Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Digital Dermatitis D058066 3 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Shimada T et al. Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor. 2011 Biotechnol. Bioeng. pmid:20830676
Kim EY et al. Pharmacokinetics of a florfenicol-tylosin combination after intravenous and intramuscular administration to beagle dogs. 2011 J. Vet. Med. Sci. pmid:21068517
Bosi P et al. Feed supplemented with 3 different antibiotics improved food intake and decreased the activation of the humoral immune response in healthy weaned pigs but had differing effects on intestinal microbiota. 2011 J. Anim. Sci. pmid:21724943
Kilpinen S et al. Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial. 2011 Acta Vet. Scand. pmid:21489311
Alexander TW et al. Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. 2011 BMC Microbiol. pmid:21261985
Ozaki H et al. Antimicrobial resistance in fecal Escherichia coli isolated from growing chickens on commercial broiler farms. 2011 Vet. Microbiol. pmid:21232883
Song M et al. The controlled release of tilmicosin from silica nanoparticles. 2011 Drug Dev Ind Pharm pmid:21204738
Stead SL et al. Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21574083
Kucerova Z et al. Antimicrobial susceptibility of Actinobacillus pleuropneumoniae isolates from clinical outbreaks of porcine respiratory diseases. 2011 Vet. Microbiol. pmid:21316872
Guan S et al. Immunosuppressive activity of tilmicosin on the immune responses in mice. 2011 Immunopharmacol Immunotoxicol pmid:20718577
Lombardi KR et al. Pharmacokinetics of tilmicosin in beef cattle following intravenous and subcutaneous administration. 2011 J. Vet. Pharmacol. Ther. pmid:21323676
Xie S et al. Acute toxicity study of tilmicosin-loaded hydrogenated castor oil-solid lipid nanoparticles. 2011 Part Fibre Toxicol pmid:22098626
Danzeisen JL et al. Modulations of the chicken cecal microbiome and metagenome in response to anticoccidial and growth promoter treatment. 2011 PLoS ONE pmid:22114729
Forrester CA et al. Mycoplasma gallisepticum in pheasants and the efficacy of tylvalosin to treat the disease. 2011 Avian Pathol. pmid:22107092
Bohm DA et al. Preparation and characterisation of in-house reference material of tylosin in honey and results of a proficiency test. 2011 Anal. Chim. Acta pmid:21742117
Dinh QT et al. Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. 2011 Talanta pmid:21807177
Gerchman I et al. Characterization of in vivo-acquired resistance to macrolides of Mycoplasma gallisepticum strains isolated from poultry. 2011 Vet. Res. pmid:21810258
Ashenafi D et al. An improved liquid chromatographic method for the analysis of tylosin and its impurities. 2011 J Sep Sci pmid:21812113
Chelliapan S et al. Tolerance of the antibiotic tylosin on treatment performance of an up-flow anaerobic stage reactor (UASR). 2011 Water Sci. Technol. pmid:21866757
Lust EB et al. Human health hazards of veterinary medications: information for emergency departments. 2011 J Emerg Med pmid:20045604