Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Tracheal Diseases D014133 3 associated lipids
Treponemal Infections D014211 3 associated lipids
Digital Dermatitis D058066 3 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Dysentery D004403 4 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Foreign Bodies D005547 5 associated lipids
Clostridium Infections D003015 5 associated lipids
Pyoderma D011711 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Arisawa A et al. Cloning of the macrolide antibiotic biosynthesis gene acyA, which encodes 3-O-acyltransferase, from Streptomyces thermotolerans and its use for direct fermentative production of a hybrid macrolide antibiotic. 1994 Appl. Environ. Microbiol. pmid:8074537
Lee SH and Lee KJ Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae. 1993 Appl. Environ. Microbiol. pmid:8481008
Amachawadi RG et al. Occurrence of the transferable copper resistance gene tcrB among fecal enterococci of U.S. feedlot cattle fed copper-supplemented diets. 2013 Appl. Environ. Microbiol. pmid:23666328
Wagner BA et al. Effect of antimicrobial dosage regimen on Salmonella and Escherichia coli isolates from feeder swine. 2008 Appl. Environ. Microbiol. pmid:18223115
DENNY CB et al. Effects of tylosin and nisin on canned food spoilage bacteria. 1961 Appl Microbiol pmid:13721908
Whitehead TR et al. Savagea faecisuis gen. nov., sp. nov., a tylosin- and tetracycline-resistant bacterium isolated from a swine-manure storage pit. 2015 Antonie Van Leeuwenhoek pmid:25980832
Baltz RH et al. Applications of transposition mutagenesis in antibiotic producing streptomycetes. 1997 Antonie Van Leeuwenhoek pmid:9049029
Cundliffe E et al. The tylosin-biosynthetic genes of Streptomyces fradiae. 2001 Antonie Van Leeuwenhoek pmid:11816964
Elkins CA and Mullis LB Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. 2007 Antimicrob. Agents Chemother. pmid:17210767
Memili E and Weisblum B Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae. 1997 Antimicrob. Agents Chemother. pmid:9145902