Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Mathers JJ et al. | Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations. | 2004 Apr-Jun | Avian Dis. | pmid:15283418 |
Poole TL et al. | Competitive exclusion of a glycopeptide-resistant Enterococcus faecium in the presence of vancomycin but not equivalent concentrations of tylosin or gentamicin. | 2004 | Poult. Sci. | pmid:15285499 |
Brumbaugh GW et al. | Susceptibility of Mycobacterium avium sbsp paratuberculosis to monensin sodium or tilmicosin phosphate in vitro and resulting infectivity in a murine model. | 2004 | Can. J. Vet. Res. | pmid:15352541 |
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Clark C et al. | A preliminary investigation of the disposition of tilmicosin residues in elk tissues and serum. | 2004 | J. Vet. Pharmacol. Ther. | pmid:15500580 |
Brain RA et al. | Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum. | 2005 | Environ. Pollut. | pmid:15519715 |
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Wu CM et al. | Induction of macrolide resistance in Mycoplasma gallisepticum in vitro and its resistance-related mutations within domain V of 23S rRNA. | 2005 | FEMS Microbiol. Lett. | pmid:15936901 |
Alippi AM et al. | In vitro and in vivo susceptibility of the honeybee bacterial pathogen Paenibacillus larvae subsp. larvae to the antibiotic tylosin. | 2005 | Vet. Microbiol. | pmid:15951140 |
Fittipaldi N et al. | Assessment of the efficacy of tilmicosin phosphate to eliminate Actinobacillus pleuropneumoniae from carrier pigs. | 2005 | Can. J. Vet. Res. | pmid:15971680 |
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Rooney KA et al. | Efficacy of tulathromycin compared with tilmicosin and florfenicol for the control of respiratory disease in cattle at high risk of developing bovine respiratory disease. | 2005 | Vet. Ther. | pmid:16094563 |
Nutsch RG et al. | Comparative efficacy of tulathromycin, tilmicosin, and florfenicol in the treatment of bovine respiratory disease in stocker cattle. | 2005 | Vet. Ther. | pmid:16094564 |
Skogerboe TL et al. | Comparative efficacy of tulathromycin versus florfenicol and tilmicosin against undifferentiated bovine respiratory disease in feedlot cattle. | 2005 | Vet. Ther. | pmid:16094565 |
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Chun S et al. | Effect of agricultural antibiotics on the persistence and transformation of 17beta-estradiol in a Sequatchie loam. | 2005 | J Environ Sci Health B | pmid:16190018 |
Clay SA et al. | Tylosin sorption to silty clay loam soils, swine manure, and sand. | 2005 | J Environ Sci Health B | pmid:16194921 |
Brumbaugh GW et al. | Effect of tilmicosin on chemotactic, phagocytic, and bactericidal activities of bovine and porcine alveolar macrophages. | 2002 | Am. J. Vet. Res. | pmid:16206777 |
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Ayling RD et al. | Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. | 2005 | Antimicrob. Agents Chemother. | pmid:16304194 |
Beier RC et al. | Production and characterization of monoclonal antibodies against the antibiotic tilmicosin. | 2005 | J. Agric. Food Chem. | pmid:16332115 |
Fu H et al. | Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16343900 |
Westermarck E et al. | Effect of diet and tylosin on chronic diarrhea in beagles. | 2005 Nov-Dec | J. Vet. Intern. Med. | pmid:16355675 |
Chelliapan S et al. | Performance of an up-flow anaerobic stage reactor (UASR) in the treatment of pharmaceutical wastewater containing macrolide antibiotics. | 2006 | Water Res. | pmid:16387347 |
Jacobsen AM and Halling-Sørensen B | Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. | 2006 | Anal Bioanal Chem | pmid:16485090 |
Jung WS et al. | Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16493552 |
Carlson JC and Mabury SA | Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. | 2006 | Environ. Toxicol. Chem. | pmid:16494218 |
Nozal Nalda MJ et al. | Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. | 2006 | J Sep Sci | pmid:16544883 |
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Dingwell RT et al. | Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. | 2006 | Can. J. Vet. Res. | pmid:16639943 |
Cao XY et al. | Tilmicosin and tylosin have anti-inflammatory properties via modulation of COX-2 and iNOS gene expression and production of cytokines in LPS-induced macrophages and monocytes. | 2006 | Int. J. Antimicrob. Agents | pmid:16647840 |
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McAllister TA et al. | Shedding of escherichia coli O157:H7 by cattle fed diets containing monensin or tylosin. | 2006 | J. Food Prot. | pmid:16995508 |
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Bignell DR et al. | Regulation of tylosin production: role of a TylP-interactive ligand. | 2007 | Mol. Microbiol. | pmid:17181783 |
Blackwell PA et al. | The dissipation and transport of veterinary antibiotics in a sandy loam soil. | 2007 | Chemosphere | pmid:17204303 |
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Abu-Basha EA et al. | Pharmacokinetics of tilmicosin (Provitil powder and Pulmotil liquid AC) oral formulations in chickens. | 2007 | Vet. Res. Commun. | pmid:17225089 |
McDougall S et al. | Parenteral treatment of clinical mastitis with tylosin base or penethamate hydriodide in dairy cattle. | 2007 | J. Dairy Sci. | pmid:17235155 |
González de la Huebra MJ et al. | Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD). | 2007 | J Pharm Biomed Anal | pmid:17257795 |
Lin J et al. | Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens. | 2007 | Antimicrob. Agents Chemother. | pmid:17353243 |
Litterio NJ et al. | Microbiological screening test validation for detection of tylosin excretion in milk of cows with low and high somatic cell counts. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17359452 |
Kart A et al. | The possible protective effect of L-carnitine on tilmicosin-induced cardiotoxicity in mice. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17381679 |
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