Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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DENNY CB et al. | Effects of tylosin and nisin on canned food spoilage bacteria. | 1961 | Appl Microbiol | pmid:13721908 |
Arzey GG and Arzey KE | Successful treatment of mycoplasmosis in layer chickens with single dose therapy. | 1992 | Aust. Vet. J. | pmid:1379426 |
Brahimi-Horn MC et al. | Synthesis of hydrolytic enzymes during production of tylosin by Streptomyces fradiae. | 1992 | J. Ind. Microbiol. | pmid:1381591 |
Kádár-Pauncz J et al. | Isolation and structure elucidation of new antibiotics related to angolamycin. | 1992 | J. Antibiot. | pmid:1399843 |
Gummow B et al. | The diagnosis and treatment of bovine genital ureaplasmosis: a case study. | 1992 | J S Afr Vet Assoc | pmid:1404223 |
Chin NX and Neu HC | In vitro activity of MC-352, a new 16-membered macrolide. | 1992 | Antimicrob. Agents Chemother. | pmid:1416853 |
Galyean ML et al. | Performance of feedlot steers fed diets containing laidlomycin propionate or monensin plus tylosin, and effects of laidlomycin propionate concentration on intake patterns and ruminal fermentation in beef steers during adaptation to a high-concentrate diet. | 1992 | J. Anim. Sci. | pmid:1429270 |
DOORNENBAL H | CLINICAL EVALUATION OF TYLOSIN AS A TREATMENT OF VIBRIONIC DYSENTERY IN SWINE. | 1965 | Can J Comp Med Vet Sci | pmid:14300858 |
Collier CT et al. | Effects of tylosin on bacterial mucolysis, Clostridium perfringens colonization, and intestinal barrier function in a chick model of necrotic enteritis. | 2003 | Antimicrob. Agents Chemother. | pmid:14506046 |
Chuard C et al. | In-vitro and in-vivo evaluation of the antistaphylococcal activity of S-5556, a new 16-membered macrolide. | 1992 | J. Antimicrob. Chemother. | pmid:1452498 |