Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Gershon P and Howells RE | Synergy of four macrolide antibiotics with chloroquine against chloroquine-resistant Plasmodium falciparum in vitro. | 1986 | Trans. R. Soc. Trop. Med. Hyg. | pmid:3299891 |
Moats WA | Effect of the silica support of bonded reversed-phase columns on chromatography of some antibiotic compounds. | 1986 | J. Chromatogr. | pmid:3023412 |
Moats WA | Chromatographic methods for determination of macrolide antibiotic residues in tissues and milk of food-producing animals. | 1985 Sep-Oct | J Assoc Off Anal Chem | pmid:4055648 |
Moats WA et al. | Comparison of liquid chromatographic and bioassay procedures for determining depletion of intramuscularly injected tylosin. | 1985 May-Jun | J Assoc Off Anal Chem | pmid:4019360 |
Goodwin RF | In vitro activity of tiamulin against porcine mycoplasmas. | 1985 | Res. Vet. Sci. | pmid:3975477 |
Kietzmann M | [Comparative study of the distribution and excretion of tylosin of various origins]. | 1985 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:3899580 |
Itoh Z et al. | Structure-activity relation among macrolide antibiotics in initiation of interdigestive migrating contractions in the canine gastrointestinal tract. | 1985 | Am. J. Physiol. | pmid:3976891 |
Brumm MC and Peo ER | Effect of receiving diets containing alfalfa and certain feed additives on performance of feeder pigs transported long distances. | 1985 | J. Anim. Sci. | pmid:4030523 |
Tejedor F and Ballesta JP | Components of the macrolide binding site on the ribosome. | 1985 | J. Antimicrob. Chemother. | pmid:4055551 |
Baltz RH and Stonesifer J | Phenotypic changes associated with loss of expression of tylosin biosynthesis and resistance genes in Streptomyces fradiae. | 1985 | J. Antibiot. | pmid:4066505 |
Duthu GS | Interspecies correlation of the pharmacokinetics of erythromycin, oleandomycin, and tylosin. | 1985 | J Pharm Sci | pmid:4067847 |
Potter EL et al. | Effect of monensin and tylosin on average daily gain, feed efficiency and liver abscess incidence in feedlot cattle. | 1985 | J. Anim. Sci. | pmid:4077750 |
Wayner EA and Brooks CG | Induction of NKCF-like activity in mixed lymphocyte-tumor cell culture: direct involvement of mycoplasma infection of tumor cells. | 1984 | J. Immunol. | pmid:6230401 |
Truscott RB and Ruhnke HL | The effect of antibiotics against bovine mycoplasmas and ureaplasmas. | 1984 | Can. J. Comp. Med. | pmid:6232992 |
Stipkovits L et al. | Efficacy of lasalocid sodium against mycoplasmas (preliminary communication). | 1984 | Acta Vet. Hung. | pmid:6242271 |
Omura S et al. | Ammonium ions suppress the amino acid metabolism involved in the biosynthesis of protylonolide in a mutant of Streptomyces fradiae. | 1984 | J. Antibiot. | pmid:6511663 |
Mackinnon JD et al. | Effect of tylosin on milk yield and dry matter intake of lactating dairy cows. | 1984 | Vet. Rec. | pmid:6495581 |
Omura S et al. | Chemical modification of tylosin. Thioether derivatives of tylosin and demycarosyltylosin. | 1984 | J. Antibiot. | pmid:6501102 |
Dilov P et al. | [Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs]. | 1984 | Vet Med Nauki | pmid:6474828 |
Omura S et al. | Effect of ammonium ion, inorganic phosphate and amino acids on the biosynthesis of protylonolide, a precursor of tylosin aglycone. | 1984 | J. Antibiot. | pmid:6735923 |