Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Asthma D001249 52 associated lipids
Ataxia D001259 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Bacteriuria D001437 7 associated lipids
Body Weight D001835 333 associated lipids
Campylobacter Infections D002169 13 associated lipids
Cattle Diseases D002418 24 associated lipids
Clostridium Infections D003015 5 associated lipids
Colitis D003092 69 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Diarrhea D003967 32 associated lipids
Dysentery D004403 4 associated lipids
Enterotoxemia D004767 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Facial Dermatoses D005148 7 associated lipids
Foreign Bodies D005547 5 associated lipids
Hemolysis D006461 131 associated lipids
Hyperplasia D006965 34 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Liver Abscess D008100 6 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Smith LK and Mankin AS Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. 2008 Antimicrob. Agents Chemother. pmid:18299405
Ayling RD et al. Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. 2005 Antimicrob. Agents Chemother. pmid:16304194
Chin AC et al. Tilmicosin induces apoptosis in bovine peripheral neutrophils in the presence or in the absence of Pasteurella haemolytica and promotes neutrophil phagocytosis by macrophages. 2000 Antimicrob. Agents Chemother. pmid:10952596
Dotzlaf JE et al. Incorporation of amino acid-derived carbon into tylactone by Streptomyces fradiae GS14. 1984 Antimicrob. Agents Chemother. pmid:6424562
Jost BH et al. Tylosin resistance in Arcanobacterium pyogenes is encoded by an erm X determinant. 2003 Antimicrob. Agents Chemother. pmid:14576111
Elkins CA and Mullis LB Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. 2007 Antimicrob. Agents Chemother. pmid:17210767
Shakya T and Wright GD Nucleotide selectivity of antibiotic kinases. 2010 Antimicrob. Agents Chemother. pmid:20231391
Hidalgo Á et al. Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain. 2011 Antimicrob. Agents Chemother. pmid:21555771
Huber ML et al. Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin. 1990 Antimicrob. Agents Chemother. pmid:2221862
Lin J et al. Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens. 2007 Antimicrob. Agents Chemother. pmid:17353243