Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kim HB et al. | Microbial shifts in the swine distal gut in response to the treatment with antimicrobial growth promoter, tylosin. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22955886 |
Malaiyandi V et al. | Airborne allergic contact dermatitis from tylosin in pharmacy compounders and cross-sensitization to macrolide antibiotics. | 2012 Sep-Oct | Dermatitis | pmid:23010831 |
Gaudin V et al. | Validation of two ELISA kits for the screening of tylosin and streptomycin in honey according to the European decision 2002/657/EC. | 2013 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:23013044 |
Devreese M et al. | An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents. | 2013 | Toxicol In Vitro | pmid:23078954 |
Del Pozo Sacristán R et al. | Efficacy of in-feed medication with chlortetracycline in a farrow-to-finish herd against a clinical outbreak of respiratory disease in fattening pigs. | 2012 Dec 22-29 | Vet. Rec. | pmid:23136309 |
Westermarck E and Wiberg M | Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. | 2012 | Top Companion Anim Med | pmid:23148848 |
Er A and Yazar E | Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury. | 2012 | Acta Vet. Hung. | pmid:23160029 |
Tsutsui A et al. | Antimalarial C-9 oxime derivatives from desmycosin, produced by click chemistry. | 2013 | J. Antibiot. | pmid:23232930 |
Burkin MA and Galvidis IA | Hapten modification approach for switching immunoassay specificity from selective to generic. | 2013 | J. Immunol. Methods | pmid:23234756 |
Fujiwara T et al. | Absorption, tissue distribution and excretion of 19-deformyldesmycosin derivatives, new 16-membered macrolides, in mice. | 1990 | J. Antibiot. | pmid:2324015 |
Hao H et al. | Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. | 2013 | Antimicrob. Agents Chemother. | pmid:23274667 |
Whitehead TR and Cotta MA | Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. | 2013 | Lett. Appl. Microbiol. | pmid:23297734 |
MiliavskiÄ EB et al. | [Electrophoretic separation of spores of producers of kanamycin and tylosin]. | 1990 | Antibiot. Khimioter. | pmid:2334246 |
Ali M et al. | Effect of redox potential and pH status on degradation and adsorption behavior of tylosin in dairy lagoon sediment suspension. | 2013 | Chemosphere | pmid:23352520 |
Holman DB and Chénier MR | Impact of subtherapeutic administration of tylosin and chlortetracycline on antimicrobial resistance in farrow-to-finish swine. | 2013 | FEMS Microbiol. Ecol. | pmid:23397987 |
Pinckney JL et al. | Sublethal effects of the antibiotic tylosin on estuarine benthic microalgal communities. | 2013 | Mar. Pollut. Bull. | pmid:23398744 |
Meyer NF et al. | Effects of monensin and tylosin in finishing diets containing corn wet distillers grains with solubles with differing corn processing methods. | 2013 | J. Anim. Sci. | pmid:23422007 |
Lin J et al. | Response of intestinal microbiota to antibiotic growth promoters in chickens. | 2013 | Foodborne Pathog. Dis. | pmid:23461609 |
Garcés-Narro C et al. | Efficacy of low-dose tylvalosin for the control of clostridiosis in broilers and its effect on productive parameters. | 2013 | Poult. Sci. | pmid:23472021 |
Pan R et al. | Extraction of trace tilmicosin in real water samples using ionic liquid-based aqueous two-phase systems. | 2013 | Water Sci. Technol. | pmid:23579819 |
Chopra S et al. | Characterization of impurities in tylosin using dual liquid chromatography combined with ion trap mass spectrometry. | 2013 | Talanta | pmid:23598092 |
Amachawadi RG et al. | Occurrence of the transferable copper resistance gene tcrB among fecal enterococci of U.S. feedlot cattle fed copper-supplemented diets. | 2013 | Appl. Environ. Microbiol. | pmid:23666328 |
Topp E et al. | Accelerated Biodegradation of Veterinary Antibiotics in Agricultural Soil following Long-Term Exposure, and Isolation of a Sulfamethazine-degrading sp. | J. Environ. Qual. | pmid:23673752 | |
Fujiwara T and Takenaka S | Bioconversion of 19-deformyl-5-O-desosaminyl tylonolide to 19-deformyl-4'-deoxydesmycosin (TMC-016). | 1990 | FEMS Microbiol. Lett. | pmid:2379808 |
