Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Segura S et al. | Eczema herpeticum during treatment of atopic dermatitis with 1% pimecrolimus cream. | 2005 | Acta Derm. Venereol. | pmid:16396803 |
Mercader P et al. | Treatment of protein contact dermatitis with topical tacrolimus. | 2005 | Acta Derm. Venereol. | pmid:16396818 |
Mandelin J et al. | Leg ulcers treated with topical tacrolimus in patients with rheumatoid arthritis. | 2010 | Acta Derm. Venereol. | pmid:21057750 |
Honda Y et al. | Disseminated Mycobacterium mantenii infection with multiple purulent cutaneous lesions. | 2015 | Acta Derm. Venereol. | pmid:25881714 |
Tzung TY et al. | Pimecrolimus and narrowband UVB as monotherapy or combination therapy in children and adolescents with atopic dermatitis. | 2006 | Acta Derm. Venereol. | pmid:16585987 |
Pitarch G et al. | Systemic absorption of topical tacrolimus in Pyoderma gangrenosum. | 2006 | Acta Derm. Venereol. | pmid:16585995 |
Cunha PR | Pimecrolimus cream 1% is effective in seborrhoeic dermatitis refractory to treatment with topical corticosteroids. | 2006 | Acta Derm. Venereol. | pmid:16585998 |
Cunha PR and Rossi AB | Pimecrolimus cream 1% is effective in a case of granulomatous rosacea. | 2006 | Acta Derm. Venereol. | pmid:16585999 |
De Rie MA et al. | Soluble interleukin-2 receptor (sIL-2R) is a marker of disease activity in psoriasis: a comparison of sIL-2R, sCD27, sCD4, sCD8 and sICAM-1. | 1996 | Acta Derm. Venereol. | pmid:8891007 |
Kim TW et al. | Proactive treatment of adult facial seborrhoeic dermatitis with 0.1% tacrolimus ointment: randomized, double-blind, vehicle-controlled, multi-centre trial. | 2013 | Acta Derm. Venereol. | pmid:23388687 |