Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Elloudi S et al. | [Frontal fibrosing alopecia: A prospective study of 20Â cases]. | Ann Dermatol Venereol | pmid:28258757 | |
Bethke G et al. | Swiss Dent J | pmid:28639684 | ||
Henrique Pinto C et al. | Targeted preemptive therapy according to perceived risk of CMV infection after kidney transplantation. | Braz J Infect Dis | pmid:27643978 | |
Errichetti E et al. | Annular elastolytic giant cell granuloma treated with topical pimecrolimus. | Indian J Dermatol Venereol Leprol | pmid:25201861 | |
Sathyan S et al. | Prevention of recurrent episodes of rhabdomyolysis with tacrolimus in a transplant recipient with myopathy. | Am J Ther | pmid:23429166 | |
Ge J et al. | Impact of FOXP3 Polymorphisms on the Blood Level of Tacrolimus in Renal Transplant Recipients. | Transplant. Proc. | pmid:27569929 | |
Hirohata A et al. | Oral tacrolimus for the treatment of generalized morphea. | Eur J Dermatol | pmid:26679400 | |
Ortiz de Frutos FJ | [New horizons in the treatment of atopic dermatitis]. | Allergol Immunopathol (Madr) | pmid:11988144 | |
Gómez-Sánchez ME et al. | Intralymphatic Histiocytosis: A Report of 2 Cases. | Actas Dermosifiliogr | pmid:28256202 | |
López-Oliva MO et al. | Switch to belatacept in kidney graft recipients. | Nefrologia | pmid:28233569 | |
Cakici O et al. | Periorbital discoid lupus: a rare localization in a patient with systemic lupus erythematosus. | An Bras Dermatol | pmid:28300917 | |
pmid:9123237 | ||||
Park JS et al. | Combinatory treatment using tacrolimus and a STAT3 inhibitor regulate Treg cells and plasma cells. | Int J Immunopathol Pharmacol | pmid:29873267 | |
Tahir W et al. | Diffuse Alveolar haemorrhage: a fatal complication after alemtuzumab induction therapy in renal transplantation. | Transplant. Proc. | pmid:25645795 | |
Jiménez-Pérez M et al. | Everolimus plus mycophenolate mofetil as initial immunosuppression in liver transplantation. | Transplant. Proc. | pmid:25645779 | |
Polanco N et al. | Everolimus-based immunosuppression therapy for BK virus nephropathy. | Transplant. Proc. | pmid:25645770 | |
Nunokawa T et al. | Late-onset scleroderma renal crisis induced by tacrolimus and prednisolone: a case report. | Am J Ther | pmid:22836123 | |
Paul GM et al. | Qualitative analysis of the deposit of collagen in bladder suture of rats treated with tacrolimus combined with mycophenolate-mofetil. | Int Braz J Urol | pmid:24856494 | |
López-Vilella R et al. | Incidence of development of obesity after heart transplantation according to the calcineurin inhibitor. | Transplant. Proc. | pmid:25645789 | |
Tinoco R et al. | [A case of de novo inflammatory bowel disease after liver transplantation for cryptogenic cirrhosis]. | Gastroenterol Hepatol | pmid:26321322 | |
Hoverson K et al. | Dermestid Dermatitis in a 2-Year-Old Girl: Case Report and Review of the Literature. | Pediatr Dermatol | pmid:26250481 | |
pmid:28590598 | ||||
Al-Amri AM et al. | Tacrolimus Ointment for Treatment of Vernal Keratoconjunctivitis. | Middle East Afr J Ophthalmol | pmid:26957853 | |
Collier DS et al. | FK-506 in experimental renal allografts. | 1987 | Transplant. Proc. | pmid:2445063 |
First International Workshop on FK-506. A potential breakthrough in immunosuppression. Proceedings. | 1987 | Transplant. Proc. | pmid:2445066 | |
Tanaka H et al. | Physicochemical properties of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. | 1987 | Transplant. Proc. | pmid:2445067 |
Honbo T et al. | The oral dosage form of FK-506. | 1987 | Transplant. Proc. | pmid:2445068 |
Tamura K et al. | A highly sensitive method to assay FK-506 levels in plasma. | 1987 | Transplant. Proc. | pmid:2445069 |
Venkataramanan R et al. | Biopharmaceutical aspects of FK-506. | 1987 | Transplant. Proc. | pmid:2445070 |
Kino T et al. | Effect of FK-506 on human mixed lymphocyte reaction in vitro. | 1987 | Transplant. Proc. | pmid:2445071 |
Goto T et al. | Discovery of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. | 1987 | Transplant. Proc. | pmid:2445072 |
Zeevi A et al. | Immunosuppressive effect of FK-506 on in vitro lymphocyte alloactivation: synergism with cyclosporine A. | 1987 | Transplant. Proc. | pmid:2445073 |
Sanghvi A et al. | FK-506 enhances cyclosporine uptake by peripheral blood lymphocytes. | 1987 | Transplant. Proc. | pmid:2445074 |
Ochiai T et al. | Prolongation of canine renal allograft survival by treatment with FK-506. | 1987 | Transplant. Proc. | pmid:2445075 |
Todo S et al. | Canine kidney transplantation with FK-506 alone or in combination with cyclosporine and steroids. | 1987 | Transplant. Proc. | pmid:2445076 |
Collier DS et al. | Kidney transplantation in the dog receiving FK-506. | 1987 | Transplant. Proc. | pmid:2445077 |
Calne R et al. | Observations about FK-506 in primates. | 1987 | Transplant. Proc. | pmid:2445078 |
Todo S et al. | Orthotopic liver transplantation in dogs receiving FK-506. | 1987 | Transplant. Proc. | pmid:2445079 |
Lim SM et al. | Heterotopic heart transplantation in the rat receiving FK-506. | 1987 | Transplant. Proc. | pmid:2445080 |
Murase N et al. | Heterotopic heart transplantation in the rat receiving FK-506 alone or with cyclosporine. | 1987 | Transplant. Proc. | pmid:2445081 |
Makowka L et al. | The effect of FK-506 on hyperacute rejection in presensitized rats. | 1987 | Transplant. Proc. | pmid:2445082 |
Ochiai T et al. | Effects of FK-506 on xenotransplantation of the heart and skin in a mouse-rat combination. | 1987 | Transplant. Proc. | pmid:2445083 |
Nalesnik MA et al. | Toxicology of FK-506 in the Lewis rat. | 1987 | Transplant. Proc. | pmid:2445084 |
Ochiai T et al. | Histopathologic studies in renal transplant recipient dogs receiving treatment with FK-506. | 1987 | Transplant. Proc. | pmid:2445085 |
Thiru S et al. | Pathological studies in canine and baboon renal allograft recipients immunosuppressed with FK-506. | 1987 | Transplant. Proc. | pmid:2445086 |
Kino T et al. | FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. | 1987 | J. Antibiot. | pmid:2445721 |
Kino T et al. | FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. | 1987 | J. Antibiot. | pmid:2445722 |
Ochiai T et al. | Studies of the effects of FK506 on renal allografting in the beagle dog. | 1987 | Transplantation | pmid:2447688 |
Ochiai T et al. | Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat. | 1987 | Transplant. Proc. | pmid:2484094 |
Sawada S et al. | Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation. | 1987 | J. Immunol. | pmid:2442255 |