| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhu ZJ et al. | [Diagnosis and treatment of de novo malignancy after liver transplantation]. | 2007 | Zhonghua Zhong Liu Za Zhi | pmid:17649647 |
| Dong J et al. | [Osteoblastic differentiation and in vivo osteogenic activity of marrow-derived mesenchymal stem cells stimulated by Tacrolimus: experiment with rats]. | 2007 | Zhonghua Yi Xue Za Zhi | pmid:17425851 |
| Liang TB et al. | [Graft versus host disease after liver transplantation: a report of 3 cases]. | 2004 | Zhonghua Yi Xue Za Zhi | pmid:15200885 |
| Wang W et al. | [Relationship between MDR1 gene polymorphism and blood concentration of tacrolimus in renal transplant patients]. | 2005 | Zhonghua Yi Xue Za Zhi | pmid:16409819 |
| Chen YH et al. | [Nephrotoxicity of tacrolimus and preventive effect of diltiazem: experiment with rats]. | 2009 | Zhonghua Yi Xue Za Zhi | pmid:19595068 |
| Lu AW et al. | [Dual, triple, and quadruple oral tacrolimus-based immunosuppression regimens after orthotopic liver transplantation: a randomised comparative study of regimens]. | 2006 | Zhonghua Yi Xue Za Zhi | pmid:17313848 |
| Huang G et al. | [Analysis on BK virus associated nephropathy related risk factors in renal transplant recipients]. | 2015 | Zhonghua Yi Xue Za Zhi | pmid:26814103 |
| Pan F et al. | [Protective effect of tacrolimus postconditioning on oxidative stress injury provoked by spinal cord ischemia-reperfusion in rats]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24548402 |
| Dong QE et al. | [Inhibitory effects of tacrolimus on effector T cells from patients with severe aplastic anemia]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24028719 |
| Li YX et al. | [Preliminary experience with partial tolerance protocol in small bowel transplantation]. | 2009 | Zhonghua Yi Xue Za Zhi | pmid:20137270 |
| Feng HY et al. | [Therapeutic efficacy and safety of tacrolimus for intractable myasthenia gravis: a report of 36 patients]. | 2011 | Zhonghua Yi Xue Za Zhi | pmid:22333101 |
| Huang HF et al. | [Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: a 4-year prospective study]. | 2011 | Zhonghua Yi Xue Za Zhi | pmid:22333250 |
| Chen H et al. | [Mycophenolate mofetil in treatment of graft-versus-host disease after allogeneic hematopoietic cell transplantation: analysis of 44 cases]. | 2008 | Zhonghua Yi Xue Za Zhi | pmid:19080474 |
| Zhao SM et al. | [Promotion of in vitro long term expansion of primitive multipotential hematopoietic cells by transduced JAK2 gene]. | 2004 | Zhonghua Yi Xue Za Zhi | pmid:15329285 |
| Chen YH et al. | [Prevention of diltiazem in tacrolimus-induced nephrotoxicity: experiment with rats]. | 2007 | Zhonghua Yi Xue Za Zhi | pmid:18001539 |
| Li YL et al. | [Measurement of tacrolimus in blood with the method of high performance liquid chromatography-mass spectrometry]. | 2008 | Zhonghua Yi Xue Za Zhi | pmid:19087682 |
| Cai JQ et al. | [Study of the effects of immunosuppressive agents on human islet cells in vitro]. | 2005 | Zhonghua Yi Xue Za Zhi | pmid:15932724 |
| Wang J and Fan H | [Assessment of P70S6 kinase phosphorylation after liver transplantation by phospho-flow cytometry]. | 2014 | Zhonghua Yi Xue Za Zhi | pmid:25623311 |
| Xia WL et al. | [Effects of ciclosporin and tacrolimus on replication of hepatitis B virus in vitro: a comparative study]. | 2006 | Zhonghua Yi Xue Za Zhi | pmid:16620716 |
| Lü DC et al. | [Effect of FK506 on axonal regeneration of rat sciatic nerve in regeneration chamber: an experimental study]. | 2005 | Zhonghua Yi Xue Za Zhi | pmid:16313776 |
| Zhang WG et al. | [Favorable effect of chitosan sustained-release FK506 incorporated conduits on axonal regeneration in rat sciatic nerve]. | 2006 | Zhonghua Yi Xue Za Zhi | pmid:16784713 |
| Jin J et al. | Impact of multidrug resistance 1 gene polymorphism on tacrolimus dose and concentration-to-dose ratio in Chinese liver transplantation recipients. | 2005 | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | pmid:16331555 |
| Xie H et al. | [Effect of FK506 eye-drop combined with keratoplasty on recurrent Mooren's ulcer]. | 2002 | Zhonghua Yan Ke Za Zhi | pmid:11955293 |
| Chen J et al. | [The study of FK506 eye drops preventing and treating immune rejection on limbal allograft transplantation]. | 2003 | Zhonghua Yan Ke Za Zhi | pmid:14766087 |
| Xiang DM et al. | [The observation of tacrolimus eye drops preventing the early immunological rejection after penetrating keratoplasty for fungal keratitis]. | 2017 | Zhonghua Yan Ke Za Zhi | pmid:28412805 |
