tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Hypercalcemia D006934 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Azuma N et al. Immunosuppression with FK506 in rat arterial allografts: fate of allogeneic endothelial cells. 1999 J. Vasc. Surg. pmid:10194498
Mollison KW et al. Discovery of ascomycin analogs with potent topical but weak systemic activity for treatment of inflammatory skin diseases. 1998 Curr. Pharm. Des. pmid:10197049
De Lima JJ et al. Effects of FK506 in rat and human resistance arteries. 1999 Kidney Int. pmid:10201018
Sloper CM et al. Tacrolimus (FK506) in the treatment of posterior uveitis refractory to cyclosporine. 1999 Ophthalmology pmid:10201592
Nagasaki Y et al. Reversal of hypopigmentation in phenylketonuria mice by adenovirus-mediated gene transfer. 1999 Pediatr. Res. pmid:10203136
Hortelano S et al. Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages. 1999 Br. J. Pharmacol. pmid:10205001
Cetinkale O et al. Modulating the functions of neutrophils and lipid peroxidation by FK506 in a rat model of thermal injury. 1999 Burns pmid:10208383
Lütkes P et al. [Quality of life following transplantation. The impact ofa new immunosuppressive substance]. 1999 Zentralbl Chir pmid:10209841
Jani A et al. Modulation of cell-mediated immunity prolongs adenovirus-mediated transgene expression in sciatic nerve. 1999 Hum. Gene Ther. pmid:10210146
Knoll GA and Bell RC Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trials. 1999 BMJ pmid:10213717