Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dutta S et al. | Liposomal tacrolimus and intestinal drug concentration. | 1998 | Transplant. Proc. | pmid:9745533 |
Gasser M et al. | Effect of selective immunosuppression with FK 506, anti-IL-2R, and anti-ICAM-1 MAb in rat small bowel transplantation. | 1998 | Transplant. Proc. | pmid:9745510 |
Gatti S et al. | Graft-versus-host reaction and graft rejection after liver, small bowel or small bowel allotransplantation in the pig. | 1998 | Transplant. Proc. | pmid:9745509 |
Walgenbach KJ et al. | Upregulation of basic fibroblast growth factor during chronic rejection of rat intestinal allografts and its downregulation by FK 506. | 1998 | Transplant. Proc. | pmid:9745501 |
Chen H et al. | Combined effect of rapamycin and FK 506 in prolongation of small bowel graft survival in the mouse. | 1998 | Transplant. Proc. | pmid:9745497 |
Alessiani M et al. | Effect of perioperative donor bone marrow infusion after small bowel transplantation in swine: preliminary results. | 1998 | Transplant. Proc. | pmid:9745496 |
Quijano Y et al. | Tolerance: a study in long-term surviving animals after small bowel transplantation. | 1998 | Transplant. Proc. | pmid:9745494 |
Brooksbank RL et al. | Treatment of normal skeletal muscle with FK506 or rapamycin results in halothane-induced muscle contracture. | 1998 | Anesthesiology | pmid:9743407 |
Walensky LD et al. | The 12 kD FK 506 binding protein FKBP12 is released in the male reproductive tract and stimulates sperm motility. | 1998 | Mol. Med. | pmid:9742506 |
Reitamo S et al. | Tacrolimus ointment does not affect collagen synthesis: results of a single-center randomized trial. | 1998 | J. Invest. Dermatol. | pmid:9740230 |