Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Fu H et al. | Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16343900 |
Chelliapan S et al. | Performance of an up-flow anaerobic stage reactor (UASR) in the treatment of pharmaceutical wastewater containing macrolide antibiotics. | 2006 | Water Res. | pmid:16387347 |
Jacobsen AM and Halling-Sørensen B | Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. | 2006 | Anal Bioanal Chem | pmid:16485090 |
Jung WS et al. | Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16493552 |
Carlson JC and Mabury SA | Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. | 2006 | Environ. Toxicol. Chem. | pmid:16494218 |
Womble A et al. | Pulmonary disposition of tilmicosin in foals and in vitro activity against Rhodococcus equi and other common equine bacterial pathogens. | 2006 | J. Vet. Pharmacol. Ther. | pmid:17083461 |
Booker CW et al. | An evaluation of the metaphylactic effect of ceftiofur crystalline free Acid in feedlot calves. | 2006 | Vet. Ther. | pmid:17039449 |
Karahalios P et al. | On the mechanism of action of 9-O-arylalkyloxime derivatives of 6-O-mycaminosyltylonolide, a new class of 16-membered macrolide antibiotics. | 2006 | Mol. Pharmacol. | pmid:16873579 |
Hamscher G et al. | Quantitative analysis of tylosin in eggs by high performance liquid chromatography with electrospray ionization tandem mass spectrometry: residue depletion kinetics after administration via feed and drinking water in laying hens. | 2006 | J. Agric. Food Chem. | pmid:17117786 |
Veenhuizen MF et al. | Analysis of reports of human exposure to Micotil 300 (tilmicosin injection). | 2006 | J. Am. Vet. Med. Assoc. | pmid:17144818 |
Couper A et al. | Treatment of pneumonia in pigs with long-acting injectable tylosin. | 2006 | Vet. Rec. | pmid:17158711 |
Chun S et al. | Influence of agricultural antibiotics and 17beta-estradiol on the microbial community of soil. | 2006 | J Environ Sci Health B | pmid:16893780 |
Nozal Nalda MJ et al. | Trace analysis of antibacterial tylosin A, B, C and D in honey by liquid chromatography-electrospray ionization-mass spectrometry. | 2006 | J Sep Sci | pmid:16544883 |
Cao XY et al. | Tilmicosin and tylosin have anti-inflammatory properties via modulation of COX-2 and iNOS gene expression and production of cytokines in LPS-induced macrophages and monocytes. | 2006 | Int. J. Antimicrob. Agents | pmid:16647840 |
Dingwell RT et al. | Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. | 2006 | Can. J. Vet. Res. | pmid:16639943 |
ter Laak TL et al. | The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. | 2006 | Environ. Toxicol. Chem. | pmid:16629129 |
ter Laak TL et al. | Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. | 2006 | Environ. Toxicol. Chem. | pmid:16629132 |
Terui Y et al. | Synthesis of 2-methyl 16-membered macrolide derived from tylosin. | 2006 | J. Antibiot. | pmid:16629410 |
Jiang H et al. | Residue depletion of tilmicosin in cattle after subcutaneous administration. | 2006 | J. Agric. Food Chem. | pmid:16819937 |
Yang S et al. | Trace analysis and occurrence of anhydroerythromycin and tylosin in influent and effluent wastewater by liquid chromatography combined with electrospray tandem mass spectrometry. | 2006 | Anal Bioanal Chem | pmid:16715282 |
GarcÃa-Mayor MA et al. | Liquid chromatography-UV diode-array detection method for multi-residue determination of macrolide antibiotics in sheep's milk. | 2006 | J Chromatogr A | pmid:16682049 |
Shakeri-Nejad K and Stahlmann R | Drug interactions during therapy with three major groups of antimicrobial agents. | 2006 | Expert Opin Pharmacother | pmid:16556082 |
Kim D et al. | In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin. | 2006 | J. Vet. Sci. | pmid:17106227 |
Allaire SE et al. | Sorption kinetics of chlortetracyline and tylosin on sandy loam and heavy clay soils. | 2006 Jul-Aug | J. Environ. Qual. | pmid:16738380 |
Sassman SA et al. | Sorption of tylosin A, D, and A-aldol and degradation of tylosin A in soils. | 2007 | Environ. Toxicol. Chem. | pmid:17702335 |
