreas Transplant Registry (IPTR) and to the United Network for Organ Sharing (UNOS). |
1997 |
Clin Transpl |
pmid:9919390
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Secretion and composition of bile after human liver transplantation: studies on the effects of cyclosporine and tacrolimus. |
1997 |
Transplantation |
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Advances in pancreas transplantation: the University of Wisconsin experience. |
1997 |
Clin Transpl |
pmid:9919400
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Ciprofloxacin does not block the antiproliferative effect of tacrolimus. |
1997 |
Transplantation |
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Clinical aspects of sensitization. |
1997 |
Clin Transpl |
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Molecular cloning of human FKBP51 and comparisons of immunophilin interactions with Hsp90 and progesterone receptor. |
1997 |
Mol. Cell. Biol. |
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Pirenne J et al. |
Donor-specific unmodified bone marrow transfusion does not facilitate intestinal engraftment after bowel transplantation in a porcine model. |
1997 |
Surgery |
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Rescue therapy with tacrolimus (FK 506) in renal transplant recipients--a Scandinavian multicenter analysis. |
1997 |
Transpl. Int. |
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Rescue therapy with tacrolimus in simultaneous pancreas/kidney transplantation. |
1997 |
Transpl. Int. |
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Inhibition by rapamycin of ornithine decarboxylase and epithelial cell proliferation in intestinal IEC-6 cells in culture. |
1997 |
Br. J. Pharmacol. |
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Metabolism of tacrolimus (FK 506) in rat liver microsomes. Effect of rifampin and dexamethasone. |
1997 |
Res. Commun. Mol. Pathol. Pharmacol. |
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1997 |
Transplant. Proc. |
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Comparison of cyclosporine A and FK506 with regard to complaints and psychosocial characteristics before and after liver transplantation. |
1997 |
Transplant. Proc. |
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Pichlmayr R et al. |
Three-year follow-up of the European Multicenter Tacrolimus (FK506) Liver Study. |
1997 |
Transplant. Proc. |
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Cyclosporin A and FK506 reduce interleukin-5 mRNA abundance by inhibiting gene transcription. |
1997 |
Am. J. Respir. Cell Mol. Biol. |
pmid:9271313
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[Immunology in clinical practice. VI. Current immunosuppressive drugs]. |
1997 |
Ned Tijdschr Geneeskd |
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Multicenter randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of renal allograft rejection: a report of the European Tacrolimus Multicenter Renal Study Group. |
1997 |
Transplantation |
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Guérette B et al. |
Prevention by anti-LFA-1 of acute myoblast death following transplantation. |
1997 |
J. Immunol. |
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