| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gerber DA et al. | Immunosuppressive agents: recent developments in molecular action and clinical application. | 1998 | Transplant. Proc. | pmid:9636637 |
| Schneeberger H et al. | Tacrolimus as a primary immunosuppressive therapy in cadaveric renal transplantation: five years' experience at a single center. | 1998 | Transplant. Proc. | pmid:9636642 |
| Resch K and Szamel M | Molecular mechanisms of the immunosuppressive action of cyclosporin A. | 1997 Sep-Oct | Int. J. Immunopharmacol. | pmid:9637358 |
| Baldari CT et al. | NF-AT-luciferase reporter T cell lines as tools to screen immunosuppressive drugs. | 1998 | Biologicals | pmid:9637743 |
| Abraham RT | Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling. | 1998 | Curr. Opin. Immunol. | pmid:9638370 |
| Takahara S et al. | A comparative study of FK506 granules and capsules in renal transplant recipients. | 1998 | Transpl. Int. | pmid:9638846 |
| Morris-Stiff G and Jurewicz WA | Single centre experience with mycophenolate mofetil for refractory rejection in cadaveric renal transplantation. | 1998 | Transpl. Int. | pmid:9638849 |
| Murray M et al. | Comparison of tacrolimus absorption in transplant patients receiving continuous versus interrupted enteral nutritional feeding. | 1998 | Ann Pharmacother | pmid:9640479 |
| Kuwata T et al. | A role of calcineurin in coreceptor regulation during differentiation of Cd4+Cd8+ T cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9642110 |
| Gruessner RW et al. | Suggested guidelines for the use of tacrolimus in pancreas/kidney transplantation. | 1998 | Clin Transplant | pmid:9642520 |
| Gabe SM et al. | The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans. | 1998 | Gastroenterology | pmid:9649460 |
| Canzanello VJ et al. | Late hypertension after liver transplantation: a comparison of cyclosporine and tacrolimus (FK 506). | 1998 | Liver Transpl Surg | pmid:9649648 |
| Friberg H et al. | Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. | 1998 | J. Neurosci. | pmid:9651198 |
| Tarumi K et al. | The plasma FK506-binding protein 12 level is related to acute cellular rejection in small bowel transplantation. | 1998 | Immunopharmacol Immunotoxicol | pmid:9653668 |
| Kommers T et al. | Regulation of the phosphorylation of glial fibrillary acidic protein (GFAP) by glutamate and calcium ions in slices of immature rat spinal cord: comparison with immature hippocampus. | 1998 | Neurosci. Lett. | pmid:9654363 |
| Cetinkale O et al. | Involvement of neutrophils in ischemia-reperfusion injury of inguinal island skin flaps in rats. | 1998 | Plast. Reconstr. Surg. | pmid:9655420 |
| Matsui H et al. | [Physiological role of calcineurin in central nervous system]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9655961 |
| Tamura K | [Multiple actions of tacrolimus and cyclosporin A as specific inhibitors of calcineurin]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9655970 |
| Morozumi K et al. | [Current topics of the rejection pathology in human renal allografts]. | 1998 | Hinyokika Kiyo | pmid:9656109 |
| Nishioka T et al. | [Is tacrolimus effective for ongoing renal allograft rejection?]. | 1998 | Hinyokika Kiyo | pmid:9656112 |
| Sasa H et al. | Hepatic extraction of tacrolimus in rats with experimental liver diseases. | 1998 | Biol. Pharm. Bull. | pmid:9657047 |
| Le Bihan S et al. | Calcium/calmodulin kinase inhibitors and immunosuppressant macrolides rapamycin and FK506 inhibit progestin- and glucocorticosteroid receptor-mediated transcription in human breast cancer T47D cells. | 1998 | Mol. Endocrinol. | pmid:9658403 |
| Fujino T et al. | The immunosuppressive compound FK506 does not affect expulsion of Echinostoma trivolvis in C3H mice. | 1998 | Parasitol. Res. | pmid:9660146 |
| McBride WJ et al. | Allogeneic fetal intestinal transplantation with FK506 immunosuppression. | 1998 | J. Pediatr. Surg. | pmid:9660232 |
| Bader G et al. | Reduction of cyclosporine-induced gingival overgrowth following a change to tacrolimus. A case history involving a liver transplant patient. | 1998 | J. Periodontol. | pmid:9660343 |
