Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Asthma D001249 52 associated lipids
Ataxia D001259 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Bacteriuria D001437 7 associated lipids
Body Weight D001835 333 associated lipids
Campylobacter Infections D002169 13 associated lipids
Cattle Diseases D002418 24 associated lipids
Clostridium Infections D003015 5 associated lipids
Colitis D003092 69 associated lipids
Conjunctivitis, Viral D003236 1 associated lipids
Diarrhea D003967 32 associated lipids
Dysentery D004403 4 associated lipids
Enterotoxemia D004767 1 associated lipids
Erysipelothrix Infections D004889 1 associated lipids
Facial Dermatoses D005148 7 associated lipids
Foreign Bodies D005547 5 associated lipids
Hemolysis D006461 131 associated lipids
Hyperplasia D006965 34 associated lipids
Keratoconjunctivitis, Infectious D007639 2 associated lipids
Liver Abscess D008100 6 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Gandecha AR et al. Analysis of four tylosin biosynthetic genes from the tylLM region of the Streptomyces fradiae genome. 1997 Gene pmid:9031628
Baltz RH et al. Applications of transposition mutagenesis in antibiotic producing streptomycetes. 1997 Antonie Van Leeuwenhoek pmid:9049029
McFarland JW et al. Repromicin derivatives with potent antibacterial activity against Pasteurella multocida. 1997 J. Med. Chem. pmid:9083494
McFarland JW et al. Quantitative structure-activity relationships among macrolide antibacterial agents: in vitro and in vivo potency against Pasteurella multocida. 1997 J. Med. Chem. pmid:9135031
Memili E and Weisblum B Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae. 1997 Antimicrob. Agents Chemother. pmid:9145902
Ramadan A Pharmacokinetics of tilmicosin in serum and milk of goats. 1997 Jan-Feb Res. Vet. Sci. pmid:9160424
Mironov VA et al. [Effect of Ca2+ ions on biosynthesis and component composition of tylosin in Streptomyces fradiae]. 1997 Antibiot. Khimioter. pmid:9182505
Morck DW et al. Treatment of experimentally induced pneumonic pasteurellosis of young calves with tilmicosin. 1997 Can. J. Vet. Res. pmid:9242998
Residues of some veterinary drugs in animals and foods. Monographs prepared by the Forty-Seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives. Rome, 4-13 June 1996. 1997 FAO Food Nutr Pap pmid:9253593
Naranda A et al. New dihydro and tetrahydro derivatives of desmycosin. III. The opening of oxirane ring of 12,13-epoxydesmycosin. 1997 J. Antibiot. pmid:9402992