Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ohye H et al. | Effects of immunosuppressant agents on growth hormone release and gene expression. | 1998 | Endocr. J. | pmid:9790238 |
Casavilla FA et al. | Clinical outcome of patients infected with hepatitis C virus infection on survival after primary liver transplantation under tacrolimus. | 1998 | Liver Transpl Surg | pmid:9791154 |
Toshima K et al. | Effect of FK506 on the activation state of hepatic macrophages in Propionibacterium acnes-treated rats. | 1998 | J. Gastroenterol. Hepatol. | pmid:9792034 |
Sengoku T et al. | [Effects of tacrolimus ointment on type I (immediate and late) and IV (delayed) cutaneous allergic reactions in mice]. | 1998 | Nippon Yakurigaku Zasshi | pmid:9793077 |
Hashimoto Y et al. | Effects of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats. | 1998 | Pharm. Res. | pmid:9794505 |
Kobayashi M et al. | Effects of FK506 on experimental membranous glomerulonephritis induced by cationized bovine serum albumin in rats. | 1998 | Nephrol. Dial. Transplant. | pmid:9794552 |
Schaefer A et al. | Stimulation of the Ca2+-mediated egr-1 and c-fos expression in murine erythroleukaemia cells by cyclosporin A. | 1998 | Biochem. J. | pmid:9794788 |
Whitcup SM et al. | Topical liposome-encapsulated FK506 for the treatment of endotoxin-induced uveitis. | 1998 | Ocul. Immunol. Inflamm. | pmid:9798194 |
Sankary HN et al. | FK506 treatment in combination with leflunomide in hamster-to-rat heart and liver xenograft transplantation. | 1998 | Transplantation | pmid:9798690 |
Garcia-Criado FJ et al. | Possible tacrolimus action mechanisms in its protector effects on ischemia-reperfusion injury. | 1998 | Transplantation | pmid:9798713 |