| MeSH term | MeSH ID | Detail |
|---|---|---|
| Asthma | D001249 | 52 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Campylobacter Infections | D002169 | 13 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Conjunctivitis, Viral | D003236 | 1 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Dysentery | D004403 | 4 associated lipids |
| Enterotoxemia | D004767 | 1 associated lipids |
| Erysipelothrix Infections | D004889 | 1 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Keratoconjunctivitis, Infectious | D007639 | 2 associated lipids |
| Liver Abscess | D008100 | 6 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Samii SS et al. | Effects of limonene on ruminal concentrations, fermentation, and lysine degradation in cattle. | 2016 | J. Anim. Sci. | pmid:27695807 |
| Tereshchenkov AG et al. | New Fluorescent Macrolide Derivatives for Studying Interactions of Antibiotics and Their Analogs with the Ribosomal Exit Tunnel. | 2016 | Biochemistry Mosc. | pmid:27908240 |
| Li Y et al. | In vitro susceptibility of four antimicrobials against Riemerella anatipestifer isolates: a comparison of minimum inhibitory concentrations and mutant prevention concentrations for ceftiofur, cefquinome, florfenicol, and tilmicosin. | 2016 | BMC Vet. Res. | pmid:27829415 |
| Angell JW et al. | Whole-flock, metaphylactic tilmicosin failed to eliminate contagious ovine digital dermatitis and footrot in sheep: a cluster randomised trial. | 2016 | Vet. Rec. | pmid:27450091 |
| Galmozzi CV et al. | The Cyanobacterial Ribosomal-Associated Protein LrtA Is Involved in Post-Stress Survival in Synechocystis sp. PCC 6803. | 2016 | PLoS ONE | pmid:27442126 |
| Cernicchiaro N et al. | Meta-analysis of the effects of laidlomycin propionate, fed alone or in combination with chlortetracycline, compared with monensin sodium, fed alone or in combination with tylosin, on growth performance, health, and carcass outcomes in finishing steers in North America. | 2016 | J. Anim. Sci. | pmid:27136025 |
| Kim J et al. | Effects of the Antibiotics Growth Promoter Tylosin on Swine Gut Microbiota. | 2016 | J. Microbiol. Biotechnol. | pmid:26869601 |
| Cleary DW et al. | Long-term antibiotic exposure in soil is associated with changes in microbial community structure and prevalence of class 1 integrons. | 2016 | FEMS Microbiol. Ecol. | pmid:27495240 |
| Molognoni L et al. | Development of a LC-MS/MS method for the simultaneous determination of sorbic acid, natamycin and tylosin in Dulce de leche. | 2016 | Food Chem | pmid:27283692 |
| Kim E et al. | Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in Tylosin. | 2016 | J. Nat. Prod. | pmid:27453999 |
| Kline A and Pinckney JL | Size-selective toxicity effects of the antimicrobial tylosin on estuarine phytoplankton communities. | 2016 | Environ. Pollut. | pmid:27376985 |
| Besserer F et al. | Tilmicosin toxicity: a case of accidental human tilmicosin injection managed with calcium, high-dose insulin and intravenous lipid emulsion therapy. | 2016 | Clin Toxicol (Phila) | pmid:27207720 |
| Guo X et al. | Sorption of tylosin and sulfamethazine on solid humic acid. | 2016 | J Environ Sci (China) | pmid:27155426 |
| Crepieux T et al. | Randomized, non-inferiority trial comparing a nitric oxide releasing solution with a macrolide antibiotic for control of bovine respiratory disease in beef feedlot calves at high-risk of developing respiratory tract disease. | 2016 | Res. Vet. Sci. | pmid:27033936 |
| Confer AW et al. | Clinical disease and lung lesions in calves experimentally inoculated with Histophilus somni five days after metaphylactic administration of tildipirosin or tulathromycin. | 2016 | Am. J. Vet. Res. | pmid:27027834 |
| Torres F et al. | Pharmacokinetics of tildipirosin in pig tonsils. | 2016 | J. Vet. Pharmacol. Ther. | pmid:26935349 |
| Luby EM et al. | Fate and transport of tylosin-resistant bacteria and macrolide resistance genes in artificially drained agricultural fields receiving swine manure. | 2016 | Sci. Total Environ. | pmid:26874610 |
| Rose M et al. | A microbiological assay to estimate the antimicrobial activity of parenteral tildipirosin against foodborne pathogens and commensals in the colon of beef cattle and pigs. | 2016 | J. Vet. Pharmacol. Ther. | pmid:26538405 |
| El-Mahmoudy A and Gheith I | The anti-nociceptive potential of tilmicosin against chemical-induced but not thermal-induced pain in mice. | 2016 | Int J Immunopathol Pharmacol | pmid:26519523 |
| Krokidis M et al. | The slow dissociation rate of K-1602 contributes to the enhanced inhibitory activity of this novel alkyl-aryl-bearing fluoroketolide. | 2016 | J Enzyme Inhib Med Chem | pmid:25807301 |
| Amarakoon ID et al. | Dissipation of Antimicrobials in a Seasonally Frozen Soil after Beef Cattle Manure Application. | 2016 | J. Environ. Qual. | pmid:27695746 |
| Whitehead TR and Cotta MA | Examination of the Aerobic Microflora of Swine Feces and Stored Swine Manure. | 2016 | J. Environ. Qual. | pmid:27065407 |
| Amarakoon ID et al. | Dissipation of Antimicrobials in Feedlot Manure Compost after Oral Administration versus Fortification after Excretion. | 2016 | J. Environ. Qual. | pmid:27065397 |
