Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Taniguchi K et al. | The role of histidine residues conserved in the putative ATP-binding region of macrolide 2'-phosphotransferase II. | 2004 | FEMS Microbiol. Lett. | pmid:15033229 |
Fouces R et al. | Conjugation and transformation of Streptomyces species by tylosin resistance. | 2000 | FEMS Microbiol. Lett. | pmid:10802191 |
Wu CM et al. | Induction of macrolide resistance in Mycoplasma gallisepticum in vitro and its resistance-related mutations within domain V of 23S rRNA. | 2005 | FEMS Microbiol. Lett. | pmid:15936901 |
Fujiwara T and Takenaka S | Bioconversion of 19-deformyl-5-O-desosaminyl tylonolide to 19-deformyl-4'-deoxydesmycosin (TMC-016). | 1990 | FEMS Microbiol. Lett. | pmid:2379808 |
Higgins HC and McEvoy JD | Accelerated solvent extraction of animal feedingstuffs for microbial growth inhibition screening for the presence of antimicrobial feed additives. | 2002 | Food Addit Contam | pmid:12396393 |
Montesissa C et al. | Tylosin depletion in edible tissues of turkeys. | 1999 | Food Addit Contam | pmid:10755131 |
Koenen-Dierick K and De Beer JO | Optimization of an antibiotic residue screening test, based on inhibition of Bacillus subtilis BGA, with experimental design. | 1998 | Food Addit Contam | pmid:9829036 |
Vincent U et al. | Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. | 2007 | Food Addit Contam | pmid:17454108 |
Patyra E et al. | Development and validation of an LC-MS/MS method for the quantification of tiamulin, trimethoprim, tylosin, sulfadiazine and sulfamethazine in medicated feed. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:29324179 |
Cornejo J et al. | Depletion of tylosin residues in feathers, muscle and liver from broiler chickens after completion of antimicrobial therapy. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:29111882 |
De Baere S et al. | In vitro model to assess the adsorption of oral veterinary drugs to mycotoxin binders in a feed- and aflatoxin B1-containing buffered matrix. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:30016205 |
Le T et al. | A quantum dot-based immunoassay for screening of tylosin and tilmicosin in edible animal tissues. | 2015 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:25822697 |
Stead SL et al. | Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. | 2011 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:21574083 |
Gaudin V et al. | Validation of two ELISA kits for the screening of tylosin and streptomycin in honey according to the European decision 2002/657/EC. | 2013 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:23013044 |
Pol-Hofstad I et al. | Collaborative study of a microbiological screening method (three-plate) for the banned antimicrobial growth promotors tylosin, virginiamycin, spiramycin, zinc bacitracin and avoparcin in animal feed. | 2008 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680856 |
Baggio A et al. | Residues of antibacterial drugs in honey from the Italian market. | 2009 | Food Addit Contam Part B Surveill | pmid:24784967 |
Molognoni L et al. | Development of a LC-MS/MS method for the simultaneous determination of sorbic acid, natamycin and tylosin in Dulce de leche. | 2016 | Food Chem | pmid:27283692 |
Amachawadi RG et al. | Effects of In-Feed Copper, Chlortetracycline, and Tylosin on the Prevalence of Transferable Copper Resistance Gene, tcrB, Among Fecal Enterococci of Weaned Piglets. | 2015 | Foodborne Pathog. Dis. | pmid:26258261 |
Apley MD et al. | Use estimates of in-feed antimicrobials in swine production in the United States. | 2012 | Foodborne Pathog. Dis. | pmid:22324295 |
Lin J et al. | Response of intestinal microbiota to antibiotic growth promoters in chickens. | 2013 | Foodborne Pathog. Dis. | pmid:23461609 |