Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nguyen LT et al. | The tylosin producer, Streptomyces fradiae, contains a second valine dehydrogenase. | 1995 | Microbiology (Reading, Engl.) | pmid:7773408 |
Shryock TR et al. | Proposed quality control guidelines for antimicrobial susceptibility tests using tilmicosin. | 1995 | J. Clin. Microbiol. | pmid:7714188 |
Bobillot S et al. | Chemical modification of tylosin. | 1995 | J. Antibiot. | pmid:7649866 |
Creemer LC et al. | Synthesis, antimicrobial activity and in vivo fluorine NMR of a hexafluorinated derivative of tilmicosin. | 1995 | J. Antibiot. | pmid:7649867 |
Narandja A et al. | 10,11,12,13-Tetrahydro derivatives of tylosin. II. Synthesis, antibacterial activity and tissue of 4'-deoxy-10,11,12,13-tetrahydrodesmycosin. | 1995 | J. Antibiot. | pmid:7730160 |
Paesen J et al. | Study of the stability of tylosin A in aqueous solutions. | 1995 | J Pharm Biomed Anal | pmid:8573642 |
Ziv G et al. | Disposition kinetics of tylosin tartrate administered intravenously and intramuscularly to normal and water-deprived camels. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8583543 |
Ziv G et al. | Tilmicosin antibacterial activity and pharmacokinetics in cows. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587151 |
Brown SA et al. | Characterization of plasma and lung concentrations after ceftiofur sodium and tilmicosin phosphate administered subcutaneously to mice. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8587160 |
Blackall PJ et al. | In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Actinobacillus pleuropneumoniae from pigs. | 1995 | Aust. Vet. J. | pmid:8787526 |
Tuomi ML and Räsänen L | Contact allergy to tylosin and cobalt in a pig-farmer. | 1995 | Contact Derm. | pmid:8654098 |
Zuzulova M et al. | In vitro activity of tylosin and its derivatives against Ureaplasma urealyticum. | 1995 | Arzneimittelforschung | pmid:8929244 |
Galyean ML et al. | Effects of arrival medication with tilmicosin phosphate on health and performance of newly received beef cattle. | 1995 | J. Anim. Sci. | pmid:7665351 |
Scott PR | Efficacy of strategic tilmicosin injection during an outbreak of respiratory disease in housed beef calves. | 1995 Sep-Oct | Br. Vet. J. | pmid:8556318 |
Katoh T et al. | Effect of a combination of antimicrobial agents for the treatment of respiratory disease in cattle. | 1996 | J. Vet. Med. Sci. | pmid:8877980 |
McKay SG et al. | Use of tilmicosin for treatment of pasteurellosis in rabbits. | 1996 | Am. J. Vet. Res. | pmid:8836371 |
Shryock TR et al. | Minimum inhibitory concentration breakpoints and disk diffusion inhibitory zone interpretive criteria for tilmicosin susceptibility testing against Pasteurella spp. associated with bovine respiratory disease. | 1996 | J. Vet. Diagn. Invest. | pmid:8844577 |
Scott DW et al. | Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1996 | Can. Vet. J. | pmid:8896878 |
Harvey RG | Tylosin in the treatment of canine superficial pyoderma. | 1996 | Vet. Rec. | pmid:8873399 |
Kobayashi H et al. | In vitro susceptibility of Mycoplasma hyosynoviae and M. hyorhinis to antimicrobial agents. | 1996 | J. Vet. Med. Sci. | pmid:8959659 |