| MeSH term | MeSH ID | Detail |
|---|---|---|
| Scorpion Stings | D065008 | 1 associated lipids |
| Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
| Retrognathia | D063173 | 1 associated lipids |
| End Stage Liver Disease | D058625 | 1 associated lipids |
| Candidiasis, Invasive | D058365 | 2 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Thrombotic Microangiopathies | D057049 | 1 associated lipids |
| Central Serous Chorioretinopathy | D056833 | 1 associated lipids |
| Leukoencephalopathies | D056784 | 3 associated lipids |
| Netherton Syndrome | D056770 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bishop DK and Li W | Cyclosporin A and FK506 mediate differential effects on T cell activation in vivo. | 1992 | J. Immunol. | pmid:1371128 |
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| Takaya S et al. | The adverse impact on liver transplantation of using positive cytotoxic crossmatch donors. | 1992 | Transplantation | pmid:1371195 |
| Francavilla A et al. | Inhibition of liver, kidney, and intestine regeneration by rapamycin. | 1992 | Transplantation | pmid:1371198 |
| Matsukawa W et al. | Effects of a new immunosuppressive agent, FK506, in rats with active Heymann nephritis. | 1992 | J. Lab. Clin. Med. | pmid:1371298 |
| Sampson BA and Gotschlich EC | Neisseria meningitidis encodes an FK506-inhibitable rotamase. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1371354 |
| Andersson J et al. | Effects of FK506 and cyclosporin A on cytokine production studied in vitro at a single-cell level. | 1992 | Immunology | pmid:1371491 |
| Strasser S et al. | Effect of FK506 on insulin secretion in normal dogs. | 1992 | Metab. Clin. Exp. | pmid:1371575 |
| Liu J et al. | Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. | 1992 | Biochemistry | pmid:1373650 |
| Adachi A et al. | Immunosuppressive effect of FK506 on experimental allergic neuritis in Lewis rats: change of T cell subsets. | 1992 | Intern. Med. | pmid:1373661 |
| Fruman DA et al. | Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1373887 |
| Lake JR et al. | Maintenance immunosuppression after liver transplantation. | 1992 | Semin. Liver Dis. | pmid:1373916 |
| Taormina D et al. | Stability and sorption of FK 506 in 5% dextrose injection and 0.9% sodium chloride injection in glass, polyvinyl chloride, and polyolefin containers. | 1992 | Am J Hosp Pharm | pmid:1373936 |
| Ochiai T | [Advances in the fundamentals and therapeutic use of immunosuppressive agents]. | 1992 | Arerugi | pmid:1374229 |
| Hung DT and Schreiber SL | cDNA cloning of a human 25 kDa FK506 and rapamycin binding protein. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1374240 |
| Jayaraman T et al. | FK506 binding protein associated with the calcium release channel (ryanodine receptor). | 1992 | J. Biol. Chem. | pmid:1374404 |
| Yasunami Y et al. | Induction of donor-specific unresponsiveness in rat islet allografts by FK 506. | 1992 | Transplant. Proc. | pmid:1376510 |
| Kai N et al. | A study on the timing of immunologic priming in autoimmune insulitis in NOD mice. | 1992 | Transplant. Proc. | pmid:1376511 |
| Ricordi C et al. | Effect of FK 506 on human pancreatic islets following renal subcapsular transplantation in diabetic nude mice. | 1992 | Transplant. Proc. | pmid:1376512 |
| Hisanaga M et al. | Successful combination therapy with FK 506 and 15-deoxyspergualin in pancreatic islet xenografting. | 1992 | Transplant. Proc. | pmid:1376513 |
| Ogasa N et al. | Successful transplantation of newborn rat intestine as a free graft. | 1992 | Transplant. Proc. | pmid:1376514 |
| Graeb C et al. | Cytoimmunologic monitoring of small bowel allograft recipients. | 1992 | Transplant. Proc. | pmid:1376515 |
| Date K et al. | Effect of FK 506 on graft survival in rat small intestinal allografts. | 1992 | Transplant. Proc. | pmid:1376516 |
| Hatazawa C et al. | Effect of FK 506 on bowel transplantation in rats. | 1992 | Transplant. Proc. | pmid:1376517 |
| Barry JM | Immunosuppressive drugs in renal transplantation. A review of the regimens. | 1992 | Drugs | pmid:1281071 |
| Stiff DD et al. | Metabolism of FK 506 in differentially induced rat liver microsomes. | 1992 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:1281332 |
| Foor F et al. | Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeast. | 1992 | Nature | pmid:1281518 |
| Goldfeld AE et al. | Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1281550 |
| Morikawa K et al. | The distinct effects of FK506 on the activation, proliferation, and differentiation of human B lymphocytes. | 1992 | Transplantation | pmid:1281561 |
| Moutabarrik A et al. | FK506-induced kidney tubular cell injury. | 1992 | Transplantation | pmid:1281562 |
| Yagihashi A et al. | HLA matching effect in liver transplantation. | 1992 | Transplant. Proc. | pmid:1281569 |
| Kobayashi M et al. | Posttransplant donor-specific T-lymphocytotoxic antibody in liver transplant patients with a positive crossmatch. | 1992 | Transplant. Proc. | pmid:1281570 |
