Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Pfister P et al. 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15795375
Thompson TS et al. Determination of lincomycin and tylosin residues in honey by liquid chromatography/tandem mass spectrometry. 2005 Rapid Commun. Mass Spectrom. pmid:15645470
Kiehl DE and Kennington AS Analysis of tilmicosin in swine liver extracts by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. 1995 Rapid Commun. Mass Spectrom. pmid:8527821
Stoev G and Nazarov V Identification of the related substances of tilmicosin by liquid chromatography/ion trap mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18491285
Song W et al. Determination of amprolium, carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry. 2007 Rapid Commun. Mass Spectrom. pmid:17510929
Hao H et al. Microbiological toxicity of tilmicosin on human colonic microflora in chemostats. 2015 Regul. Toxicol. Pharmacol. pmid:26190303
Akhter S et al. Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. 2008 Reprod. Domest. Anim. pmid:18042206
Yildiz S et al. Tylosin does not affect GnRH-induced LH secretion in rams. 2004 Jan-Feb Reprod. Toxicol. pmid:15013072
Zweers-Zeilmaker WM et al. In vitro complex formation and inhibition of hepatic cytochrome P450 activity by different macrolides and tiamulin in goats and cattle. 1999 Res. Vet. Sci. pmid:10088712
Allan EM and Pirie HM In vitro activity of tiamulin against bovine respiratory tract mycoplasmas. 1981 Res. Vet. Sci. pmid:7323463