| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ishida A et al. | Clinical factors influencing posttransfusion platelet increment in patients undergoing hematopoietic progenitor cell transplantation--a prospective analysis. | 1998 | Transfusion | pmid:9738624 |
| Allen C et al. | Polycaprolactone-b-poly(ethylene oxide) block copolymer micelles as a novel drug delivery vehicle for neurotrophic agents FK506 and L-685,818. | 1998 Sep-Oct | Bioconjug. Chem. | pmid:9736490 |
| Hodak SP et al. | QT prolongation and near fatal cardiac arrhythmia after intravenous tacrolimus administration: a case report. | 1998 | Transplantation | pmid:9734501 |
| Wiesner RH | A long-term comparison of tacrolimus (FK506) versus cyclosporine in liver transplantation: a report of the United States FK506 Study Group. | 1998 | Transplantation | pmid:9734494 |
| Sussman MA et al. | Prevention of cardiac hypertrophy in mice by calcineurin inhibition. | 1998 | Science | pmid:9733519 |
| Cogill JL et al. | Evaluation of the tacrolimus II microparticle enzyme immunoassay (MEIA II) in liver and renal transplant recipients. | 1998 | Clin. Chem. | pmid:9732981 |
| Kawahara K et al. | Tracheal transplantation for carinal reconstruction in dogs. | 1998 | J. Thorac. Cardiovasc. Surg. | pmid:9731780 |
| Meiser BM et al. | Single-center randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of acute myocardial rejection. | 1998 | J. Heart Lung Transplant. | pmid:9730427 |
| Reichart B et al. | European Multicenter Tacrolimus (FK506) Heart Pilot Study: one-year results--European Tacrolimus Multicenter Heart Study Group. | 1998 | J. Heart Lung Transplant. | pmid:9730426 |
| Horning NR et al. | Tacrolimus therapy for persistent or recurrent acute rejection after lung transplantation. | 1998 | J. Heart Lung Transplant. | pmid:9730424 |
| Winter C et al. | MAP kinase phosphatase 1 is expressed and enhanced by FK506 in surviving mamillary, but not degenerating nigral neurons following axotomy. | 1998 | Brain Res. | pmid:9729383 |
| Gammie JS et al. | A partial conditioning strategy for achieving mixed chimerism in the rat: tacrolimus and anti-lymphocyte serum substantially reduce the minimum radiation dose for engraftment. | 1998 | Exp. Hematol. | pmid:9728927 |
| Snyder SH et al. | Immunophilins in the nervous system. | 1998 | Neuron | pmid:9728910 |
| Garcia-Cozar FJ et al. | Two-site interaction of nuclear factor of activated T cells with activated calcineurin. | 1998 | J. Biol. Chem. | pmid:9727000 |
| Reddy SS and Holley JL | Nocardiosis in a recently transplanted renal patient. | 1998 | Clin. Nephrol. | pmid:9725785 |
| Thielke J et al. | Pharmacokinetics of tacrolimus and cyclosporine in short-bowel syndrome. | 1998 | Liver Transpl Surg | pmid:9724482 |
| Herzberg GZ et al. | Usefulness of tacrolimus versus cyclosporine after pediatric heart transplantation. | 1998 | Am. J. Cardiol. | pmid:9723652 |
| Miyata Y et al. | Development of xenogeneic microchimerism correlated with graft outcome in hamster-to-rat heart xenotransplantation. | 1998 | Transplant. Proc. | pmid:9723548 |
| Hanack U et al. | Is there a different impact of cyclosporine versus tacrolimus on delayed graft function after kidney transplantation? | 1998 | Transplant. Proc. | pmid:9723477 |
| Fritsche L et al. | Late conversion to mycophenolate mofetil for chronic deterioration of renal allograft function. | 1998 | Transplant. Proc. | pmid:9723451 |
| Pirsch JD | Mycophenolate mofetil, tacrolimus, Neoral: from clinical trials to the clinic. | 1998 | Transplant. Proc. | pmid:9723448 |
