Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Digital Dermatitis D058066 3 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Mycotoxicosis D015651 5 associated lipids
Weight Gain D015430 101 associated lipids
Vasculitis D014657 14 associated lipids
Treponemal Infections D014211 3 associated lipids
Tracheal Diseases D014133 3 associated lipids
Swine Diseases D013553 16 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pyoderma D011711 5 associated lipids
Per page 10 20 50 | Total 47

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Kim HB et al. Microbial shifts in the swine distal gut in response to the treatment with antimicrobial growth promoter, tylosin. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22955886
Malaiyandi V et al. Airborne allergic contact dermatitis from tylosin in pharmacy compounders and cross-sensitization to macrolide antibiotics. 2012 Sep-Oct Dermatitis pmid:23010831
Gaudin V et al. Validation of two ELISA kits for the screening of tylosin and streptomycin in honey according to the European decision 2002/657/EC. 2013 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:23013044
Devreese M et al. An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents. 2013 Toxicol In Vitro pmid:23078954
Del Pozo Sacristán R et al. Efficacy of in-feed medication with chlortetracycline in a farrow-to-finish herd against a clinical outbreak of respiratory disease in fattening pigs. 2012 Dec 22-29 Vet. Rec. pmid:23136309
Westermarck E and Wiberg M Exocrine pancreatic insufficiency in the dog: historical background, diagnosis, and treatment. 2012 Top Companion Anim Med pmid:23148848
Er A and Yazar E Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury. 2012 Acta Vet. Hung. pmid:23160029
Tsutsui A et al. Antimalarial C-9 oxime derivatives from desmycosin, produced by click chemistry. 2013 J. Antibiot. pmid:23232930
Burkin MA and Galvidis IA Hapten modification approach for switching immunoassay specificity from selective to generic. 2013 J. Immunol. Methods pmid:23234756
Fujiwara T et al. Absorption, tissue distribution and excretion of 19-deformyldesmycosin derivatives, new 16-membered macrolides, in mice. 1990 J. Antibiot. pmid:2324015
Hao H et al. Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. 2013 Antimicrob. Agents Chemother. pmid:23274667
Whitehead TR and Cotta MA Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. 2013 Lett. Appl. Microbiol. pmid:23297734
MiliavskiÄ­ EB et al. [Electrophoretic separation of spores of producers of kanamycin and tylosin]. 1990 Antibiot. Khimioter. pmid:2334246
Ali M et al. Effect of redox potential and pH status on degradation and adsorption behavior of tylosin in dairy lagoon sediment suspension. 2013 Chemosphere pmid:23352520
Holman DB and Chénier MR Impact of subtherapeutic administration of tylosin and chlortetracycline on antimicrobial resistance in farrow-to-finish swine. 2013 FEMS Microbiol. Ecol. pmid:23397987
Pinckney JL et al. Sublethal effects of the antibiotic tylosin on estuarine benthic microalgal communities. 2013 Mar. Pollut. Bull. pmid:23398744
Meyer NF et al. Effects of monensin and tylosin in finishing diets containing corn wet distillers grains with solubles with differing corn processing methods. 2013 J. Anim. Sci. pmid:23422007
Lin J et al. Response of intestinal microbiota to antibiotic growth promoters in chickens. 2013 Foodborne Pathog. Dis. pmid:23461609
Garcés-Narro C et al. Efficacy of low-dose tylvalosin for the control of clostridiosis in broilers and its effect on productive parameters. 2013 Poult. Sci. pmid:23472021
Pan R et al. Extraction of trace tilmicosin in real water samples using ionic liquid-based aqueous two-phase systems. 2013 Water Sci. Technol. pmid:23579819
Chopra S et al. Characterization of impurities in tylosin using dual liquid chromatography combined with ion trap mass spectrometry. 2013 Talanta pmid:23598092
Amachawadi RG et al. Occurrence of the transferable copper resistance gene tcrB among fecal enterococci of U.S. feedlot cattle fed copper-supplemented diets. 2013 Appl. Environ. Microbiol. pmid:23666328