Mitchell JD et al. | In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. | 2013 | Vet. J. | pmid:23810743 |
Panfilova ZI et al. | [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. | 1990 | Antibiot. Khimioter. | pmid:2383150 |
Buß M et al. | Quality control ranges for tylosin 30 μg and 15 μg discs applicable to Staphylococcus aureus ATCC(R) 25923. | 2014 | J. Antimicrob. Chemother. | pmid:23928021 |
Svartström O et al. | Characterization of Treponema spp. isolates from pigs with ear necrosis and shoulder ulcers. | 2013 | Vet. Microbiol. | pmid:23948134 |
GarcÃa-Sánchez L et al. | Occurrence of tylosin in swine wastewater in Mexico. | 2013 | Water Sci. Technol. | pmid:23985521 |
Zhang Q et al. | Sorption of tylosin on clay minerals. | 2013 | Chemosphere | pmid:24007614 |
Herd MB et al. | Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. | 2013 | J. Neurosci. | pmid:24027285 |
Corns SM et al. | Development of antibiotic regimens using graph based evolutionary algorithms. | 2013 | BioSystems | pmid:24051263 |
Kolanović BS et al. | Tylosin content in meat and honey samples over a two-year period in Croatia. | 2014 | J Immunoassay Immunochem | pmid:24063615 |
Stackhouse-Lawson KR et al. | Growth promoting technologies reduce greenhouse gas, alcohol, and ammonia emissions from feedlot cattle. | 2013 | J. Anim. Sci. | pmid:24085413 |
Shishkina A et al. | Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel. | 2013 | Bioconjug. Chem. | pmid:24090034 |
Mitchell SM et al. | The effects of the antibiotics ampicillin, florfenicol, sulfamethazine, and tylosin on biogas production and their degradation efficiency during anaerobic digestion. | 2013 | Bioresour. Technol. | pmid:24113548 |
Pilcher CM et al. | Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. | 2013 | J. Anim. Sci. | pmid:24126274 |
Guo X et al. | The influences of pH and ionic strength on the sorption of tylosin on goethite. | 2014 | Environ Sci Pollut Res Int | pmid:24197966 |
Pei Z et al. | Effects of copper and aluminum on the adsorption of sulfathiazole and tylosin on peat and soil. | 2014 | Environ. Pollut. | pmid:24201036 |
Amrine DE et al. | Pulmonary lesions and clinical disease response to Mannheimia haemolytica challenge 10 days following administration of tildipirosin or tulathromycin. | 2014 | J. Anim. Sci. | pmid:24243906 |
Kawai K et al. | Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan. | 2014 | Anim. Sci. J. | pmid:24261609 |
Khaliq S et al. | Characterization of mutations in regulatory genes of Tyl cluster leading to overexpression of tylosin in mutant γ-1 of Streptomyces fradiae NRRL-2702. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24270892 |
Ji LW et al. | Comparative pharmacokinetics and bioavailability of tylosin tartrate and tylosin phosphate after a single oral and i.v. administration in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24325541 |
Srinivasan P et al. | Sorption of selected veterinary antibiotics onto dairy farming soils of contrasting nature. | 2014 | Sci. Total Environ. | pmid:24326064 |
Lerner U et al. | Acquired resistance to the 16-membered macrolides tylosin and tilmicosin by Mycoplasma bovis. | 2014 | Vet. Microbiol. | pmid:24393633 |
Entorf M et al. | Tylosin susceptibility of Staphylococci from bovine mastitis. | 2014 | Vet. Microbiol. | pmid:24461550 |
Marosevic D et al. | In vivo spread of macrolide-lincosamide-streptogramin B (MLSB) resistance--a model study in chickens. | 2014 | Vet. Microbiol. | pmid:24467930 |
Beck P et al. | Additive effects of growth promoting technologies on performance of grazing steers and economics of the wheat pasture enterprise. | 2014 | J. Anim. Sci. | pmid:24492552 |
Ferrag-Siagh F et al. | Electro-Fenton pretreatment for the improvement of tylosin biodegradability. | 2014 | Environ Sci Pollut Res Int | pmid:24705893 |
Kim HB et al. | Effects of tylosin administration on C-reactive protein concentration and carriage of Salmonella enterica in pigs. | 2014 | Am. J. Vet. Res. | pmid:24762018 |