| Xu M et al. | FTY720 compares with FK 506 as rescue therapy in rat heterotopic cardiac transplantation. | 1998 | Transplant. Proc. | pmid:9723447 |
| Yonan NA et al. | Tracheal allograft transplantation in rats: the role of immunosuppressive agents in development of obliterative airway disease. | 1998 | Transplant. Proc. | pmid:9723443 |
| Perego C et al. | Study of the immunosuppressive effect of SMS 201-995 and its synergic action with FK 506. | 1998 | Transplant. Proc. | pmid:9723434 |
| Jonas S et al. | Five-year follow-up of tacrolimus as primary immunosuppressant after liver transplantation. | 1998 | Transplant. Proc. | pmid:9723433 |
| Busuttil RW and Holt CD | Tacrolimus is superior to cyclosporine in liver transplantation. | 1998 | Transplant. Proc. | pmid:9723432 |
| Vanrenterghem Y | Tacrolimus (FK 506) in kidney transplantation. | 1998 | Transplant. Proc. | pmid:9723431 |
| Halloran PF et al. | Calcineurin and the biological effect of cyclosporine and tacrolimus. | 1998 | Transplant. Proc. | pmid:9723430 |
| Otto C et al. | Selective immunosuppression with FK 506, anti-IL-2R, and anti-ICAM-1 monoclonal antibodies: contrasting effects after liver and small bowel transplantation in rats. | 1998 | Transplant. Proc. | pmid:9723426 |
| Kohnle M et al. | Conversion to tacrolimus in cyclosporin A treated patients with gum hyperplasia. | 1998 | Transplant. Proc. | pmid:9723413 |
| Atillasoy E et al. | Cholesterol levels long-term after liver transplant. | 1998 | Transplant. Proc. | pmid:9723387 |
| Varghese Z et al. | Oxidizability of low-density lipoproteins from Neoral and tacrolimus-treated renal transplant patients. | 1998 | Transplant. Proc. | pmid:9723384 |
| Donadio C et al. | Tubular damage and impairment of renal function in transplanted kidneys. | 1998 | Transplant. Proc. | pmid:9723381 |
| Burrows L et al. | Conversion to tacrolimus to ameliorate cyclosporine toxicity in kidney recipients. | 1998 | Transplant. Proc. | pmid:9723378 |
| Yoshimura R et al. | Hepatocyte growth factor: a sensitive indicator for CsA-induced nephropathy. | 1998 | Transplant. Proc. | pmid:9723373 |
| Curtis JJ | Posttransplant hypertension. | 1998 | Transplant. Proc. | pmid:9723370 |
| Falkenstein K and Dunn S | Tacrolimus to cyclosporine microemulsion formulation conversion in the pediatric liver transplant patient. | 1998 | Transplant. Proc. | pmid:9723354 |
| Ettenger RB | New immunosuppressive agents in pediatric renal transplantation. | 1998 | Transplant. Proc. | pmid:9723350 |
| Berweck S et al. | Clinical use of the euglycemic hyperinsulinemic clamp for diagnosis of tacrolimus-induced insulin resistance after combined pancreas-kidney transplantation. | 1998 | Transplant. Proc. | pmid:9723345 |
| Behr TM et al. | Incidence of humoral rejection in heart transplant recipients treated with tacrolimus or cyclosporine A. | 1998 | Transplant. Proc. | pmid:9723333 |
| Lang M et al. | Combined liver-kidney transplantation: long-term follow-up in 18 patients. | 1998 | Transplant. Proc. | pmid:9723313 |
| Lagget M et al. | Disappearance of diabetes mellitus after conversion from FK 506 to Neoral in two liver transplanted patients. | 1998 | Transplant. Proc. | pmid:9723312 |
| Gridelli B et al. | Frequency of switch from cyclosporine to FK 506 before and after Neoral use in pediatric liver transplantation. | 1998 | Transplant. Proc. | pmid:9723311 |
| Alberti D et al. | Conversion from tacrolimus to microemulsion formulation of cyclosporine in pediatric liver transplantation. | 1998 | Transplant. Proc. | pmid:9723310 |