Topp E et al. Accelerated Biodegradation of Veterinary Antibiotics in Agricultural Soil following Long-Term Exposure, and Isolation of a Sulfamethazine-degrading sp. J. Environ. Qual. pmid:23673752
Fujiwara T and Takenaka S Bioconversion of 19-deformyl-5-O-desosaminyl tylonolide to 19-deformyl-4'-deoxydesmycosin (TMC-016). 1990 FEMS Microbiol. Lett. pmid:2379808
Mitchell JD et al. In vitro pharmacodynamics of gamithromycin against Mycoplasma mycoides subspecies mycoides Small Colony. 2013 Vet. J. pmid:23810743
Panfilova ZI et al. [Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores]. 1990 Antibiot. Khimioter. pmid:2383150
Buß M et al. Quality control ranges for tylosin 30 μg and 15 μg discs applicable to Staphylococcus aureus ATCC(R) 25923. 2014 J. Antimicrob. Chemother. pmid:23928021
Svartström O et al. Characterization of Treponema spp. isolates from pigs with ear necrosis and shoulder ulcers. 2013 Vet. Microbiol. pmid:23948134
García-Sánchez L et al. Occurrence of tylosin in swine wastewater in Mexico. 2013 Water Sci. Technol. pmid:23985521
Zhang Q et al. Sorption of tylosin on clay minerals. 2013 Chemosphere pmid:24007614
Herd MB et al. Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. 2013 J. Neurosci. pmid:24027285
Corns SM et al. Development of antibiotic regimens using graph based evolutionary algorithms. 2013 BioSystems pmid:24051263
Kolanović BS et al. Tylosin content in meat and honey samples over a two-year period in Croatia. 2014 J Immunoassay Immunochem pmid:24063615
Stackhouse-Lawson KR et al. Growth promoting technologies reduce greenhouse gas, alcohol, and ammonia emissions from feedlot cattle. 2013 J. Anim. Sci. pmid:24085413
Shishkina A et al. Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel. 2013 Bioconjug. Chem. pmid:24090034
Mitchell SM et al. The effects of the antibiotics ampicillin, florfenicol, sulfamethazine, and tylosin on biogas production and their degradation efficiency during anaerobic digestion. 2013 Bioresour. Technol. pmid:24113548
Pilcher CM et al. Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. 2013 J. Anim. Sci. pmid:24126274
Guo X et al. The influences of pH and ionic strength on the sorption of tylosin on goethite. 2014 Environ Sci Pollut Res Int pmid:24197966
Pei Z et al. Effects of copper and aluminum on the adsorption of sulfathiazole and tylosin on peat and soil. 2014 Environ. Pollut. pmid:24201036
Amrine DE et al. Pulmonary lesions and clinical disease response to Mannheimia haemolytica challenge 10 days following administration of tildipirosin or tulathromycin. 2014 J. Anim. Sci. pmid:24243906
Kawai K et al. Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan. 2014 Anim. Sci. J. pmid:24261609
Khaliq S et al. Characterization of mutations in regulatory genes of Tyl cluster leading to overexpression of tylosin in mutant γ-1 of Streptomyces fradiae NRRL-2702. 2014 Appl. Microbiol. Biotechnol. pmid:24270892
Ji LW et al. Comparative pharmacokinetics and bioavailability of tylosin tartrate and tylosin phosphate after a single oral and i.v. administration in chickens. 2014 J. Vet. Pharmacol. Ther. pmid:24325541
Srinivasan P et al. Sorption of selected veterinary antibiotics onto dairy farming soils of contrasting nature. 2014 Sci. Total Environ. pmid:24326064
Lerner U et al. Acquired resistance to the 16-membered macrolides tylosin and tilmicosin by Mycoplasma bovis. 2014 Vet. Microbiol. pmid:24393633
Entorf M et al. Tylosin susceptibility of Staphylococci from bovine mastitis. 2014 Vet. Microbiol. pmid:24461550
Marosevic D et al. In vivo spread of macrolide-lincosamide-streptogramin B (MLSB) resistance--a model study in chickens. 2014 Vet. Microbiol. pmid:24467930
Beck P et al. Additive effects of growth promoting technologies on performance of grazing steers and economics of the wheat pasture enterprise. 2014 J. Anim. Sci. pmid:24492552
Ferrag-Siagh F et al. Electro-Fenton pretreatment for the improvement of tylosin biodegradability. 2014 Environ Sci Pollut Res Int pmid:24705893
Kim HB et al. Effects of tylosin administration on C-reactive protein concentration and carriage of Salmonella enterica in pigs. 2014 Am. J. Vet. Res. pmid:24762018