| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adrenal Insufficiency | D000309 | 3 associated lipids |
| Akinetic Mutism | D000405 | 1 associated lipids |
| Albuminuria | D000419 | 18 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amenorrhea | D000568 | 4 associated lipids |
| Amputation, Traumatic | D000673 | 2 associated lipids |
| Anemia | D000740 | 21 associated lipids |
| Anemia, Aplastic | D000741 | 6 associated lipids |
| Anemia, Hemolytic | D000743 | 4 associated lipids |
| Anemia, Hemolytic, Autoimmune | D000744 | 5 associated lipids |
| Anemia, Refractory | D000753 | 3 associated lipids |
| Anemia, Refractory, with Excess of Blasts | D000754 | 2 associated lipids |
| Aneurysm, Dissecting | D000784 | 2 associated lipids |
| Angiolymphoid Hyperplasia with Eosinophilia | D000796 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Konma J et al. | Efficacy and safety of combination therapy with prednisolone and oral tacrolimus for progressive interstitial pneumonia with systemic sclerosis: A retrospective study. | 2018 | Mod Rheumatol | pmid:29442534 |
| Hashemian MN et al. | Topical Tacrolimus as Adjuvant Therapy to Corticosteroids in Acute Endothelial Graft Rejection After Penetrating Keratoplasty: A Randomized Controlled Trial. | 2018 | Cornea | pmid:29215395 |
| Huh KH et al. | De novo low-dose sirolimus versus mycophenolate mofetil in combination with extended-release tacrolimus in kidney transplant recipients: a multicentre, open-label, randomized, controlled, non-inferiority trial. | 2017 | Nephrol. Dial. Transplant. | pmid:28810721 |
| Choi SW et al. | Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT. | 2017 | Blood | pmid:28784598 |
| Lloberas N et al. | The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation. | 2017 | Pharmacogenet. Genomics | pmid:28704257 |
| Wu H et al. | Novel self-assembled tacrolimus nanoparticles cross-linking thermosensitive hydrogels for local rheumatoid arthritis therapy. | 2017 | Colloids Surf B Biointerfaces | pmid:27736727 |
| Gooptu M and Koreth J | Better acute graft--host disease outcomes for allogeneic transplant recipients in the modern era: a tacrolimus effect? | 2017 | Haematologica | pmid:28458253 |
| Chiasson VL et al. | Regulatory T-Cell Augmentation or Interleukin-17 Inhibition Prevents Calcineurin Inhibitor-Induced Hypertension in Mice. | 2017 | Hypertension | pmid:28584011 |
| Shoda W et al. | Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake. | 2017 | Kidney Int. | pmid:28341239 |
| Cakir U et al. | Role of Everolimus on Cardiac Functions in Kidney Transplant Recipients. | 2017 | Transplant. Proc. | pmid:28340820 |
| Hettiarachchi PVKS et al. | Comparison of topical tacrolimus and clobetasol in the management of symptomatic oral lichen planus: A double-blinded, randomized clinical trial in Sri Lanka. | 2017 | J Investig Clin Dent | pmid:27633647 |
| Zhang X et al. | Influence of IL-18 and IL-10 Polymorphisms on Tacrolimus Elimination in Chinese Lung Transplant Patients. | 2017 | Dis. Markers | pmid:28246425 |
| D'Avola D et al. | Cardiovascular morbidity and mortality after liver transplantation: The protective role of mycophenolate mofetil. | 2017 | Liver Transpl. | pmid:28160394 |
| Andreu F et al. | A New CYP3A5*3 and CYP3A4*22 Cluster Influencing Tacrolimus Target Concentrations: A Population Approach. | 2017 | Clin Pharmacokinet | pmid:28050888 |
| Maneechote C et al. | Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury. | 2017 | J. Cell. Mol. Med. | pmid:28941171 |
| Shrestha BM | Two Decades of Tacrolimus in Renal Transplant: Basic Science and Clinical Evidences. | 2017 | Exp Clin Transplant | pmid:27938316 |
| Yu MY et al. | Short-term anti-proteinuric effect of tacrolimus is not related to preservation of the glomerular filtration rate in IgA nephropathy: A 5-year follow-up study. | 2017 | PLoS ONE | pmid:29155873 |
| Gonzalez-Andrades M et al. | Sterile Corneal Infiltrates Secondary to Psoriasis Exacerbations: Topical Tacrolimus as an Alternative Treatment Option. | 2017 | Eye Contact Lens | pmid:26222098 |
| Olmedo MartÃn RV et al. | Medium to long-term efficacy and safety of oral tacrolimus in moderate to severe steroid refractory ulcerative colitis. | 2017 | Rev Esp Enferm Dig | pmid:28617029 |
| Pietrosi G and Chinnici C | Report on Liver Cell Transplantation Using Human Fetal Liver Cells. | 2017 | Methods Mol. Biol. | pmid:27830561 |