| Reggiani P et al. | Reduced acute rejection after liver transplantation with Neoral-based double immunosuppression. | 1998 | Transplant. Proc. | pmid:9723308 |
| Rayes N et al. | Distribution of lymphocyte subtypes in liver transplant recipients with viral reinfection or de novo malignancy. | 1998 | Transplant. Proc. | pmid:9723303 |
| Peeters P et al. | Economic evaluation of Neoral versus Sandimmune maintenance therapy for de novo liver transplant patients: results from an International Randomized Controlled Trial. Milton Study Group. | 1998 | Transplant. Proc. | pmid:9723301 |
| Van Buren D et al. | Impact of Sandimmune, Neoral, and Prograf on rejection incidence and renal function in primary liver transplant recipients. | 1998 | Transplant. Proc. | pmid:9723299 |
| McMaster P et al. | Liver transplantation: changing goals in immunosuppression. | 1998 | Transplant. Proc. | pmid:9723295 |
| Levy GA | Neoral is superior to FK 506 in liver transplantation. | 1998 | Transplant. Proc. | pmid:9723293 |
| Budde K et al. | Long-term outcome of tacrolimus rescue therapy in late rejection after renal transplantation. | 1998 | Transplant. Proc. | pmid:9723280 |
| Armenti VT et al. | Pregnancy outcomes in female renal transplant recipients. | 1998 | Transplant. Proc. | pmid:9723259 |
| Keown PA and Primmett DR | Cyclosporine: the principal immunosuppressant for renal transplantation. | 1998 | Transplant. Proc. | pmid:9723252 |
| Kahan BD | High variability of drug exposure: a biopharmaceutic risk factor for chronic rejection. | 1998 | Transplant. Proc. | pmid:9723224 |
| Calandra S | Sinus arrest during tacrolimus treatment: was the QT interval prolonged? | 1998 | Transplantation | pmid:9721813 |
| Glicklich D et al. | Chronic renal allograft rejection: no response to mycophenolate mofetil. | 1998 | Transplantation | pmid:9721811 |
| Terakura M et al. | Lymphoid/nonlymphoid compartmentalization of donor leukocyte chimerism in rat recipients of heart allografts, with or without adjunct bone marrow. | 1998 | Transplantation | pmid:9721804 |
| Gruessner RW et al. | Mycophenolate mofetil in pancreas transplantation. | 1998 | Transplantation | pmid:9721799 |
| Soldin SJ | Role of immunophilins in therapeutic drug monitoring of immunosuppressive drugs. | 1998 | Clin. Biochem. | pmid:9721438 |
| Oellerich M et al. | Therapeutic drug monitoring of cyclosporine and tacrolimus. Update on Lake Louise Consensus Conference on cyclosporin and tacrolimus. | 1998 | Clin. Biochem. | pmid:9721427 |
| Srivastava M et al. | Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child. | 1998 | Gastroenterology | pmid:9721172 |
| Yang X et al. | Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. | 1998 | Science | pmid:9721101 |
| Jacobson P et al. | Tacrolimus: a new agent for the prevention of graft-versus-host disease in hematopoietic stem cell transplantation. | 1998 | Bone Marrow Transplant. | pmid:9720734 |
| Tao HR | FK506 inhibits severe graft-versus-host disease without mediating the involvement of perforin and granzyme B. | 1998 | Hokkaido Igaku Zasshi | pmid:9719949 |
| Fukuda K et al. | cFKBP/SMAP; a novel molecule involved in the regulation of smooth muscle differentiation. | 1998 | Development | pmid:9716519 |
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| Iizuka K et al. | InsP3, but not novel Ca2+ releasers, contributes to agonist-initiated contraction in rabbit airway smooth muscle. | 1998 | J. Physiol. (Lond.) | pmid:9714870 |
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| Ruetz S | Yeast secretory vesicle system for expression and functional characterization of P-glycoproteins. | 1998 | Meth. Enzymol. | pmid:9711569 |
