Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Fittipaldi N et al. Assessment of the efficacy of tilmicosin phosphate to eliminate Actinobacillus pleuropneumoniae from carrier pigs. 2005 Can. J. Vet. Res. pmid:15971680
Alippi AM et al. In vitro and in vivo susceptibility of the honeybee bacterial pathogen Paenibacillus larvae subsp. larvae to the antibiotic tylosin. 2005 Vet. Microbiol. pmid:15951140
Wu CM et al. Induction of macrolide resistance in Mycoplasma gallisepticum in vitro and its resistance-related mutations within domain V of 23S rRNA. 2005 FEMS Microbiol. Lett. pmid:15936901
Kolz AC et al. Sorption of tylosin onto swine manure. 2005 Chemosphere pmid:15914248
Vicca J et al. Efficacy of in-feed medication with tylosin for the treatment and control of Mycoplasma hyopneumoniae infections. 2005 Vet. Rec. pmid:15879541
Yong H et al. Design, synthesis and structure-activity relationships of 6-O-arylpropargyl diazalides with potent activity against multidrug-resistant Streptococcus pneumoniae. 2005 Bioorg. Med. Chem. Lett. pmid:15863336
Liutskanova DG et al. [Increase in tylosin production by a commercial strain of Streptomyces fradiae]. 2005 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:15859462
Halling-Sørensen B et al. Dissipation and effects of chlortetracycline and tylosin in two agricultural soils: a field-scale study in southern Denmark. 2005 Environ. Toxicol. Chem. pmid:15839553
Loftin KA et al. Inhibition of microbial metabolism in anaerobic lagoons by selected sulfonamides, tetracyclines, lincomycin, and tylosin tartrate. 2005 Environ. Toxicol. Chem. pmid:15839550
Lu L et al. Autoinducer 2-like activity in poultry-associated enteric bacteria in response to subtherapeutic antibiotic exposure. 2005 Avian Dis. pmid:15839416
Westermarck E et al. Tylosin-responsive chronic diarrhea in dogs. 2005 Mar-Apr J. Vet. Intern. Med. pmid:15822561
Pfister P et al. 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15795375
Blackwell PA et al. Evaluation of a lower tier exposure assessment model for veterinary medicines. 2005 J. Agric. Food Chem. pmid:15769156
Wang J et al. Determination of five macrolide antibiotic residues in eggs using liquid chromatography/electrospray ionization tandem mass spectrometry. 2005 J. Agric. Food Chem. pmid:15769104
Kolz AC et al. Degradation and metabolite production of tylosin in anaerobic and aerobic swine-manure lagoons. 2005 Jan-Feb Water Environ. Res. pmid:15765935
Menozzi A et al. Effect of the macrolide antibacterial drug, tylosin, on TNBS-induced colitis in the rat. 2005 Pharmacology pmid:15756055
Thompson TS et al. Determination of lincomycin and tylosin residues in honey by liquid chromatography/tandem mass spectrometry. 2005 Rapid Commun. Mass Spectrom. pmid:15645470
Rooklidge SJ et al. Modeling antimicrobial contaminant removal in slow sand filtration. 2005 Jan-Feb Water Res. pmid:15644241
Kay P et al. A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data. 2005 Environ. Pollut. pmid:15589660
Stratigopoulos G et al. Positive control of tylosin biosynthesis: pivotal role of TylR. 2004 Mol. Microbiol. pmid:15554972