Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Winter C et al. | MAP kinase phosphatase 1 is expressed and enhanced by FK506 in surviving mamillary, but not degenerating nigral neurons following axotomy. | 1998 | Brain Res. | pmid:9729383 |
Horning NR et al. | Tacrolimus therapy for persistent or recurrent acute rejection after lung transplantation. | 1998 | J. Heart Lung Transplant. | pmid:9730424 |
Reichart B et al. | European Multicenter Tacrolimus (FK506) Heart Pilot Study: one-year results--European Tacrolimus Multicenter Heart Study Group. | 1998 | J. Heart Lung Transplant. | pmid:9730426 |
Meiser BM et al. | Single-center randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of acute myocardial rejection. | 1998 | J. Heart Lung Transplant. | pmid:9730427 |
Kawahara K et al. | Tracheal transplantation for carinal reconstruction in dogs. | 1998 | J. Thorac. Cardiovasc. Surg. | pmid:9731780 |
Cogill JL et al. | Evaluation of the tacrolimus II microparticle enzyme immunoassay (MEIA II) in liver and renal transplant recipients. | 1998 | Clin. Chem. | pmid:9732981 |
Sussman MA et al. | Prevention of cardiac hypertrophy in mice by calcineurin inhibition. | 1998 | Science | pmid:9733519 |
Wiesner RH | A long-term comparison of tacrolimus (FK506) versus cyclosporine in liver transplantation: a report of the United States FK506 Study Group. | 1998 | Transplantation | pmid:9734494 |
Hodak SP et al. | QT prolongation and near fatal cardiac arrhythmia after intravenous tacrolimus administration: a case report. | 1998 | Transplantation | pmid:9734501 |
Allen C et al. | Polycaprolactone-b-poly(ethylene oxide) block copolymer micelles as a novel drug delivery vehicle for neurotrophic agents FK506 and L-685,818. | 1998 Sep-Oct | Bioconjug. Chem. | pmid:9736490 |