tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Platz KP et al. | Management of acute steroid-resistant rejection after liver transplantation. | 1996 | World J Surg | pmid:8798364 |
| Sutherland DE et al. | Pancreas transplantation for treatment of diabetes mellitus. | 2001 | World J Surg | pmid:11344403 |
| Kato T et al. | Intestinal and multivisceral transplantation. | 2002 | World J Surg | pmid:11865353 |
| Motoyama K et al. | Pretransplant intrathymic inoculation of donor antigen combined with FK506 treatment: prolongation of survival of cardiac, but not renal, allografts in rats. | 1995 Mar-Apr | World J Surg | pmid:7538717 |
| Montenegro F et al. | Surgical treatment of tertiary hyperparathyroidism: the choice of procedure matters! | 2008 | World J Surg | pmid:18204944 |
| Zong YP et al. | Effects of CYP3A5 polymorphisms on tacrolimus pharmacokinetics in pediatric kidney transplantation: a systematic review and meta-analysis of observational studies. | 2017 | World J Pediatr | pmid:28540692 |
| Yang EM et al. | Tacrolimus for children with refractory nephrotic syndrome: a one-year prospective, multicenter, and open-label study of Tacrobell®, a generic formula. | 2016 | World J Pediatr | pmid:26684309 |
| Kallash M and Aviles D | Efficacy of tacrolimus in the treatment of children with focal segmental glomerulosclerosis. | 2014 | World J Pediatr | pmid:24801235 |
| Schwarz C et al. | Rescue therapy with tacrolimus and mycophenolate mofetil does not prevent deterioration of graft function in C4d-positive chronic allograft nephropathy. | 2006 | Wien. Klin. Wochenschr. | pmid:16865644 |
| Sperr WR et al. | [Effector cells in allergy: biological principles and new pharmacologic concepts]. | 1993 | Wien. Klin. Wochenschr. | pmid:7508662 |
| Haas M et al. | Hypothyroidism as a cause of tacrolimus intoxication and acute renal failure: a case report. | 2000 | Wien. Klin. Wochenschr. | pmid:11144010 |
| Bakardzhiev I et al. | Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem. | 2016 | Wien Med Wochenschr | pmid:26762262 |
| Durrant-Finn U et al. | [Pruritus and dryness of the skin in chronic kidney insufficiency and dialysis patients - a review]. | 2009 | Wien Med Wochenschr | pmid:19652938 |
| TruneÄka P | [Immunosuppression after liver transplant, now and in future]. | 2013 | Vnitr Lek | pmid:24007221 |
| Kass L et al. | Inhibition of the calcineurin-like protein phosphatase activity in Limulus ventral eye photoreceptor cells alters the characteristics of the spontaneous quantal bumps and the light-mediated inward currents, and enhances arrestin phosphorylation. | 1998 Nov-Dec | Vis. Neurosci. | pmid:9839968 |
| Carbajo-Lozoya J et al. | Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir. | 2014 | Virus Res. | pmid:24566223 |
| Carbajo-Lozoya J et al. | Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506. | 2012 | Virus Res. | pmid:22349148 |
| Juvvadi PR et al. | Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach. | 2017 | Virulence | pmid:27325145 |
| Stremlau M et al. | Cyclophilin A: an auxiliary but not necessary cofactor for TRIM5alpha restriction of HIV-1. | 2006 | Virology | pmid:16643975 |
| Zhao W et al. | Role of cellular FKBP52 protein in intracellular trafficking of recombinant adeno-associated virus 2 vectors. | 2006 | Virology | pmid:16828834 |