| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:7756878 | ||||
| pmid: | ||||
| Poehlsgaard J et al. | Visualizing the 16-membered ring macrolides tildipirosin and tilmicosin bound to their ribosomal site. | 2012 | ACS Chem. Biol. | pmid:22563863 |
| Stipkovits L et al. | Efficacy of lasalocid sodium against mycoplasmas (preliminary communication). | 1984 | Acta Vet. Hung. | pmid:6242271 |
| Fodor L et al. | Treatment of calf pneumonia with tilmicosin. | 1993 | Acta Vet. Hung. | pmid:8116500 |
| Er A and Yazar E | Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury. | 2012 | Acta Vet. Hung. | pmid:23160029 |
| Er A et al. | Effects of tylosin on serum cytokine levels in healthy and lipopolysaccharide-treated mice. | 2010 | Acta Vet. Hung. | pmid:20159741 |
| Jensen LB and Aarestrup FM | Regulation of the erm(C) gene in Staphylococci from reservoir with different usage of macrolides. | 2005 | Acta Vet. Scand. | pmid:16261929 |
| Kilpinen S et al. | Efficacy of two low-dose oral tylosin regimens in controlling the relapse of diarrhea in dogs with tylosin-responsive diarrhea: a prospective, single-blinded, two-arm parallel, clinical field trial. | 2014 | Acta Vet. Scand. | pmid:25096196 |
| Kilpinen S et al. | Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial. | 2011 | Acta Vet. Scand. | pmid:21489311 |
| Chemier JA et al. | Trends in microbial synthesis of natural products and biofuels. | 2009 | Adv. Enzymol. Relat. Areas Mol. Biol. | pmid:18990830 |
| Li B et al. | EFFICACY AND SAFETY OF BAN HUANG ORAL LIQUID FOR TREATING BOVINE RESPIRATORY DISEASES. | 2017 | Afr J Tradit Complement Altern Med | pmid:28573221 |
| Itoh Z et al. | Structure-activity relation among macrolide antibiotics in initiation of interdigestive migrating contractions in the canine gastrointestinal tract. | 1985 | Am. J. Physiol. | pmid:3976891 |
| Wittum TE et al. | Haptoglobin response to clinical respiratory tract disease in feedlot cattle. | 1996 | Am. J. Vet. Res. | pmid:8723875 |
| Mendoza J et al. | Concentrations of tilmicosin in mammary gland secretions of dairy cows following subcutaneous administration of one or two doses of an experimental preparation of tilmicosin and its efficacy against intramammary infections caused by Staphylococcus aureus. | 2016 | Am. J. Vet. Res. | pmid:27580103 |
| Fajt VR et al. | Effect of danofloxacin and tilmicosin on body temperatures of beef calves with pneumonia experimentally induced by inoculation with Mannheimia haemolytica. | 2004 | Am. J. Vet. Res. | pmid:15141881 |
| Confer AW et al. | Clinical disease and lung lesions in calves experimentally inoculated with Histophilus somni five days after metaphylactic administration of tildipirosin or tulathromycin. | 2016 | Am. J. Vet. Res. | pmid:27027834 |
| Blondeau JM et al. | Bactericidal effects of various concentrations of enrofloxacin, florfenicol, tilmicosin phosphate, and tulathromycin on clinical isolates of Mannheimia haemolytica. | 2015 | Am. J. Vet. Res. | pmid:26413823 |
| Kim HB et al. | Effects of tylosin administration on C-reactive protein concentration and carriage of Salmonella enterica in pigs. | 2014 | Am. J. Vet. Res. | pmid:24762018 |
| Nagaraja TG et al. | Effects of tylosin on concentrations of Fusobacterium necrophorum and fermentation products in the rumen of cattle fed a high-concentrate diet. | 1999 | Am. J. Vet. Res. | pmid:10490072 |