tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Pharmacol. Exp. Ther. (1)
- Am. J. Physiol. Renal Physiol. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang C et al. | Combining metabolomics and network analysis to improve tacrolimus production in Streptomyces tsukubaensis using different exogenous feedings. | 2017 | J. Ind. Microbiol. Biotechnol. | pmid:28776273 |
| Lim SW et al. | Klotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress. | 2017 | Cell Death Dis | pmid:28771227 |
| Savaj S et al. | Irreversible Lesions of Tacrolimus-induced Posterior Reversible Leukoencephalopathy Syndrome. | 2017 | Iran J Kidney Dis | pmid:29190599 |
| Shahid S et al. | Chronic hepatitis in the transplant patient. | 2017 | Br J Hosp Med (Lond) | pmid:28692371 |
| Liao JH et al. | Gene Variations of Sixth Complement Component Affecting Tacrolimus Metabolism in Patients with Liver Transplantation for Hepatocellular Carcinoma. | 2017 | Chin. Med. J. | pmid:28685716 |
| Filipec Kanizaj T and Mijic M | Inflammatory bowel disease in liver transplanted patients. | 2017 | World J. Gastroenterol. | pmid:28566881 |
| Seo SR et al. | Disrupted Skin Barrier is Associated with Burning Sensation after Topical Tacrolimus Application in Atopic Dermatitis. | 2017 | Acta Derm. Venereol. | pmid:28512670 |
| Egeland EJ et al. | High Tacrolimus Clearance Is a Risk Factor for Acute Rejection in the Early Phase After Renal Transplantation. | 2017 | Transplantation | pmid:28452920 |
| Aktürk S et al. | Average Tacrolimus Trough Level in the First Month After Transplantation May Predict Acute Rejection. | 2017 | Transplant. Proc. | pmid:28340806 |
| Vanhove T et al. | Effect of ABCB1 diplotype on tacrolimus disposition in renal recipients depends on CYP3A5 and CYP3A4 genotype. | 2017 | Pharmacogenomics J. | pmid:27378609 |
| Takagi K et al. | Syndrome of Inappropriate Antidiuretic Hormone Secretion Following Liver Transplantation. | 2017 | Acta Med. Okayama | pmid:28238015 |
| Sahutoglu T et al. | Tac-MMF Versus CsA-MMF/CsA-AZA-Based Regimens in Development of De Novo Complement-Binding Anti-HLA Antibodies After Kidney Transplantation. | 2017 | Transplant. Proc. | pmid:28340811 |
| Rebora A | Tacrolimus and oral lichen planus: the question remains. | 2017 | J Eur Acad Dermatol Venereol | pmid:27324047 |
| Størset E et al. | The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation. | 2017 | Br J Clin Pharmacol | pmid:28146606 |
| Dai Y et al. | A case report of coup de sabre patient with hair transplantation. | 2017 | J Dermatolog Treat | pmid:28142293 |
| Hashemizadeh Z et al. | Observational Study of Associations between Voriconazole Therapeutic Drug Monitoring, Toxicity, and Outcome in Liver Transplant Patients. | 2017 | Antimicrob. Agents Chemother. | pmid:28923870 |
| Pensi D et al. | First UHPLC-MS/MS method coupled with automated online SPE for quantification both of tacrolimus and everolimus in peripheral blood mononuclear cells and its application on samples from co-treated pediatric patients. | 2017 | J Mass Spectrom | pmid:28098395 |
| Calvo PL et al. | Donor CYP3A5 genotype influences tacrolimus disposition on the first day after paediatric liver transplantation. | 2017 | Br J Clin Pharmacol | pmid:28044353 |
| Wang L et al. | Efficacy and safety of tacrolimus for myasthenia gravis: a systematic review and meta-analysis. | 2017 | J. Neurol. | pmid:28921038 |
| Andrews LM et al. | Pharmacokinetic considerations related to therapeutic drug monitoring of tacrolimus in kidney transplant patients. | 2017 | Expert Opin Drug Metab Toxicol | pmid:29084469 |