| Entorf M et al. | Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. | 2016 | Vet. Microbiol. | pmid:26732695 |
| Makarov GI et al. | Structural Insight into Interaction between C20 Phenylalanyl Derivative of Tylosin and Ribosomal Tunnel. | 2017 | Biochemistry Mosc. | pmid:28941460 |
| Berman J et al. | A randomised clinical trial of a metaphylactic treatment with tildipirosin for bovine respiratory disease in veal calves. | 2017 | BMC Vet. Res. | pmid:28615070 |
| Li B et al. | EFFICACY AND SAFETY OF BAN HUANG ORAL LIQUID FOR TREATING BOVINE RESPIRATORY DISEASES. | 2017 | Afr J Tradit Complement Altern Med | pmid:28573221 |
| Krongdang S et al. | Multilocus sequence typing, biochemical and antibiotic resistance characterizations reveal diversity of North American strains of the honey bee pathogen Paenibacillus larvae. | 2017 | PLoS ONE | pmid:28467471 |
| Kreizinger Z et al. | Antibiotic susceptibility profiles of Mycoplasma synoviae strains originating from Central and Eastern Europe. | 2017 | BMC Vet. Res. | pmid:29149886 |
| Qekwana DN et al. | Patterns and predictors of antimicrobial resistance among Staphylococcus spp. from canine clinical cases presented at a veterinary academic hospital in South Africa. | 2017 | BMC Vet. Res. | pmid:28454567 |
| Weber NR et al. | Batch medication of intestinal infections in nursery pigs-A randomised clinical trial on the efficacy of treatment strategy, type of antibiotic and bacterial load on average daily weight gain. | 2017 | Prev. Vet. Med. | pmid:28107883 |
| Zhang N et al. | Determination of the Mutant Selection Window and Evaluation of the Killing of Mycoplasma gallisepticum by Danofloxacin, Doxycycline, Tilmicosin, Tylvalosin and Valnemulin. | 2017 | PLoS ONE | pmid:28052123 |
| Timsit E et al. | Effects of nasal instillation of a nitric oxide-releasing solution or parenteral administration of tilmicosin on the nasopharyngeal microbiota of beef feedlot cattle at high-risk of developing respiratory tract disease. | 2017 | Res. Vet. Sci. | pmid:28231472 |
| De Mil T et al. | Influence of mycotoxin binders on the oral bioavailability of tylosin, doxycycline, diclazuril, and salinomycin in fed broiler chickens. | 2017 | Poult. Sci. | pmid:28160001 |
| Sato T et al. | Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. | 2017 | Microbiol. Immunol. | pmid:28504455 |
| Weinroth MD et al. | Rapid Communication: 16S ribosomal ribonucleic acid characterization of liver abscesses in feedlot cattle from three states in the United States. | 2017 | J. Anim. Sci. | pmid:29108068 |
| Zhang YJ et al. | Temporal succession of soil antibiotic resistance genes following application of swine, cattle and poultry manures spiked with or without antibiotics. | 2017 | Environ. Pollut. | pmid:28964602 |
| Ruiz VE et al. | A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity. | 2017 | Nat Commun | pmid:28894149 |
| Hossain A et al. | Occurrence, distribution, ecological and resistance risks of antibiotics in surface water of finfish and shellfish aquaculture in Bangladesh. | 2017 | Chemosphere | pmid:28888121 |
| Amachawadi RG et al. | Bacterial flora of liver abscesses in crossbred beef cattle and Holstein steers fed finishing diets with or without tylosin. | 2017 | J. Anim. Sci. | pmid:28805921 |
| Sugawara A et al. | 5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity. | 2017 | J. Antibiot. | pmid:28559578 |
| Teixeira AGV et al. | Efficacy of tildipirosin metaphylaxis for the prevention of respiratory disease, otitis and mortality in pre-weaned Holstein calves. | 2017 | Vet. J. | pmid:28093111 |
| Cheng J et al. | Microstructure and antioxidative capacity of the microalgae mutant Chlorella PY-ZU1 during tilmicosin removal from wastewater under 15% CO. | 2017 | J. Hazard. Mater. | pmid:27829514 |
| Ling Z et al. | Preparation, characterization, and pharmacokinetics of tilmicosin- and florfenicol-loaded hydrogenated castor oil-solid lipid nanoparticles. | 2017 | J. Vet. Pharmacol. Ther. | pmid:27687707 |
| Li B et al. | Determination of antibacterial agent tilmicosin in pig plasma by LC/MS/MS and its application to pharmacokinetics. | 2017 | Biomed. Chromatogr. | pmid:27564248 |
| Prats-van der Ham M et al. | Molecular resistance mechanisms of Mycoplasma agalactiae to macrolides and lincomycin. | 2017 | Vet. Microbiol. | pmid:29102109 |
| Ray P et al. | Fate and Effect of Antibiotics in Beef and Dairy Manure during Static and Turned Composting. | 2017 | J. Environ. Qual. | pmid:28177414 |
| Qin Y et al. | Analysis of sulfonamides, tilmicosin and avermectins residues in typical animal matrices with multi-plug filtration cleanup by liquid chromatography-tandem mass spectrometry detection. | 2017 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:28410479 |
| Foster DM et al. | Comparison of direct sampling and brochoalveolar lavage for determining active drug concentrations in the pulmonary epithelial lining fluid of calves injected with enrofloxacin or tilmicosin. | 2017 | J. Vet. Pharmacol. Ther. | pmid:28457009 |
| Zhang L et al. | Pharmacokinetics of tilmicosin in healthy pigs and in pigs experimentally infected with . | 2017 | J. Vet. Sci. | pmid:28385011 |