| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moncourier M et al. | [Granulomatous periocular eruption]. | Ann Dermatol Venereol | pmid:28410769 | |
| Soda M et al. | Association Between Tacrolimus Pharmacokinetics and Cytochrome P450 3A5 and Multidrug Resistance Protein 1 Exon 21 Polymorphisms. | Transplant. Proc. | pmid:28736028 | |
| Lian Y et al. | Suppression of Delayed Xenograft Rejection by Resveratrol in a Hamster-to-Rat Cardiac Transplantation Model. | Transplant. Proc. | pmid:28736027 | |
| Loredana Asztalos M et al. | Recurrent dermatitis and dermal hypersensitivity following a jellyfish sting: a case report and review of literature. | Pediatr Dermatol | pmid:24495001 | |
| Mlinšek G et al. | The role of single nucleotide polymorphisms of CYP3A and ABCB1 on tacrolimus predose concentration in kidney transplant recipients. | Clin. Nephrol. | pmid:28655393 | |
| Lentine KL et al. | Variation in Comedication Use According to Kidney Transplant Immunosuppressive Regimens: Application of Integrated Registry and Pharmacy Claims Data. | Transplant. Proc. | pmid:26915843 | |
| Zhao DQ et al. | Sirolimus-Based Immunosuppressive Regimens in Renal Transplantation: A Systemic Review. | Transplant. Proc. | pmid:26915834 | |
| Liendo VL et al. | Topical tacrolimus for the treatment of severe allergic keratoconjunctivitis in children. | Arq Bras Oftalmol | pmid:28954018 | |
| Johnson JL et al. | Pyoderma gangrenosum associated with an aseptic splenic abscess in a patient with neurofibromatosis. | Pediatr Dermatol | pmid:23535023 | |
| Moreno Gonzales M et al. | Sublingual Tacrolimus in Liver Transplantation: A Valid Option? | Transplant. Proc. | pmid:27569953 | |
| pmid:25901935 | ||||
| Sahu MK et al. | High blood tacrolimus and hyperkalemia in a heart transplant patient. | Ann Card Anaesth | pmid:28393798 | |
| Lasa J and Olivera P | EFFICACY OF TACROLIMUS FOR INDUCTION OF REMISSION IN PATIENTS WITH MODERATE-TO-SEVERE ULCERATIVE COLITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. | Arq Gastroenterol | pmid:28327826 | |
| Lima RS et al. | Granuloma faciale: a good therapeutic response with the use of topical tacrolimus. | An Bras Dermatol | pmid:26560220 | |
| Kubiça TF et al. | Antifungal activities of tacrolimus in combination with antifungal agents against fluconazole-susceptible and fluconazole-resistant Trichosporon asahii isolates. | Braz J Infect Dis | pmid:27697432 | |
| pmid: | ||||
| Kabuto M et al. | Annular lupus erythematosus profundus. | Eur J Dermatol | pmid:25115404 | |
| pmid:8986461 | ||||
| Forns X et al. | Efficacy of telaprevir-based therapy in stable liver transplant patients with chronic genotype 1 hepatitis C. | Ann Hepatol | pmid:27236150 | |
| pmid:22935463 | ||||
| pmid:21079467 | ||||
| pmid:28951508 | ||||
| Tan GF et al. | Anogenital epidermolytic acanthomas: effective treatment of pruritus with 0.1% tacrolimus ointment. | Dermatol Ther | pmid:24703270 | |
| Collier DS et al. | FK-506 in experimental renal allografts. | 1987 | Transplant. Proc. | pmid:2445063 |
| First International Workshop on FK-506. A potential breakthrough in immunosuppression. Proceedings. | 1987 | Transplant. Proc. | pmid:2445066 | |
| Tanaka H et al. | Physicochemical properties of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. | 1987 | Transplant. Proc. | pmid:2445067 |
| Honbo T et al. | The oral dosage form of FK-506. | 1987 | Transplant. Proc. | pmid:2445068 |
| Venkataramanan R et al. | Biopharmaceutical aspects of FK-506. | 1987 | Transplant. Proc. | pmid:2445070 |
| Kino T et al. | Effect of FK-506 on human mixed lymphocyte reaction in vitro. | 1987 | Transplant. Proc. | pmid:2445071 |
| Goto T et al. | Discovery of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. | 1987 | Transplant. Proc. | pmid:2445072 |
| Zeevi A et al. | Immunosuppressive effect of FK-506 on in vitro lymphocyte alloactivation: synergism with cyclosporine A. | 1987 | Transplant. Proc. | pmid:2445073 |
| Sanghvi A et al. | FK-506 enhances cyclosporine uptake by peripheral blood lymphocytes. | 1987 | Transplant. Proc. | pmid:2445074 |
| Ochiai T et al. | Prolongation of canine renal allograft survival by treatment with FK-506. | 1987 | Transplant. Proc. | pmid:2445075 |
| Todo S et al. | Canine kidney transplantation with FK-506 alone or in combination with cyclosporine and steroids. | 1987 | Transplant. Proc. | pmid:2445076 |
| Collier DS et al. | Kidney transplantation in the dog receiving FK-506. | 1987 | Transplant. Proc. | pmid:2445077 |
| Calne R et al. | Observations about FK-506 in primates. | 1987 | Transplant. Proc. | pmid:2445078 |
| Todo S et al. | Orthotopic liver transplantation in dogs receiving FK-506. | 1987 | Transplant. Proc. | pmid:2445079 |
| Lim SM et al. | Heterotopic heart transplantation in the rat receiving FK-506. | 1987 | Transplant. Proc. | pmid:2445080 |
| Murase N et al. | Heterotopic heart transplantation in the rat receiving FK-506 alone or with cyclosporine. | 1987 | Transplant. Proc. | pmid:2445081 |
| Makowka L et al. | The effect of FK-506 on hyperacute rejection in presensitized rats. | 1987 | Transplant. Proc. | pmid:2445082 |
| Ochiai T et al. | Effects of FK-506 on xenotransplantation of the heart and skin in a mouse-rat combination. | 1987 | Transplant. Proc. | pmid:2445083 |
| Nalesnik MA et al. | Toxicology of FK-506 in the Lewis rat. | 1987 | Transplant. Proc. | pmid:2445084 |
| Ochiai T et al. | Histopathologic studies in renal transplant recipient dogs receiving treatment with FK-506. | 1987 | Transplant. Proc. | pmid:2445085 |
| Thiru S et al. | Pathological studies in canine and baboon renal allograft recipients immunosuppressed with FK-506. | 1987 | Transplant. Proc. | pmid:2445086 |
| Kino T et al. | FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. | 1987 | J. Antibiot. | pmid:2445721 |
| Kino T et al. | FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. | 1987 | J. Antibiot. | pmid:2445722 |
| Ochiai T et al. | Studies of the effects of FK506 on renal allografting in the beagle dog. | 1987 | Transplantation | pmid:2447688 |
| Ochiai T et al. | Studies of the induction and maintenance of long-term graft acceptance by treatment with FK506 in heterotopic cardiac allotransplantation in rats. | 1987 | Transplantation | pmid:2447689 |
| Ochiai T et al. | Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat. | 1987 | Transplant. Proc. | pmid:2484094 |
| Sawada S et al. | Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation. | 1987 | J. Immunol. | pmid:2442255 |