Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Böttiger Y et al. | Tacrolimus whole blood concentrations correlate closely to side-effects in renal transplant recipients. | 1999 | Br J Clin Pharmacol | pmid:10510159 |
Lee WP and Mathes DW | Hand transplantation: pertinent data and future outlook. | 1999 | J Hand Surg Am | pmid:10509267 |
Sche PP et al. | Display cloning: functional identification of natural product receptors using cDNA-phage display. | 1999 | Chem. Biol. | pmid:10508685 |
Chautan M et al. | Interdigital cell death can occur through a necrotic and caspase-independent pathway. | 1999 | Curr. Biol. | pmid:10508592 |
Tredger JM et al. | Performance of the IMx tacrolimus II assay and practical limits of detection. | 1999 | Clin. Chem. | pmid:10508145 |
Cao Z et al. | Comparison of tacrolimus concentrations measured by the IMx tacrolimus II vs the PRO-TRAC II FK506 ELISA assays. | 1999 | Clin. Chem. | pmid:10508139 |
Cacciarelli TV et al. | An analysis of pretransplantation variables associated with long-term allograft outcome in pediatric liver transplant recipients receiving primary tacrolimus (FK506) therapy. | 1999 | Transplantation | pmid:10507484 |
Letko E et al. | Tacrolimus (FK 506). | 1999 | Ann. Allergy Asthma Immunol. | pmid:10507260 |
Linder MW and Elin RJ | Implications of methodologic bias for therapeutic drug monitoring. | 1999 | Arch. Pathol. Lab. Med. | pmid:10506447 |
Yoshimura R et al. | The effect of immunosuppressive agents (FK-506, rapamycin) on renal P450 systems in rat models. | 1999 | J. Pharm. Pharmacol. | pmid:10504034 |
Abu-Elmagd K et al. | Hepatic and intestinal transplantation at the University of Pittsburgh. | 1998 | Clin Transpl | pmid:10503105 |
Nakai T et al. | Immunologic changes in heterotopic and orthotopic small bowel transplantation in rats. | 1999 | Transplant. Proc. | pmid:10500761 |
Toki K et al. | Histopathologic findings in routine biopsies of renal transplant allografts. | 1999 | Transplant. Proc. | pmid:10500759 |
Ribas Y et al. | Lack of accommodation after long-term survival of hamster xenografts in rats. | 1999 | Transplant. Proc. | pmid:10500752 |
EscartÃn A et al. | Orthotopic small bowel transplantation in pigs without steroids. | 1999 | Transplant. Proc. | pmid:10500720 |
Chávez R et al. | Hepatotrophic effect of cyclosporine and FK 506 is not mimicked by rapamycin. | 1999 | Transplant. Proc. | pmid:10500655 |
Bárcena R et al. | Immunosuppression in liver transplantation: a European survey. | 1999 | Transplant. Proc. | pmid:10500654 |
González-Pinto I et al. | Usefulness of the switch to tacrolimus in liver transplantation. | 1999 | Transplant. Proc. | pmid:10500653 |
González MG et al. | Comparison of post-liver transplantation electrocardiographic alterations between cyclosporine- and tacrolimus-treated patients. | 1999 | Transplant. Proc. | pmid:10500652 |
GarcÃa González M et al. | Reversal of QT interval electrocardiographic alterations in cirrhotic patients undergoing liver transplantation. | 1999 | Transplant. Proc. | pmid:10500620 |