tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Laeijendecker R et al. | A comparison of treatment of oral lichen planus with topical tacrolimus and triamcinolone acetonide ointment. | 2006 | Acta Derm. Venereol. | pmid:16710580 |
| Quist SR et al. | Effects of Topical Tacrolimus and Polyunsaturated Fatty Acids on In Vivo Release of Eicosanoids in Atopic Dermatitis During Dermal Microdialysis. | 2016 | Acta Derm. Venereol. | pmid:26911315 |
| de la Rosa Carrillo D and Christensen OB | Treatment of chronic discoid lupus erythematosus with topical tacrolimus. | 2004 | Acta Derm. Venereol. | pmid:15202845 |
| Hartmann A et al. | Treatment of generalised vitiligo with tacrolimus 0.1% ointment vs. UVB intense pulsed light phototherapy: a pilot study. | 2014 | Acta Derm. Venereol. | pmid:24473666 |
| Granlund H et al. | Treatment of lichenified atopic eczema with tacrolimus ointment. | 2001 Aug-Sep | Acta Derm. Venereol. | pmid:11720192 |
| Murota H et al. | Olopatadine hydrochloride decreases tissue interleukin-31 levels in an atopic dermatitis mouse model. | 2014 | Acta Derm. Venereol. | pmid:23817562 |
| Heinemann C et al. | Topical tacrolimus in severe chronic graft-versus-host disease. | 2005 | Acta Derm. Venereol. | pmid:16191870 |
| Kirsner RS et al. | Safety and efficacy of tacrolimus ointment versus pimecrolimus cream in the treatment of patients with atopic dermatitis previously treated with corticosteroids. | 2010 | Acta Derm. Venereol. | pmid:20107727 |
| Larsen CG and Thyssen JP | Pustular penile pyoderma gangrenosum successfully treated with topical tacrolimus ointment. | 2012 | Acta Derm. Venereol. | pmid:21681352 |
| Fukamachi S et al. | Therapeutic effectiveness of various treatments for eosinophilic pustular folliculitis. | 2009 | Acta Derm. Venereol. | pmid:19326000 |
| Jacobs F et al. | New approach in combined therapy of perifolliculitis capitis abscedens et suffodiens. | 2011 | Acta Derm. Venereol. | pmid:21681358 |
| Hartmann A et al. | Occlusive treatment enhances efficacy of tacrolimus 0.1% ointment in adult patients with vitiligo: results of a placebo-controlled 12-month prospective study. | 2008 | Acta Derm. Venereol. | pmid:18779885 |
| Remitz A et al. | Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children. | 2007 | Acta Derm. Venereol. | pmid:17225017 |
| Virgili A et al. | Vulvar lichen sclerosus: 11 women treated with tacrolimus 0.1% ointment. | 2007 | Acta Derm. Venereol. | pmid:17225019 |
| Chittock J et al. | Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. | 2015 | Acta Derm. Venereol. | pmid:25594610 |
| Masuda K et al. | Increased levels of serum interleukin-16 in adult type atopic dermatitis. | 2003 | Acta Derm. Venereol. | pmid:12926794 |
| Mrowietz U et al. | An experimental ointment formulation of pimecrolimus is effective in psoriasis without occlusion. | 2003 | Acta Derm. Venereol. | pmid:14609102 |
| Jedlicková H et al. | Granuloma faciale successfully treated with topical tacrolimus: a case report. | 2008 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:18454269 |
| Thaçi D and Salgo R | The topical calcineurin inhibitor pimecrolimus in atopic dermatitis: a safety update. | 2007 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:17992459 |
| Vukićević J et al. | Unilateral multiple lichen striatus treated with tacrolimus ointment: a case report. | 2009 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:19350187 |