Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Tracheal Diseases D014133 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Lee WD et al. Tilmicosin-induced bovine neutrophil apoptosis is cell-specific and downregulates spontaneous LTB4 synthesis without increasing Fas expression. 2004 Mar-Apr Vet. Res. pmid:15099497
Cusack PM Effect of mass medication with antibiotics at feedlot entry on the health and growth rate of cattle destined for the Australian domestic market. 2004 Aust. Vet. J. pmid:15088981
Chirase NK et al. Effect of simulated ambient particulate matter exposure on performance, rectal temperature, and leukocytosis of young Spanish goats with or without tilmicosin phosphate. 2004 J. Anim. Sci. pmid:15080345
Dykman LA et al. [Immunogenic properties of the colloidal gold]. 2004 Jan-Feb Izv. Akad. Nauk. Ser. Biol. pmid:15049073
Douthwaite S et al. The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748. 2004 J. Mol. Biol. pmid:15046978
Taniguchi K et al. The role of histidine residues conserved in the putative ATP-binding region of macrolide 2'-phosphotransferase II. 2004 FEMS Microbiol. Lett. pmid:15033229
Karlsson M et al. Further characterization of porcine Brachyspira hyodysenteriae isolates with decreased susceptibility to tiamulin. 2004 J. Med. Microbiol. pmid:15017283
Yildiz S et al. Tylosin does not affect GnRH-induced LH secretion in rams. 2004 Jan-Feb Reprod. Toxicol. pmid:15013072
Jost BH et al. A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes. 2004 Antimicrob. Agents Chemother. pmid:14982756
Paradis MA et al. Efficacy of tilmicosin in the control of experimentally induced Actinobacillus pleuropneumoniae infection in swine. 2004 Can. J. Vet. Res. pmid:14979429
Kumar K et al. Enzyme-linked immunosorbent assay for ultratrace determination of antibiotics in aqueous samples. 2004 Jan-Feb J. Environ. Qual. pmid:14964379
Moretto A et al. Slow release of two antibiotics of veterinary interest from PVA hydrogels. 2004 Farmaco pmid:14751309
Ammida NH et al. Analysis of erythromycin and tylosin in bovine muscle using disposable screen printed electrodes. 2004 Analyst pmid:14737577
Wang J Determination of five macrolide antibiotic residues in honey by LC-ESI-MS and LC-ESI-MS/MS. 2004 J. Agric. Food Chem. pmid:14733491
Mutak S et al. Semisynthetic macrolide antibacterials derived from tylosin. Synthesis and structure-activity relationships of novel desmycosin analogues. 2004 J. Med. Chem. pmid:14711312
Prapasarakul N et al. In vitro susceptibility and a new point mutation associated with tylosin-resistance in Japanese canine intestinal spirochetes. 2003 J. Vet. Med. Sci. pmid:14709813
Thompson TS et al. Determination of lincomycin and tylosin residues in honey using solid-phase extraction and liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. 2003 J Chromatogr A pmid:14661747
Lee HJ and Jin HJ Renaturation of recombinant ErmSF and its refolding behavior. 2003 Mol. Cells pmid:14651260
Montesissa C et al. Metabolism of tilmicosin by rabbit liver microsomes and hepatocytes. 2004 Vet. J. pmid:14623156
Sumbatyan NV et al. Peptide derivatives of antibiotics tylosin and desmycosin, protein synthesis inhibitors. 2003 Biochemistry Mosc. pmid:14616087