Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Song JL et al. | Minimizing tacrolimus decreases the risk of new-onset diabetes mellitus after liver transplantation. | 2016 | World J. Gastroenterol. | pmid:26877618 |
Filipec Kanizaj T and Mijic M | Inflammatory bowel disease in liver transplanted patients. | 2017 | World J. Gastroenterol. | pmid:28566881 |
Provenzani A et al. | Pharmacogenetic considerations for optimizing tacrolimus dosing in liver and kidney transplant patients. | 2013 | World J. Gastroenterol. | pmid:24409044 |
Liu F et al. | Tacrolimus dosage requirements in living donor liver transplant recipients with small-for-size grafts. | 2009 | World J. Gastroenterol. | pmid:19701975 |
Schott E et al. | Development of ulcerative colitis in a patient with multiple sclerosis following treatment with interferon beta 1a. | 2007 | World J. Gastroenterol. | pmid:17659718 |
Jia JJ et al. | ''Minimizing tacrolimus'' strategy and long-term survival after liver transplantation. | 2014 | World J. Gastroenterol. | pmid:25170223 |
Hao JC et al. | Effect of low-dose tacrolimus with mycophenolate mofetil on renal function following liver transplantation. | 2014 | World J. Gastroenterol. | pmid:25170222 |
Kawakami K et al. | Effects of oral tacrolimus as a rapid induction therapy in ulcerative colitis. | 2015 | World J. Gastroenterol. | pmid:25684955 |
Meier J and Sturm A | Current treatment of ulcerative colitis. | 2011 | World J. Gastroenterol. | pmid:21912469 |
Buchholz BM et al. | Role of colectomy in preventing recurrent primary sclerosing cholangitis in liver transplant recipients. | 2018 | World J. Gastroenterol. | pmid:30065563 |