| Sun YJ et al. | [Systematic review of penetrating keratoplasty rejection treated by immunosuppressants]. | 2010 | Zhonghua Yan Ke Za Zhi | pmid:21211228 |
| Shi WY et al. | [Implantation of FK506 drug delivery system into the anterior chamber for inhibiting corneal rejection in high risk rabbit corneal allograft]. | 2006 | Zhonghua Yan Ke Za Zhi | pmid:16762204 |
| Fei WL et al. | [The pharmacokinetics of FK506 and its nanoparticles in aqueous humor of rabbits]. | 2006 | Zhonghua Yan Ke Za Zhi | pmid:16762205 |
| Lü L et al. | [Experimental studies on the effect of the immunosuppressant FK-506 on penetrating keratoplasty rejection model in rats]. | 1999 | Zhonghua Yan Ke Za Zhi | pmid:11835769 |
| Lü L and Zhang W | [Immunopathologic studies on the effects of immunosuppressant FK 506 on penetrating keratoplasty rejection model in rat]. | 1998 | Zhonghua Yan Ke Za Zhi | pmid:11877144 |
| DU C et al. | [In vitro effects of tacrolimus on platelet function]. | 2014 | Zhonghua Xue Ye Xue Za Zhi | pmid:25339327 |
| Zhao SM et al. | [Long term regulated expansion and committed differentiation of JAK2 gene transfected hematopoietic stem/progenitor cells in vitro]. | 2004 | Zhonghua Xue Ye Xue Za Zhi | pmid:14990041 |
| Chen F et al. | [Outcomes of allogeneic hematopoietic stem cell transplantation for 18 patients with paroxysmal nocturnal haemoglobinuria]. | 2015 | Zhonghua Xue Ye Xue Za Zhi | pmid:26759101 |
| Sun J et al. | [A preliminary study on the biological characteristics and function of tolerogenic dendritic cells induced by tacrolimus]. | 2014 | Zhonghua Xue Ye Xue Za Zhi | pmid:24985179 |
| Cao KJ et al. | [Immunosuppressive therapy after human lung transplantation]. | 2007 | Zhonghua Wai Ke Za Zhi | pmid:17845780 |
| Li YX et al. | [Preliminary experience with Campath 1H induction combined with low-dose monotherapy of tacrolimus in small bowel transplantation]. | 2009 | Zhonghua Wai Ke Za Zhi | pmid:19961008 |
| Pan F et al. | [Effect of tacrolimus on apoptosis and expression of heat shock protein 70 after acute spinal cord injury in rats]. | 2006 | Zhonghua Wai Ke Za Zhi | pmid:17359722 |
| Lü DC et al. | [An experimental study of the neuroprotective effect of FK506 on acute spinal cord injury in dogs]. | 2005 | Zhonghua Wai Ke Za Zhi | pmid:16194341 |
| Zhao X et al. | [A retrospective cohort study regarding the effect of sirolimus-based immunosuppression protocol on the long-term survival of hepatocellular carcinoma patients after liver transplantation]. | 2014 | Zhonghua Wai Ke Za Zhi | pmid:24924566 |
| Ju WQ et al. | [Two-dose steroid combined with two-dose daclizumab and tacrolimus regimen in liver transplant recipients]. | 2009 | Zhonghua Wai Ke Za Zhi | pmid:19781270 |
| Hu AB et al. | [Evaluation of efficacy and safety on steroid withdraw at the seventh day after liver transplantation]. | 2008 | Zhonghua Wai Ke Za Zhi | pmid:19094670 |
| Yang FC et al. | [Influence of combined cyclosporine A and tacrolimus with 5-fluorouracil on hepatocellular carcinoma rats]. | 2003 | Zhonghua Wai Ke Za Zhi | pmid:12895356 |
| Chen YP et al. | [The clinical efficacy and safety of tacrolimus in patients with myasthenia gravis]. | 2013 | Zhonghua Nei Ke Za Zhi | pmid:24266997 |
| Sun L et al. | [Effect of FK506 on the cavernous nerve regeneration after injury]. | 2005 | Zhonghua Nan Ke Xue | pmid:15755036 |
| Cao ZG et al. | [Effects of different immunodepressants on the sperm parameters of kidney transplant recipients]. | 2006 | Zhonghua Nan Ke Xue | pmid:16755867 |
| Zhao S et al. | [Effects of tacrolimus (FK506) on heat-shock proteins 70, Bcl-2 and Bax expression in nervous tissue of acrylamide-induced rat]. | 2010 | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | pmid:20465949 |
| Sun YJ and Sun Z | [Treatment of erosive oral lichen planus with topical tacrolimus]. | 2010 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:20450689 |
| Zhang J et al. | [Effects of sirolimus on the growth of transplanted hepatocellular carcinoma]. | 2009 | Zhonghua Gan Zang Bing Za Zhi | pmid:19567017 |
| Qian SK et al. | [The prevention and management of cerebrovascular complications in nine cases after orthotopic liver transplantation]. | 2005 | Zhonghua Gan Zang Bing Za Zhi | pmid:16313741 |
| Huang K et al. | [Prophylaxis and treatment of chronic graft versus host disease]. | 2005 | Zhonghua Er Ke Za Zhi | pmid:15833186 |