tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Hypercalcemia D006934 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Whalen HR et al. High Intrapatient Tacrolimus Variability Is Associated With Worse Outcomes in Renal Transplantation Using a Low-Dose Tacrolimus Immunosuppressive Regime. 2017 Transplantation pmid:26950724
Varshosaz J et al. Physicochemical, Pharmacodynamic and Pharmacokinetic Characterization of Soluplus Stabilized Nanosuspension of Tacrolimus. 2017 Curr Drug Deliv pmid:27697037
Savaj S et al. Irreversible Lesions of Tacrolimus-induced Posterior Reversible Leukoencephalopathy Syndrome. 2017 Iran J Kidney Dis pmid:29190599
Cheung AY et al. Probable Donor-Derived Cytomegalovirus Disease After Keratolimbal Allograft Transplantation. 2017 Cornea pmid:28614157
Krenzien F et al. Age-Dependent Metabolic and Immunosuppressive Effects of Tacrolimus. 2017 Am. J. Transplant. pmid:27754593
Zidan AS Taste-masked tacrolimus-phospholipid nanodispersions: dissolution enhancement, taste masking and reduced gastric complications. 2017 Pharm Dev Technol pmid:26811031
Weir MR et al. Long-term Follow-up of Kidney Transplant Recipients in the Spare-the-Nephron-Trial. 2017 Transplantation pmid:26950714
Gao L et al. Synergistic Effects of Tacrolimus and Azoles against Exophiala dermatitidis. 2017 Antimicrob. Agents Chemother. pmid:28923863
Ginocchio L et al. Refractory Ulcerated Necrobiosis Lipoidica: Closure of a Difficult Wound with Topical Tacrolimus. 2017 Adv Skin Wound Care pmid:28914682
Ueno P et al. Wound Healing Complications in Kidney Transplant Recipients Receiving Everolimus. 2017 Transplantation pmid:27490418
Berntsen HF et al. The fungal neurotoxin penitrem A induces the production of reactive oxygen species in human neutrophils at submicromolar concentrations. 2017 Toxicology pmid:29037868
Jouve T et al. New formulations of tacrolimus and prevention of acute and chronic rejections in adult kidney-transplant recipients. 2017 Expert Opin Drug Saf pmid:28494654
Koo K et al. Beyond monotherapy: a systematic review on creative strategies in topical therapy of psoriasis. 2017 J Dermatolog Treat pmid:28481664
Seo SR et al. Disrupted Skin Barrier is Associated with Burning Sensation after Topical Tacrolimus Application in Atopic Dermatitis. 2017 Acta Derm. Venereol. pmid:28512670
Shen CL et al. Tacrolimus Blood Level Fluctuation Predisposes to Coexisting BK Virus Nephropathy and Acute Allograft Rejection. 2017 Sci Rep pmid:28512328
Wolfshohl JA et al. Improvement of erythema dyschromicum perstans using a combination of the 1,550-nm erbium-doped fractionated laser and topical tacrolimus ointment. 2017 Lasers Surg Med pmid:27552666
Kizilbash SJ et al. Infection rates in tacrolimus versus cyclosporine-treated pediatric kidney transplant recipients on a rapid discontinuation of prednisone protocol: 1-year analysis. 2017 Pediatr Transplant pmid:28371243
Khimani F et al. Predictors of overall survival among patients treated with sirolimus/tacrolimus vs methotrexate/tacrolimus for GvHD prevention. 2017 Bone Marrow Transplant. pmid:28368376
Gard L et al. A delicate balance between rejection and BK polyomavirus associated nephropathy; A retrospective cohort study in renal transplant recipients. 2017 PLoS ONE pmid:28609473
Wang J et al. Comparative proteomic and metabolomic analysis of Streptomyces tsukubaensis reveals the metabolic mechanism of FK506 overproduction by feeding soybean oil. 2017 Appl. Microbiol. Biotechnol. pmid:28175948
Vanhove T et al. Effect of ABCB1 diplotype on tacrolimus disposition in renal recipients depends on CYP3A5 and CYP3A4 genotype. 2017 Pharmacogenomics J. pmid:27378609
David-Neto E et al. Longitudinal Pharmacokinetics of Tacrolimus in Elderly Compared With Younger Recipients in the First 6 Months After Renal Transplantation. 2017 Transplantation pmid:27482958
Lawrance IC et al. Efficacy of Rectal Tacrolimus for Induction Therapy in Patients With Resistant Ulcerative Proctitis. 2017 Clin. Gastroenterol. Hepatol. pmid:28286194
Ikeda K et al. Intestinal perforation due to hemorrhagic Cytomegalovirus enteritis in a patient with severe uncontrolled lupus nephritis: a case and review of the literature. 2017 Rheumatol. Int. pmid:28283734
Toyota H et al. Process optimization by use of design of experiments: Application for liposomalization of FK506. 2017 Eur J Pharm Sci pmid:28279762
