| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
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| Steinbach WJ et al. | In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus. | 2004 | Antimicrob. Agents Chemother. | pmid:15105118 |
| Sun S et al. | In vitro interactions between tacrolimus and azoles against Candida albicans determined by different methods. | 2008 | Antimicrob. Agents Chemother. | pmid:18056277 |
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| Pea F et al. | Drop in trough blood concentrations of tacrolimus after switching from nelfinavir to fosamprenavir in four HIV-infected liver transplant patients. | 2008 | Antivir. Ther. (Lond.) | pmid:18771060 |
| Ginestà MM et al. | Acute xenograft rejection, late xenograft rejection and long term survival xenografts in the hamster-to-rat heart transplantation model: histological characterisation under low-dose of FK506. | 2002 | APMIS | pmid:12583441 |
| Kuo WW et al. | Cardiomyoblast apoptosis induced by insulin-like growth factor (IGF)-I resistance is IGF-II dependent and synergistically enhanced by angiotensin II. | 2006 | Apoptosis | pmid:16699953 |
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| Ordóñez-Robles M et al. | Target genes of the Streptomyces tsukubaensis FkbN regulator include most of the tacrolimus biosynthesis genes, a phosphopantetheinyl transferase and other PKS genes. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27357227 |
| Salehi-Najafabadi Z et al. | Characterisation of a γ-butyrolactone receptor of Streptomyces tacrolimicus: effect on sporulation and tacrolimus biosynthesis. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21792593 |
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| Lübbe J et al. | Adults with atopic dermatitis and herpes simplex and topical therapy with tacrolimus: what kind of prevention? | 2003 | Arch Dermatol | pmid:12756112 |
| Allen A et al. | Significant absorption of topical tacrolimus in 3 patients with Netherton syndrome. | 2001 | Arch Dermatol | pmid:11405764 |
| Systemic tacrolimus (FK 506) is effective for the treatment of psoriasis in a double-blind, placebo-controlled study. The European FK 506 Multicentre Psoriasis Study Group. | 1996 | Arch Dermatol | pmid:8629845 | |
| Van Leent EJ et al. | Effectiveness of the ascomycin macrolactam SDZ ASM 981 in the topical treatment of atopic dermatitis. | 1998 | Arch Dermatol | pmid:9681343 |
| Passeron T et al. | Topical tacrolimus and the 308-nm excimer laser: a synergistic combination for the treatment of vitiligo. | 2004 | Arch Dermatol | pmid:15381545 |
| Bunker CB et al. | Topical tacrolimus, genital lichen sclerosus, and risk of squamous cell carcinoma. | 2004 | Arch Dermatol | pmid:15381566 |
| Ehst BD and Warshaw EM | Alcohol-induced application site erythema after topical immunomodulator use and its inhibition by aspirin. | 2004 | Arch Dermatol | pmid:15313828 |
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| Laino L and DiCarlo A | Palmoplantar pustular psoriasis: clinical and video thermographic evaluation before and after topical tacrolimus treatment. | 2011 | Arch Dermatol | pmid:21690553 |
| Eiling E et al. | Pimecrolimus: a novel treatment for cetuximab-induced papulopustular eruption. | 2008 | Arch Dermatol | pmid:18794482 |
| Byrd JA et al. | Response of oral lichen planus to topical tacrolimus in 37 patients. | 2004 | Arch Dermatol | pmid:15611431 |
| Santos-Juanes J et al. | Topical tacrolimus: an effective therapy for Zoon balanitis. | 2004 | Arch Dermatol | pmid:15611442 |
| Milingou M et al. | Alcohol intolerance and facial flushing in patients treated with topical tacrolimus. | 2004 | Arch Dermatol | pmid:15611445 |
| Yan AC et al. | The safety and efficacy of pimecrolimus, 1%, cream for the treatment of Netherton syndrome: results from an exploratory study. | 2010 | Arch Dermatol | pmid:20083693 |
| Ciurea AM et al. | Complete and durable clinical response of malignant pyoderma to tacrolimus in combination with dapsone and prednisone. | 2010 | Arch Dermatol | pmid:20083712 |
| Mikhail M et al. | Rapid enlargement of a malignant melanoma in a child with vitiligo vulgaris after application of topical tacrolimus. | 2008 | Arch Dermatol | pmid:18427063 |
| Kunstfeld R et al. | Successful treatment of vulvar lichen sclerosus with topical tacrolimus. | 2003 | Arch Dermatol | pmid:12873877 |
| Böhm M et al. | Successful treatment of anogenital lichen sclerosus with topical tacrolimus. | 2003 | Arch Dermatol | pmid:12873890 |
| Allen DM and Esterly NB | Significant systemic absorption of tacrolimus after topical application in a patient with lamellar ichthyosis. | 2002 | Arch Dermatol | pmid:12225004 |