| White MH et al. | Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia. | 1998 | Clin. Infect. Dis. | pmid:9709879 |
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| Stone JH et al. | Outcome of renal transplantation in ninety-seven cyclosporine-era patients with systemic lupus erythematosus and matched controls. | 1998 | Arthritis Rheum. | pmid:9704643 |
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| Garg UC et al. | Comparison of the Abbott IMx Tacrolimus I and Tacrolimus II assays. | 1998 | Clin. Chem. | pmid:9702984 |
| Gruessner RW et al. | Donor-specific portal blood transfusion in intestinal transplantation: a prospective, preclinical large animal study. | 1998 | Transplantation | pmid:9701258 |
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| Rejto PA and Verkhivker GM | Molecular anchors with large stability gaps ensure linear binding free energy relationships for hydrophobic substituents. | 1998 | Pac Symp Biocomput | pmid:9697196 |
| Mihatsch MJ et al. | The side-effects of ciclosporine-A and tacrolimus. | 1998 | Clin. Nephrol. | pmid:9696431 |
| Moriwaki A et al. | An immunosuppressant, FK506, protects against neuronal dysfunction and death but has no effect on electrographic and behavioral activities induced by systemic kainate. | 1998 | Neuroscience | pmid:9692722 |
| Ding JM et al. | A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock. | 1998 | Nature | pmid:9690474 |
| Kilmartin DJ et al. | Tacrolimus (FK506) in failed cyclosporin A therapy in endogenous posterior uveitis. | 1998 | Ocul. Immunol. Inflamm. | pmid:9689640 |
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| Medh RD et al. | Agonist-specific modulation of glucocorticoid receptor-mediated transcription by immunosuppressants. | 1998 | Mol. Cell. Endocrinol. | pmid:9685211 |
| Peces R et al. | Alloimmune haemolytic anaemia resulting from anti-A and anti-B antibody induced by group O graft in renal transplant recipients. | 1998 | Nephrol. Dial. Transplant. | pmid:9681751 |
| Grupp C et al. | Haemolytic uraemic syndrome (HUS) during treatment with cyclosporin A after renal transplantation--is tacrolimus the answer? | 1998 | Nephrol. Dial. Transplant. | pmid:9681701 |
| Hultsch T et al. | Direct evidence that FK506 inhibition of FcepsilonRI-mediated exocytosis from RBL mast cells involves calcineurin. | 1998 | Arch. Dermatol. Res. | pmid:9681677 |
| Van Leent EJ et al. | Effectiveness of the ascomycin macrolactam SDZ ASM 981 in the topical treatment of atopic dermatitis. | 1998 | Arch Dermatol | pmid:9681343 |
| Denesyuk AI et al. | Analogous conformations of both binding and effector regions in cyclosporin A, FK506 and rapamycin. | 1998 | Comput. Chem. | pmid:9680690 |
| Sanchez-Campos S et al. | Cholestasis and alterations of glutathione metabolism induced by tacrolimus (FK506) in the rat. | 1998 | Transplantation | pmid:9679826 |
| Fisher NC et al. | Chronic renal failure following liver transplantation: a retrospective analysis. | 1998 | Transplantation | pmid:9679823 |
| Onuma H et al. | A calcineurin inhibitor, FK506, blocks voltage-gated calcium channel-dependent LTP in the hippocampus. | 1998 | Neurosci. Res. | pmid:9678635 |
| Salowe SP and Hermes JD | Competitive and slow-binding inhibition of calcineurin by drug x immunophilin complexes. | 1998 | Arch. Biochem. Biophys. | pmid:9675023 |
| Yardin C et al. | FK506 antagonizes apoptosis and c-jun protein expression in neuronal cultures. | 1998 | Neuroreport | pmid:9674596 |