Morita M et al. The onset risk of carcinoma in patients continuing tacrolimus topical treatment for oral lichen planus: a case report. 2017 Odontology pmid:27368962
Ribero S and Borradori L Re: risk of malignancy and systemic absorption after application of topical tacrolimus in oral lichen planus. 2017 J Eur Acad Dermatol Venereol pmid:27291784
Hamada T et al. Phenotypic analysis of circulating T-cell subset and its association with burden of skin disease in patients with chronic actinic dermatitis: a hematologic and clinicopathologic study of 20 subjects. 2017 Int. J. Dermatol. pmid:28176301
Piotti G et al. Once-daily prolonged-release tacrolimus formulations for kidney transplantation: what the nephrologist needs to know. 2017 J. Nephrol. pmid:27206763
Ak K et al. Tacrolimus-Eluting Suture Inhibits Neointimal Hyperplasia: An Experimental In Vivo Study in Rats. 2017 Eur J Vasc Endovasc Surg pmid:28065442
Ma TK et al. Therapeutic drug monitoring of once-daily tacrolimus (Advagraf) in a gastrectomized kidney transplant recipient. 2017 Nephrology (Carlton) pmid:28064453
Schifferer M et al. Reversible Chemical Dimerization by rCD1. 2017 Meth. Enzymol. pmid:28063490
Kirresh T et al. Development and validation of a liquid chromatography-mass spectrometric assay for simultaneous determination of tacrolimus and 13-O-desmethyl tacrolimus in rat kidney tissue. 2017 J Pharm Biomed Anal pmid:28063333
Percy C et al. Impact of Acute Infection Requiring Hospitalization on Tacrolimus Blood Levels in Kidney Transplant Recipients. 2017 Transplant. Proc. pmid:29149962
Obaidat RM et al. Using Supercritical Fluid Technology (SFT) in Preparation of Tacrolimus Solid Dispersions. 2017 AAPS PharmSciTech pmid:27116202
Krämer BK et al. Efficacy of Prolonged- and Immediate-release Tacrolimus in Kidney Transplantation: A Pooled Analysis of Two Large, Randomized, Controlled Trials. 2017 Transplant. Proc. pmid:29149958
de Menezes AF et al. Pharmacologic Treatment of Vitiligo in Children and Adolescents: A Systematic Review. 2017 Pediatr Dermatol pmid:27878842
Taber DJ et al. A Comparative Effectiveness Analysis of Early Steroid Withdrawal in Black Kidney Transplant Recipients. 2017 Clin J Am Soc Nephrol pmid:27979979
Watanabe M et al. Successful treatment of calcineurin inhibitor-induced pain syndrome with acute graft versus host disease by switching calcineurin inhibitors followed by pregabalin. 2017 Ann. Hematol. pmid:28508935
Flahault A et al. Clinical impact of the CYP3A5 6986A>G allelic variant on kidney transplantation outcomes. 2017 Pharmacogenomics pmid:27977332
Khan SA et al. Improvement in baroreflex control of renal sympathetic nerve activity in obese Sprague Dawley rats following immunosuppression. 2017 Acta Physiol (Oxf) pmid:28456134
Tron C et al. Tacrolimus: Does direct glucuronidation matter? An analytical and pharmacological perspective. 2017 Pharmacol. Res. pmid:28366836
Wan T et al. Dual roles of TPGS based microemulsion for tacrolimus: Enhancing the percutaneous delivery and anti-psoriatic efficacy. 2017 Int J Pharm pmid:28629978
Tremblay S and Alloway RR Clinical Evaluation of Modified Release and Immediate Release Tacrolimus Formulations. 2017 AAPS J pmid:28717926
Ganschow R et al. Everolimus and reduced calcineurin inhibitor therapy in pediatric liver transplant recipients: Results from a multicenter, prospective study. 2017 Pediatr Transplant pmid:28714558
Bremer S et al. NFAT-regulated cytokine gene expression during tacrolimus therapy early after renal transplantation. 2017 Br J Clin Pharmacol pmid:28686294
Rivosecchi RM et al. Effects of Isavuconazole on the Plasma Concentrations of Tacrolimus among Solid-Organ Transplant Patients. 2017 Antimicrob. Agents Chemother. pmid:28674051
Hasegawa J et al. Preemptive anti-cytomegalovirus therapy in high-risk (donor-positive, recipient-negative cytomegalovirus serostatus) kidney transplant recipients. 2017 Int. J. Infect. Dis. pmid:28986314
Olariu R et al. Intra-graft injection of tacrolimus promotes survival of vascularized composite allotransplantation. 2017 J. Surg. Res. pmid:28985877
Tao X et al. Long-term efficacy and side effects of low-dose tacrolimus for the treatment of Myasthenia Gravis. 2017 Neurol. Sci. pmid:27873026