Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhang B et al. | The effects of bio-available copper on macrolide antibiotic resistance genes and mobile elements during tylosin fermentation dregs co-composting. | 2018 | Bioresour. Technol. | pmid:29278844 |
| Stone JJ et al. | Tylosin and chlortetracycline effects during swine manure digestion: influence of sodium azide. | 2010 | Bioresour. Technol. | pmid:20728345 |
| Mitchell SM et al. | The effects of the antibiotics ampicillin, florfenicol, sulfamethazine, and tylosin on biogas production and their degradation efficiency during anaerobic digestion. | 2013 | Bioresour. Technol. | pmid:24113548 |
| Choi DB et al. | Effects of rapessed oil on activity of methylmalonyl-CoA carboxyltransferase in culture of Streptomyces fradiae. | 1998 | Biosci. Biotechnol. Biochem. | pmid:9648221 |
| Arisawa A et al. | Cloning and nucleotide sequences of two genes involved in the 4''-O-acylation of macrolide antibiotics from Streptomyces thermotolerans. | 1993 | Biosci. Biotechnol. Biochem. | pmid:7764361 |
| Corns SM et al. | Development of antibiotic regimens using graph based evolutionary algorithms. | 2013 | BioSystems | pmid:24051263 |
| Shimada T et al. | Inhibitory effects of the macrolide antimicrobial tylosin on anaerobic treatment. | 2008 | Biotechnol. Bioeng. | pmid:18646223 |
| Shimada T et al. | Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor. | 2011 | Biotechnol. Bioeng. | pmid:20830676 |
| Vaidyanathan S et al. | Assessment of near-infrared spectral information for rapid monitoring of bioprocess quality. | 2001 | Biotechnol. Bioeng. | pmid:11427939 |
| Alexander TW et al. | Longitudinal characterization of antimicrobial resistance genes in feces shed from cattle fed different subtherapeutic antibiotics. | 2011 | BMC Microbiol. | pmid:21261985 |
| Suchodolski JS et al. | The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. | 2009 | BMC Microbiol. | pmid:19799792 |
| Berman J et al. | A randomised clinical trial of a metaphylactic treatment with tildipirosin for bovine respiratory disease in veal calves. | 2017 | BMC Vet. Res. | pmid:28615070 |
| Kreizinger Z et al. | Antibiotic susceptibility profiles of Mycoplasma synoviae strains originating from Central and Eastern Europe. | 2017 | BMC Vet. Res. | pmid:29149886 |
| Qekwana DN et al. | Patterns and predictors of antimicrobial resistance among Staphylococcus spp. from canine clinical cases presented at a veterinary academic hospital in South Africa. | 2017 | BMC Vet. Res. | pmid:28454567 |
| Li Y et al. | In vitro susceptibility of four antimicrobials against Riemerella anatipestifer isolates: a comparison of minimum inhibitory concentrations and mutant prevention concentrations for ceftiofur, cefquinome, florfenicol, and tilmicosin. | 2016 | BMC Vet. Res. | pmid:27829415 |
| Huang L et al. | Pharmacokinetic-pharmacodynamic modeling of tylosin against Streptococcus suis in pigs. | 2018 | BMC Vet. Res. | pmid:30355326 |
| Pedersen KB | Some growth promoters in animals do confer antimicrobial resistance in humans. | 1999 | BMJ | pmid:10205122 |
| Gollins WJ | Occupational asthma due to tylosin tartrate. | 1989 | Br J Ind Med | pmid:2611166 |
| Lee HS et al. | Occupational asthma due to tylosin tartrate. | 1989 | Br J Ind Med | pmid:2765423 |
| Gyémánt N et al. | In vitro and in vivo multidrug resistance reversal activity by a Betti-base derivative of tylosin. | 2010 | Br. J. Cancer | pmid:20551959 |
| Collington GK et al. | The influence of inclusion of either an antibiotic or a probiotic in the diet on the development of digestive enzyme activity in the pig. | 1990 | Br. J. Nutr. | pmid:2119223 |
| Lilia G et al. | Circadian serum concentrations of tylosin in broilers after feed or water medication. | 2008 | Br. Poult. Sci. | pmid:18836909 |
| Roudaut B and Moretain JP | Residues of macrolide antibiotics in eggs following medication of laying hens. | 1990 | Br. Poult. Sci. | pmid:2245358 |
| Hunter RP et al. | Letter to the editor. | 2009 | Br. Poult. Sci. | pmid:19904632 |
| Scott PR | Efficacy of strategic tilmicosin injection during an outbreak of respiratory disease in housed beef calves. | 1995 Sep-Oct | Br. Vet. J. | pmid:8556318 |
| Atef M et al. | Disposition of tylosin in goats. | 1991 May-Jun | Br. Vet. J. | pmid:1878767 |
