Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Okada M et al. | Successful treatment of chronic graft-versus-host disease with sulfasalazine in allogeneic bone marrow transplantation. | 1999 | Acta Haematol. | pmid:10529517 |
Morita H et al. | Immunosuppressive effect of leukotriene B(4) receptor antagonist in vitro. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10529362 |
Cannon RD et al. | Clinical efficacy of the Abbott Tacrolimus II assay for the IMx. | 1999 Oct-Dec | Ann. Clin. Lab. Sci. | pmid:10528829 |
Grimbert P et al. | Tacrolimus (FK506)-induced severe and late encephalopathy in a renal transplant recipient. | 1999 | Nephrol. Dial. Transplant. | pmid:10528682 |
Shadidy M et al. | Biochemical analysis of mouse FKBP60, a novel member of the FKPB family. | 1999 | Biochim. Biophys. Acta | pmid:10524204 |
Lee SF et al. | Cytokine receptor common beta chain as a potential activator of cytokine withdrawal-induced apoptosis. | 1999 | Mol. Cell. Biol. | pmid:10523628 |
Mao Z and Wiedmann M | Calcineurin enhances MEF2 DNA binding activity in calcium-dependent survival of cerebellar granule neurons. | 1999 | J. Biol. Chem. | pmid:10521511 |
Hübner GI et al. | Drug interaction between mycophenolate mofetil and tacrolimus detectable within therapeutic mycophenolic acid monitoring in renal transplant patients. | 1999 | Ther Drug Monit | pmid:10519451 |
Yoshimoto T and Siesjö BK | Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia. | 1999 | Brain Res. | pmid:10519051 |
Pacocha SE et al. | Regulation of antigen-induced human T-lymphocyte responses by calcineurin antagonists. | 1999 | J. Allergy Clin. Immunol. | pmid:10518828 |
Bekersky I et al. | Bioequivalence of 1 and 5 mg tacrolimus capsules using a replicate study design. | 1999 | J Clin Pharmacol | pmid:10516937 |
Przepiorka D et al. | Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease after HLA-mismatched marrow or blood stem cell transplantation. | 1999 | Bone Marrow Transplant. | pmid:10516680 |
Moore JM | NMR techniques for characterization of ligand binding: utility for lead generation and optimization in drug discovery. | 1999 | Biopolymers | pmid:10516573 |
Cardenas ME et al. | Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action. | 1999 | Clin. Microbiol. Rev. | pmid:10515904 |
Cunningham EB | An inositolphosphate-binding immunophilin, IPBP12. | 1999 | Blood | pmid:10515881 |
Fan L et al. | Improved artificial death switches based on caspases and FADD. | 1999 | Hum. Gene Ther. | pmid:10515447 |
Charney DA et al. | Plasma cell-rich acute renal allograft rejection. | 1999 | Transplantation | pmid:10515379 |
Rostaing L et al. | Differences in Type 1 and Type 2 intracytoplasmic cytokines, detected by flow cytometry, according to immunosuppression (cyclosporine A vs. tacrolimus) in stable renal allograft recipients. | 1999 | Clin Transplant | pmid:10515221 |
Robinson BV et al. | Optimal dosing of intravenous tacrolimus following pediatric heart transplantation. | 1999 | J. Heart Lung Transplant. | pmid:10512526 |
Dusting GJ et al. | Cyclosporin A and tacrolimus (FK506) suppress expression of inducible nitric oxide synthase in vitro by different mechanisms. | 1999 | Br. J. Pharmacol. | pmid:10510443 |