| MeSH term | MeSH ID | Detail |
|---|---|---|
| Asthma | D001249 | 52 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Campylobacter Infections | D002169 | 13 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Conjunctivitis, Viral | D003236 | 1 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sura S et al. | Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff. | 2015 | Sci. Total Environ. | pmid:25839178 |
| Li Q et al. | Co-addition of manure increases the dissipation rates of tylosin A and the numbers of resistance genes in laboratory incubation experiments. | 2015 | Sci. Total Environ. | pmid:25958362 |
| Xia X et al. | Proteomic analysis of tylosin-resistant Mycoplasma gallisepticum reveals enzymatic activities associated with resistance. | 2015 | Sci Rep | pmid:26584633 |
| Brown K et al. | Antimicrobial growth promoters modulate host responses in mice with a defined intestinal microbiota. | 2016 | Sci Rep | pmid:27929072 |
| Huwyler U et al. | Efficacy evaluation of the use of oral tilmicosin in pneumonic calves. | 1999 | Schweiz. Arch. Tierheilkd. | pmid:10228400 |
| Greer RT and Ryoo JP | Development of ocular inserts for cattle. | 1987 | Scanning Microsc. | pmid:3616580 |
| Reynaldi FJ et al. | [Binding of tylosin, tilmicosin and oxytetracycline to proteins from honeybees, larvae and beehive products]. | 2010 Oct-Dec | Rev. Argent. Microbiol. | pmid:21229198 |
| Loria GR et al. | In vitro susceptibilities of field isolates of Mycoplasma agalactiae to oxytetracycline, tylosin, enrofloxacin, spiramycin and lincomycin-spectinomycin. | 2003 | Res. Vet. Sci. | pmid:12801456 |
| Prats C et al. | Tylosin depletion from edible pig tissues. | 2002 | Res. Vet. Sci. | pmid:12443694 |
| Timsit E et al. | Effects of nasal instillation of a nitric oxide-releasing solution or parenteral administration of tilmicosin on the nasopharyngeal microbiota of beef feedlot cattle at high-risk of developing respiratory tract disease. | 2017 | Res. Vet. Sci. | pmid:28231472 |
| Cooper AC et al. | In vitro activity of danofloxacin, tylosin and oxytetracycline against mycoplasmas of veterinary importance. | 1993 | Res. Vet. Sci. | pmid:8393208 |
| Cester CC et al. | Effect of stage of oestrous cycle on tylosin disposition in genital tract secretions of cows. | 1993 | Res. Vet. Sci. | pmid:8434145 |
| El-Ela FI et al. | Investigating the potential role of vitamin E in modulating the immunosuppressive effects of tylvalosin and florfenicol in broiler chickens. | 2016 | Res. Vet. Sci. | pmid:27663366 |
| Hannan PC et al. | Tylosin tartrate and tiamutilin effects on experimental piglet pneumonia induced with pneumonic pig lung homogenate containing mycoplasmas, bacteria and viruses. | 1982 | Res. Vet. Sci. | pmid:7134653 |
| Zweers-Zeilmaker WM et al. | In vitro complex formation and inhibition of hepatic cytochrome P450 activity by different macrolides and tiamulin in goats and cattle. | 1999 | Res. Vet. Sci. | pmid:10088712 |
| Allan EM and Pirie HM | In vitro activity of tiamulin against bovine respiratory tract mycoplasmas. | 1981 | Res. Vet. Sci. | pmid:7323463 |
| Pringle M et al. | Tiamulin resistance in porcine Brachyspira pilosicoli isolates. | 2006 | Res. Vet. Sci. | pmid:16253666 |
| Gourlay RN et al. | Effect of a new macrolide antibiotic (tilmicosin) on pneumonia experimentally induced in calves by Mycoplasma bovis and Pasteurella haemolytica. | 1989 | Res. Vet. Sci. | pmid:2772410 |
| Goodwin RF | In vitro activity of tiamulin against porcine mycoplasmas. | 1985 | Res. Vet. Sci. | pmid:3975477 |
| Prats C et al. | Disposition kinetics of tylosin administered intravenously and intramuscularly to pigs. | 2002 | Res. Vet. Sci. | pmid:12204632 |