| Takai K et al. | Effects of FK506 on rat thymic epithelial cells; immunohistochemical study. | 1992 | Thymus | pmid:1378235 |
| Dutz JP et al. | Effects of cognate peptides on cytolytic and proliferative activities of cloned cytotoxic T lymphocytes. | 1992 | Int. Immunol. | pmid:1378297 |
| Kenmochi T et al. | [The effect of FK506 on segmental pancreas allograft in mongrel dogs]. | 1992 | Nihon Geka Gakkai Zasshi | pmid:1378526 |
| Mouzaki A et al. | Cyclosporin A and FK506 prevent the derepression of the IL-2 gene in mitogen-induced primary T lymphocytes. | 1992 | Cytokine | pmid:1378764 |
| Ramamoorthy S et al. | Selective impairment of taurine transport by cyclosporin A in a human placental cell line. | 1992 | Pediatr. Res. | pmid:1378960 |
| Armitage JM et al. | Clinical trial of FK 506 immunosuppression in adult cardiac transplantation. | 1992 | Ann. Thorac. Surg. | pmid:1379032 |
| Thomson AW | The spectrum of action of new immunosuppressive drugs. | 1992 | Clin. Exp. Immunol. | pmid:1379130 |
| Fischer G et al. | Mip protein of Legionella pneumophila exhibits peptidyl-prolyl-cis/trans isomerase (PPlase) activity. | 1992 | Mol. Microbiol. | pmid:1379319 |
| Nielsen JB et al. | Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1380159 |
| Calvo V et al. | Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1380162 |
| Price DJ et al. | Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. | 1992 | Science | pmid:1380182 |
| Granelli-Piperno A | SRC-related proto-oncogenes and transcription factors in primary human T cells: modulation by cyclosporin A and FK506. | 1992 | J. Autoimmun. | pmid:1380242 |
| Reem GH | Molecular mode of action of cyclosporin and FK506 in human thymocytes. | 1992 | J. Autoimmun. | pmid:1380243 |
| Bach JF | Immunointervention in autoimmune diseases from cellular selectivity to autoantigen specificity. | 1992 | J. Autoimmun. | pmid:1380245 |
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| Walpoth B et al. | Assessment of new immunosuppressive drugs in a rat cardiac allograft heterotopic model. | 1992 | Eur Surg Res | pmid:1380460 |
| Hendey B et al. | Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. | 1992 | Science | pmid:1384129 |
| Roberti I et al. | Evidence that the systematic analysis of bile cytology permits monitoring of hepatic allograft rejection. | 1992 | Transplantation | pmid:1384182 |
| Langrehr JM et al. | Evidence that indefinite survival of small bowel allografts achieved by a brief course of cyclosporine or FK506 is not due to systemic hyporesponsiveness. | 1992 | Transplantation | pmid:1384185 |
| McCarthy SA et al. | The effects of immunosuppressive drugs on the regulation of activation-induced apoptotic cell death in thymocytes. | 1992 | Transplantation | pmid:1384186 |
| Dhar DK et al. | The salutary effect of FK506 in ischemia-reperfusion injury of the canine liver. | 1992 | Transplantation | pmid:1384188 |
| Ericzon BG et al. | FK506-induced impairment of glucose metabolism in the primate--studies in pancreatic transplant recipients and in nontransplanted animals. | 1992 | Transplantation | pmid:1384189 |
| Meiser BM et al. | Continuous infusion of angiopeptin significantly reduces accelerated graft vessel disease induced by FK 506 in a rat heart allograft model. | 1992 | Transplant. Proc. | pmid:1384201 |
| Wakabayashi H et al. | Effect of FK 506 and cyclosporine A on hepatic energy status in the rat after warm ischemia, as monitored by 31P nuclear magnetic resonance spectroscopy in vivo. | 1992 | Transplant. Proc. | pmid:1384205 |
| Mizuno K et al. | Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. | 1992 Jan-Feb | Anticancer Res. | pmid:1373592 |
| Arai S et al. | The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. | 1992 Jul-Aug | J. Heart Lung Transplant. | pmid:1379829 |
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| Tong J et al. | Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. | 1992 Jul-Aug | Haematologica | pmid:1385279 |
| Nazer H et al. | FK 506 associated disorders in liver transplantation. | 1992 May-Jun | J. Gastroenterol. Hepatol. | pmid:1377038 |
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| Shapiro R et al. | Randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone after renal transplantation: preliminary report. | 1993 | Transplant. Proc. | pmid:7679836 |
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| Winkler ME et al. | Successful pregnancy in a patient after liver transplantation maintained on FK 506. | 1993 | Transplantation | pmid:7506460 |
| Yoshizawa K et al. | Establishment of Epstein-Barr virus-associated lymphoma cell line SUBL with t(2;3)(p11;q27) from a liver transplant patient. | 1993 | Cancer Genet. Cytogenet. | pmid:7506636 |
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| Reem GH et al. | FK-506 inhibits the IL-2-independent induction of the activation antigen CD 69. | 1993 | Ann. N. Y. Acad. Sci. | pmid:7689811 |
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