| MeSH term | MeSH ID | Detail |
|---|---|---|
| Asthma | D001249 | 52 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Campylobacter Infections | D002169 | 13 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Conjunctivitis, Viral | D003236 | 1 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Dysentery | D004403 | 4 associated lipids |
| Enterotoxemia | D004767 | 1 associated lipids |
| Erysipelothrix Infections | D004889 | 1 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Keratoconjunctivitis, Infectious | D007639 | 2 associated lipids |
| Liver Abscess | D008100 | 6 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fajt VR et al. | The effects of danofloxacin and tilmicosin on neutrophil function and lung consolidation in beef heifer calves with induced Pasteurella (Mannheimia) haemolytica pneumonia. | 2003 | J. Vet. Pharmacol. Ther. | pmid:12755900 |
| Jordan FT et al. | A comparison of the efficacy of danofloxacin and tylosin in the control of Mycoplasma gallisepticum infection in broiler chicks. | 1993 | J. Vet. Pharmacol. Ther. | pmid:8386777 |
| Menge M et al. | Pharmacokinetics of tildipirosin in bovine plasma, lung tissue, and bronchial fluid (from live, nonanesthetized cattle). | 2012 | J. Vet. Pharmacol. Ther. | pmid:22188102 |
| Wang J et al. | Pharmacokinetics of tildipirosin in beagle dogs. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28892155 |
| Mohammadsadegh M | Impact of intramammary tilmicosin infusion as a dry cow therapy. | 2018 | J. Vet. Pharmacol. Ther. | pmid:28600854 |
| Han C et al. | Hydrogenated castor oil nanoparticles as carriers for the subcutaneous administration of tilmicosin: in vitro and in vivo studies. | 2009 | J. Vet. Pharmacol. Ther. | pmid:19290940 |
| Scorneaux B and Shryock TR | Intracellular accumulation, subcellular distribution and efflux of tilmicosin in swine phagocytes. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9731947 |
| Scorneaux B and Shryock TR | The determination of the cellular volume of avian, porcine and bovine phagocytes and bovine mammary epithelial cells and its relationship to uptake of tilmicosin. | 1999 | J. Vet. Pharmacol. Ther. | pmid:10211711 |
| Modric S et al. | Pharmacokinetics and pharmacodynamics of tilmicosin in sheep and cattle. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9885967 |
| Lee SW et al. | Prevalence of porcine proliferative enteropathy and its control with tylosin in Korea. | 2001 | J. Vet. Sci. | pmid:12441690 |
| Hwang YH et al. | Simultaneous determination of various macrolides by liquid chromatography/mass spectrometry. | 2002 | J. Vet. Sci. | pmid:12441679 |
| Kim D et al. | In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin. | 2006 | J. Vet. Sci. | pmid:17106227 |
| Zhang L et al. | Pharmacokinetics of tilmicosin in healthy pigs and in pigs experimentally infected with . | 2017 | J. Vet. Sci. | pmid:28385011 |
| Simpson EJ et al. | A simple method for the removal of mycoplasma contamination from paramyxovirus stocks. | 1983 | J. Virol. Methods | pmid:6190834 |
| Coronato S et al. | A simple method to eliminate mycoplasma from cell cultures. | 1994 | J. Virol. Methods | pmid:8175949 |
| Neiffer DL | Clostridium perfringens enterotoxicosis in two Amur leopards (Panthera pardus orientalis). | 2001 | J. Zoo Wildl. Med. | pmid:12790411 |
| Takahashi I et al. | [In vitro resistance acquisition in Mycoplasma gallisepticum against ofloxacin, tylosin and spectinomycin]. | 2002 | Jpn J Antibiot | pmid:12199113 |
| Diagnosis | pasteurellosis. | 2008 | Lab Anim (NY) | pmid:18094697 | |
| Modric S et al. | Effect of respiratory tract disease on pharmacokinetics of tilmicosin in rats. | 1999 | Lab. Anim. Sci. | pmid:10403438 |
| Mathieson PW et al. | Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis. | 1992 | Lab. Invest. | pmid:1625442 |