Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Brain RA et al. Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum. 2005 Environ. Pollut. pmid:15519715
Clark C et al. A preliminary investigation of the disposition of tilmicosin residues in elk tissues and serum. 2004 J. Vet. Pharmacol. Ther. pmid:15500580
Elitok B and Elitok OM Clinical efficacy of carprofen as an adjunct to the antibacterial treatment of bovine respiratory disease. 2004 J. Vet. Pharmacol. Ther. pmid:15500569
Civitareale C et al. Identification and quantification method of spiramycin and tylosin in feedingstuffs with HPLC-UV/DAD at 1 ppm level. 2004 J Pharm Biomed Anal pmid:15496324
Kageyama S et al. Synthesis of 3,4'-dideoxymycaminosyl tylonolide, a novel type of macrolide derivative. 1992 J. Antibiot. pmid:1548187
Novotny GW et al. Ketolide antimicrobial activity persists after disruption of interactions with domain II of 23S rRNA. 2004 Antimicrob. Agents Chemother. pmid:15388419
Brumbaugh GW et al. Susceptibility of Mycobacterium avium sbsp paratuberculosis to monensin sodium or tilmicosin phosphate in vitro and resulting infectivity in a murine model. 2004 Can. J. Vet. Res. pmid:15352541
Poole TL et al. Competitive exclusion of a glycopeptide-resistant Enterococcus faecium in the presence of vancomycin but not equivalent concentrations of tylosin or gentamicin. 2004 Poult. Sci. pmid:15285499
Mathers JJ et al. Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations. 2004 Apr-Jun Avian Dis. pmid:15283418
Lum AM et al. Reverse engineering of industrial pharmaceutical-producing actinomycete strains using DNA microarrays. 2004 Metab. Eng. pmid:15256208
Jackson CR et al. Effects of tylosin use on erythromycin resistance in enterococci isolated from swine. 2004 Appl. Environ. Microbiol. pmid:15240302
Lawrence K Change to user warning for Micotil. 2004 Vet. Rec. pmid:15200081
Kay P et al. Fate of veterinary antibiotics in a macroporous tile drained clay soil. 2004 Environ. Toxicol. Chem. pmid:15180364
Gramse MJ et al. Determination of tylosin in feeds by liquid chromatography with solid-phase extraction. 2004 Mar-Apr J AOAC Int pmid:15164825
Phan LT et al. Synthesis and antibacterial activity of a novel class of 4'-substituted 16-membered ring macrolides derived from tylosin. 2004 J. Med. Chem. pmid:15163176
Rowan TG et al. Efficacy of danofloxacin in the treatment of respiratory disease in European cattle. 2004 Vet. Rec. pmid:15160844
Pettis JS et al. Larval Apis mellifera L. (Hymenoptera: Apidae) mortality after topical application of antibiotics and dusts. 2004 J. Econ. Entomol. pmid:15154433
Fajt VR et al. Effect of danofloxacin and tilmicosin on body temperatures of beef calves with pneumonia experimentally induced by inoculation with Mannheimia haemolytica. 2004 Am. J. Vet. Res. pmid:15141881
Van Poucke C et al. Tylosin detection in animal feed by liquid chromatography-tandem mass spectrometry with enzymatic hydrolysis of the tylosin urea adduct. 2004 J. Agric. Food Chem. pmid:15137817
Zhang Y et al. Residue depletion of tilmicosin in chicken tissues. 2004 J. Agric. Food Chem. pmid:15113165