| Tsujikawa A et al. | Tacrolimus (FK506) attenuates leukocyte accumulation after transient retinal ischemia. | 1998 | Stroke | pmid:9660400 |
| Lai MM et al. | Cain, a novel physiologic protein inhibitor of calcineurin. | 1998 | J. Biol. Chem. | pmid:9660798 |
| Nagayasu T et al. | Expression of proliferating cell nuclear antigen in bronchial epithelium after lung transplantation in the rat. | 1998 | J. Heart Lung Transplant. | pmid:9662091 |
| Stockwell BR and Schreiber SL | TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins. | 1998 | Chem. Biol. | pmid:9662508 |
| Kokado Y et al. | Low-dose tacrolimus (FK506)-based immunosuppressive protocol in living donor renal transplantation. | 1998 | Transpl. Int. | pmid:9664945 |
| Hauser IA and Neumayer HN | Tacrolimus and cyclosporine efficacy in high-risk kidney transplantation. European Multicentre Tacrolimus (FK506) Renal Study Group. | 1998 | Transpl. Int. | pmid:9664948 |
| Morris-Stiff G et al. | Conversion of renal transplant recipients from cyclosporin to low-dose tacrolimus for refractory rejection. | 1998 | Transpl. Int. | pmid:9664949 |
| Morris-Stiff G et al. | Conversion of renal transplant recipients from cyclosporin (neoral) to tacrolimus (prograf) for haemolytic uraemic syndrome. | 1998 | Transpl. Int. | pmid:9664954 |
| Kyo M et al. | Morphological findings in non-episode biopsies of kidney transplant allografts treated with FK506 or cyclosporine. | 1998 | Transpl. Int. | pmid:9664955 |
| Hernández-Herrera G et al. | Tacrolimus rescue therapy for cyclosporine-induced nephrotoxicity. | 1998 | Transpl. Int. | pmid:9664956 |
| Margarit C et al. | Efficacy and safety of oral low-dose tacrolimus treatment in liver transplantation. | 1998 | Transpl. Int. | pmid:9664992 |
| Pou L et al. | Influence of posttransplant time on dose and concentration of tacrolimus in liver transplant patients. | 1998 | Transpl. Int. | pmid:9664994 |
| Reggiani P et al. | Rescue FK506 early conversion for refractory rejection after pediatric liver transplantation: experience in 20 children. | 1998 | Transpl. Int. | pmid:9664995 |
| Jara P et al. | Tacrolimus for steroid-resistant liver rejection in children. | 1998 | Transpl. Int. | pmid:9664996 |
| Horimoto H et al. | Transplantation tolerance by a combined therapy with sulfatide, anti-LFA-1/ICAM-1 monoclonal antibodies and FK506 in rat cardiac transplantation. | 1998 | Transpl. Int. | pmid:9665003 |
| Charco R et al. | Early use of tacrolimus as rescue therapy for refractory liver allograft rejection. | 1998 | Transpl. Int. | pmid:9665004 |
| Zhang JG et al. | Differential effects of cyclosporin A and tacrolimus on the production of TGF-beta: implications for the development of obliterative bronchiolitis after lung transplantation. | 1998 | Transpl. Int. | pmid:9665007 |
| Peter C et al. | Does tacrolimus cause more severe anemia than cyclosporine A in children after renal transplantation? | 1998 | Transpl. Int. | pmid:9665008 |
| Morris-Stiff G et al. | Prospective randomised study comparing tacrolimus (Prograf) and cyclosporin (Neoral) as primary immunosuppression in cadaveric renal transplants at a single institution: interim report of the first 80 cases. | 1998 | Transpl. Int. | pmid:9665010 |
| Romero E et al. | [Tacrolimus and hypertrophic cardiomyopathy]. | 1998 | Med Clin (Barc) | pmid:9666425 |
| Horigome A et al. | Tacrolimus-induced apoptosis and its prevention by interleukins in mitogen-activated human peripheral-blood mononuclear cells. | 1998 | Immunopharmacology | pmid:9667420 |
| Takamatsu Y et al. | IL-13 production by peripheral blood mononuclear cells from patients with atopic dermatitis. | 1998 | Dermatology (Basel) | pmid:9669111 |
| Gross A et al. | Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. | 1998 | EMBO J. | pmid:9670005 |
| Polak J et al. | Primary pulmonary hypertension: pathologist as patient. | 1998 May-Jun | J R Coll Physicians Lond | pmid:9670148 |
| Trindade E et al. | Use of granulocyte macrophage colony stimulating factor in children after orthotopic liver transplantation. | 1998 | J. Hepatol. | pmid:9672183 |