Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Conjunctivitis, Viral D003236 1 associated lipids
Enterotoxemia D004767 1 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Tracheal Diseases D014133 3 associated lipids
Treponemal Infections D014211 3 associated lipids
Digital Dermatitis D058066 3 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Dysentery D004403 4 associated lipids
Mycotoxicosis D015651 5 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Foreign Bodies D005547 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Prats C et al. Tylosin depletion from edible pig tissues. 2002 Res. Vet. Sci. pmid:12443694
El-Ela FI et al. Investigating the potential role of vitamin E in modulating the immunosuppressive effects of tylvalosin and florfenicol in broiler chickens. 2016 Res. Vet. Sci. pmid:27663366
Pringle M et al. Tiamulin resistance in porcine Brachyspira pilosicoli isolates. 2006 Res. Vet. Sci. pmid:16253666
Yildiz S et al. Tylosin does not affect GnRH-induced LH secretion in rams. 2004 Jan-Feb Reprod. Toxicol. pmid:15013072
Akhter S et al. Effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (Bubalus bubalis) bull semen. 2008 Reprod. Domest. Anim. pmid:18042206
Hao H et al. Microbiological toxicity of tilmicosin on human colonic microflora in chemostats. 2015 Regul. Toxicol. Pharmacol. pmid:26190303
Thompson TS et al. Determination of lincomycin and tylosin residues in honey by liquid chromatography/tandem mass spectrometry. 2005 Rapid Commun. Mass Spectrom. pmid:15645470
Kiehl DE and Kennington AS Analysis of tilmicosin in swine liver extracts by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. 1995 Rapid Commun. Mass Spectrom. pmid:8527821
Stoev G and Nazarov V Identification of the related substances of tilmicosin by liquid chromatography/ion trap mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18491285
Song W et al. Determination of amprolium, carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry. 2007 Rapid Commun. Mass Spectrom. pmid:17510929
Liu M and Douthwaite S Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12417742
Pfister P et al. 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15795375
Kim HB et al. Microbial shifts in the swine distal gut in response to the treatment with antimicrobial growth promoter, tylosin. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22955886
Fishman SE et al. Cloning genes for the biosynthesis of a macrolide antibiotic. 1987 Proc. Natl. Acad. Sci. U.S.A. pmid:3479787
Baltadzhieva D et al. [Tylosin-specific proliferation in vitro of the peripheral blood mononuclear cells in occupational tylosin allergy]. 1997 Probl Khig pmid:10202771
Liutskanova DG et al. [Increase in tylosin production by a commercial strain of Streptomyces fradiae]. 2005 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:15859462
Weber NR et al. Batch medication of intestinal infections in nursery pigs-A randomised clinical trial on the efficacy of treatment strategy, type of antibiotic and bacterial load on average daily weight gain. 2017 Prev. Vet. Med. pmid:28107883
Rérat M et al. Bovine respiratory disease: efficacy of different prophylactic treatments in veal calves and antimicrobial resistance of isolated Pasteurellaceae. 2012 Prev. Vet. Med. pmid:21945813
Persoons D et al. Antimicrobial use in Belgian broiler production. 2012 Prev. Vet. Med. pmid:22459488
Dafwang II et al. Broiler chick growth response to antibiotics, 1981-1982. 1984 Poult. Sci. pmid:6610176