| Kim HY et al. | Biochemical effects of veterinary antibiotics on proliferation and cell cycle arrest of human HEK293 cells. | 2012 | Bull Environ Contam Toxicol | pmid:22673765 |
| DOORNENBAL H | CLINICAL EVALUATION OF TYLOSIN AS A TREATMENT OF VIBRIONIC DYSENTERY IN SWINE. | 1965 | Can J Comp Med Vet Sci | pmid:14300858 |
| Truscott RB and Ruhnke HL | The effect of antibiotics against bovine mycoplasmas and ureaplasmas. | 1984 | Can. J. Comp. Med. | pmid:6232992 |
| Truscott RB | Factors associated with the determination of antibiotic activity in bovine semen. | 1983 | Can. J. Comp. Med. | pmid:6230144 |
| Abdel-Daim MM et al. | Synergistic protective role of mirazid (Commiphora molmol) and ascorbic acid against tilmicosin-induced cardiotoxicity in mice. | 2015 | Can. J. Physiol. Pharmacol. | pmid:25429612 |
| Paradis MA et al. | Efficacy of tilmicosin in the control of experimentally induced Actinobacillus pleuropneumoniae infection in swine. | 2004 | Can. J. Vet. Res. | pmid:14979429 |
| Fittipaldi N et al. | Assessment of the efficacy of tilmicosin phosphate to eliminate Actinobacillus pleuropneumoniae from carrier pigs. | 2005 | Can. J. Vet. Res. | pmid:15971680 |
| Goubau S et al. | Tilmicosin does not inhibit interleukin-8 gene expression in the bovine lung experimentally infected with Mannheimia (Pasteurella) haemolytica. | 2000 | Can. J. Vet. Res. | pmid:11041503 |
| Dingwell RT et al. | Influence of the genotype of Staphylococcus aureus, determined by pulsed-field gel electrophoresis, on dry-period elimination of subclinical mastitis in Canadian dairy herds. | 2006 | Can. J. Vet. Res. | pmid:16639943 |
| Brumbaugh GW et al. | Susceptibility of Mycobacterium avium sbsp paratuberculosis to monensin sodium or tilmicosin phosphate in vitro and resulting infectivity in a murine model. | 2004 | Can. J. Vet. Res. | pmid:15352541 |
| Morck DW et al. | Treatment of experimentally induced pneumonic pasteurellosis of young calves with tilmicosin. | 1997 | Can. J. Vet. Res. | pmid:9242998 |
| Buret AG | Immuno-modulation and anti-inflammatory benefits of antibiotics: the example of tilmicosin. | 2010 | Can. J. Vet. Res. | pmid:20357951 |
| Burrows GE et al. | Antibiotic disposition in experimental pneumonic pasteurellosis: gentamicin and tylosin. | 1986 | Can. J. Vet. Res. | pmid:3756673 |
| Scott DW et al. | Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1994 | Can. Vet. J. | pmid:7994702 |
| Van Lunen TA | Growth performance of pigs fed diets with and without tylosin phosphate supplementation and reared in a biosecure all-in all-out housing system. | 2003 | Can. Vet. J. | pmid:12892287 |
| Croft A et al. | The effect of tilmicosin administered to ewes prior to lambing on incidence of clinical mastitis and subsequent lamb performance. | 2000 | Can. Vet. J. | pmid:10769768 |
| Van Donkersgoed J et al. | The effect of administering long-acting oxytetracycline and tilmicosin either by dart gun or by hand on injection site lesions and drug residues in beef cattle. | 1999 | Can. Vet. J. | pmid:12001341 |
| Schunich OC et al. | A comparison of prophylactic efficacy of tilmicosin and a new formulation of oxytetracycline in feedlot calves. | 2002 | Can. Vet. J. | pmid:12001501 |
| Abutarbush SM et al. | Comparison of enrofloxacin and ceftiofur sodium for the treatment of relapse of undifferentiated fever/bovine respiratory disease in feedlot cattle. | 2012 | Can. Vet. J. | pmid:22753964 |
| Scott DW et al. | Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1996 | Can. Vet. J. | pmid:8896878 |
| Christodoulopoulos G | Adverse outcome of using tilmicosin in a lamb with multiple ventricular septal defects. | 2009 | Can. Vet. J. | pmid:19337615 |
| Hoar BR et al. | A comparison of the clinical field efficacy and safety of florfenicol and tilmicosin for the treatment of undifferentiated bovine respiratory disease of cattle in western Canada. | 1998 | Can. Vet. J. | pmid:9524721 |
| Barth AD and Wood MR | The effect of streptomycin, oxytetracycline, tilmicosin and phenylbutazone on spermatogenesis in bulls. | 1998 | Can. Vet. J. | pmid:10051958 |
| Jim GK et al. | A comparison of florfenicol and tilmicosin for the treatment of undifferentiated fever in feedlot calves in western Canada. | 1999 | Can. Vet. J. | pmid:10086218 |