Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Angell JW et al. | Whole-flock, metaphylactic tilmicosin failed to eliminate contagious ovine digital dermatitis and footrot in sheep: a cluster randomised trial. | 2016 | Vet. Rec. | pmid:27450091 |
Henderson JP and Ball HJ | Polyarthritis due to Mycoplasma bovis infection in adult dairy cattle in Northern Ireland. | 1999 | Vet. Rec. | pmid:10573196 |
Ayling RD et al. | Comparison of in vitro activity of danofloxacin, florfenicol, oxytetracycline, spectinomycin and tilmicosin against Mycoplasma mycoides subspecies mycoides small colony type. | 2000 | Vet. Rec. | pmid:10737293 |
Vicca J et al. | Efficacy of in-feed medication with tylosin for the treatment and control of Mycoplasma hyopneumoniae infections. | 2005 | Vet. Rec. | pmid:15879541 |
Ayling RD et al. | Comparison of in vitro activity of danofloxacin, florfenicol, oxytetracycline, spectinomycin and tilmicosin against recent field isolates of Mycoplasma bovis. | 2000 | Vet. Rec. | pmid:10909906 |
Couper A et al. | Treatment of pneumonia in pigs with long-acting injectable tylosin. | 2006 | Vet. Rec. | pmid:17158711 |
Lawrence K | Change to user warning for Micotil. | 2004 | Vet. Rec. | pmid:15200081 |
Mackinnon JD et al. | Effect of tylosin on milk yield and dry matter intake of lactating dairy cows. | 1984 | Vet. Rec. | pmid:6495581 |
Giadinis ND et al. | Mortality in adult goats attributed to Mycoplasma capricolum subspecies capricolum. | 2008 | Vet. Rec. | pmid:18757908 |
Del Pozo Sacristán R et al. | Efficacy of in-feed medication with chlortetracycline in a farrow-to-finish herd against a clinical outbreak of respiratory disease in fattening pigs. | 2012 Dec 22-29 | Vet. Rec. | pmid:23136309 |
Rowan TG et al. | Efficacy of danofloxacin in the treatment of respiratory disease in European cattle. | 2004 | Vet. Rec. | pmid:15160844 |
Picavet T et al. | Efficacy of tilmicosin in treatment of pulmonary infections in calves. | 1991 | Vet. Rec. | pmid:1837391 |
Ball HJ and McCaughey WJ | Experimental intramuscular inoculation of tylosin in the elimination of ureaplasmas from ewes. | 1987 | Vet. Rec. | pmid:3617407 |
Ose EE and Tonkinson LV | Single-dose treatment of neonatal calf pneumonia with the new macrolide antibiotic tilmicosin. | 1988 | Vet. Rec. | pmid:3195026 |
Paraud C et al. | Evaluation of oral tilmicosin efficacy against severe cryptosporidiosis in neonatal kids under field conditions. | 2010 | Vet. Parasitol. | pmid:20149542 |
Marks SL and Kather EJ | Antimicrobial susceptibilities of canine Clostridium difficile and Clostridium perfringens isolates to commonly utilized antimicrobial drugs. | 2003 | Vet. Microbiol. | pmid:12742714 |
Alippi AM et al. | In vitro and in vivo susceptibility of the honeybee bacterial pathogen Paenibacillus larvae subsp. larvae to the antibiotic tylosin. | 2005 | Vet. Microbiol. | pmid:15951140 |
Juntunen P et al. | Antimicrobial resistance in Campylobacter coli selected by tylosin treatment at a pig farm. | 2010 | Vet. Microbiol. | pmid:20684867 |
Cornick NA | Tylosin and chlorotetracycline decrease the duration of fecal shedding of E. coli O157:H7 by swine. | 2010 | Vet. Microbiol. | pmid:20018464 |
Aarestrup FM and Jensen NE | Susceptibility testing of Actinobacillus pleuropneumoniae in Denmark. Evaluation of three different media of MIC-determinations and tablet diffusion tests. | 1999 | Vet. Microbiol. | pmid:10063535 |