Ladely SR et al. | Development of macrolide-resistant Campylobacter in broilers administered subtherapeutic or therapeutic concentrations of tylosin. | 2007 | J. Food Prot. | pmid:17803155 |
MartÃnez MF and Barth AD | Early detection and treatment of vesicular adenitis in bulls. | 2007 | Anim. Reprod. Sci. | pmid:17027202 |
Lüthje P and Schwarz S | Molecular analysis of constitutively expressed erm(C) genes selected in vitro in the presence of the non-inducers pirlimycin, spiramycin and tylosin. | 2007 | J. Antimicrob. Chemother. | pmid:17085767 |
Szczepanowski R et al. | Novel macrolide resistance module carried by the IncP-1beta resistance plasmid pRSB111, isolated from a wastewater treatment plant. | 2007 | Antimicrob. Agents Chemother. | pmid:17101677 |
Bignell DR et al. | Regulation of tylosin production: role of a TylP-interactive ligand. | 2007 | Mol. Microbiol. | pmid:17181783 |
Abu-Basha EA et al. | Pharmacokinetics of tilmicosin (Provitil powder and Pulmotil liquid AC) oral formulations in chickens. | 2007 | Vet. Res. Commun. | pmid:17225089 |
McDougall S et al. | Parenteral treatment of clinical mastitis with tylosin base or penethamate hydriodide in dairy cattle. | 2007 | J. Dairy Sci. | pmid:17235155 |
Blackwell PA et al. | The dissipation and transport of veterinary antibiotics in a sandy loam soil. | 2007 | Chemosphere | pmid:17204303 |
Elkins CA and Mullis LB | Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. | 2007 | Antimicrob. Agents Chemother. | pmid:17210767 |
Booker CW et al. | Evaluation of the efficacy of tulathromycin as a metaphylactic antimicrobial in feedlot calves. | 2007 | Vet. Ther. | pmid:17926304 |
Boissevain I | [Punishment after the fact]. | 2007 | Tijdschr Diergeneeskd | pmid:17939495 |
González de la Huebra MJ et al. | Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD). | 2007 | J Pharm Biomed Anal | pmid:17257795 |
Kart A et al. | The possible protective effect of L-carnitine on tilmicosin-induced cardiotoxicity in mice. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17381679 |
Lin J et al. | Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens. | 2007 | Antimicrob. Agents Chemother. | pmid:17353243 |
Litterio NJ et al. | Microbiological screening test validation for detection of tylosin excretion in milk of cows with low and high somatic cell counts. | 2007 | J Vet Med A Physiol Pathol Clin Med | pmid:17359452 |
Thompson TS et al. | Degradation of incurred tylosin to desmycosin--implications for residue analysis of honey. | 2007 | Anal. Chim. Acta | pmid:17386728 |
Hu D and Coats JR | Aerobic degradation and photolysis of tylosin in water and soil. | 2007 | Environ. Toxicol. Chem. | pmid:17521133 |
Song W et al. | Determination of amprolium, carbadox, monensin, and tylosin in surface water by liquid chromatography/tandem mass spectrometry. | 2007 | Rapid Commun. Mass Spectrom. | pmid:17510929 |
Vincent U et al. | Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. | 2007 | Food Addit Contam | pmid:17454108 |
Berrang ME et al. | Subtherapeutic tylosin phosphate in broiler feed affects Campylobacter on carcasses during processing. | 2007 | Poult. Sci. | pmid:17495097 |
Herrera M et al. | Quantitative determination of tilmicosin in canine serum by high performance liquid chromatography-tandem mass spectrometry. | 2007 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:17627909 |
Xie W et al. | [Determination of five macrolide antibiotic residues in royal jelly samples by using high performance liquid chromatography tandem mass spectrometry]. | 2007 | Se Pu | pmid:17679440 |
Werner JJ et al. | Environmental photochemistry of tylosin: efficient, reversible photoisomerization to a less-active isomer, followed by photolysis. | 2007 | J. Agric. Food Chem. | pmid:17655244 |
Antunes NT et al. | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. | 2007 | Antimicrob. Agents Chemother. | pmid:17638695 |
Nagaraja TG and Lechtenberg KF | Liver abscesses in feedlot cattle. | 2007 | Vet. Clin. North Am. Food Anim. Pract. | pmid:17606156 |