Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Lee SH Ammonium ion affecting tylosin production by Streptomyces fradiae NRRL 2702 in continuous culture. 1997 Lett. Appl. Microbiol. pmid:9418071
Readnour RS et al. Liquid chromatographic determination of tilmicosin in swine feed at 200-400 mg/kg level: interlaboratory study. 1997 Nov-Dec J AOAC Int pmid:9419853
Readnour RS et al. Determination of tilmicosin in swine feeds by liquid chromatography. 1997 Nov-Dec J AOAC Int pmid:9419854
Moran JW et al. Determination of tilmicosin in bovine and porcine sera by liquid chromatography. 1997 Nov-Dec J AOAC Int pmid:9419857
Fish SA and Cundliffe E Stimulation of polyketide metabolism in Streptomyces fradiae by tylosin and its glycosylated precursors. 1997 Microbiology (Reading, Engl.) pmid:9421911
Yeh WK Evolving enzyme technology for pharmaceutical applications: case studies. 1997 Nov-Dec J. Ind. Microbiol. Biotechnol. pmid:9451830
Kempf I et al. Efficacy of tilmicosin in the control of experimental Mycoplasma gallisepticum infection in chickens. 1997 Oct-Dec Avian Dis. pmid:9454912
Nagaraja TG and Chengappa MM Liver abscesses in feedlot cattle: a review. 1998 J. Anim. Sci. pmid:9464910
Hoar BR et al. A comparison of the clinical field efficacy and safety of florfenicol and tilmicosin for the treatment of undifferentiated bovine respiratory disease of cattle in western Canada. 1998 Can. Vet. J. pmid:9524721
Norcia LJ et al. In vitro microbiological characterization of novel macrolide CP-163,505 for animal health specific use. 1998 J. Antibiot. pmid:9544934
Tsinas AC et al. Control of proliferative enteropathy in growing/fattening pigs using growth promoters. 1998 Zentralblatt Veterinarmedizin Reihe B pmid:9557133
Esipov SE [Novel mathematical approach to determination of antibiotics concentration by agar diffusion method. Analysis of graphical, table and mathematical options of relative biological activity estimation]. 1998 Antibiot. Khimioter. pmid:9606490
Vogel GJ et al. Effects of tilmicosin on acute undifferentiated respiratory tract disease in newly arrived feedlot cattle. 1998 J. Am. Vet. Med. Assoc. pmid:9638194
Aarestrup FM and Friis NF Antimicrobial susceptibility testing of Mycoplasma hyosynoviae isolated from pigs during 1968 to 1971 and during 1995 and 1996. 1998 Vet. Microbiol. pmid:9646463
Shryock TR et al. Antimicrobial susceptibility of Moraxella bovis. 1998 Vet. Microbiol. pmid:9646479
Choi DB et al. Effects of rapessed oil on activity of methylmalonyl-CoA carboxyltransferase in culture of Streptomyces fradiae. 1998 Biosci. Biotechnol. Biochem. pmid:9648221
Wilson VT and Cundliffe E Characterization and targeted disruption of a glycosyltransferase gene in the tylosin producer, Streptomyces fradiae. 1998 Gene pmid:9651492
Baba T et al. Effect of tylosin tartrate on humoral immune responses in chickens. 1998 Zentralblatt Veterinarmedizin Reihe B pmid:9673579
Beharka AA and Nagaraja TG Effect of Aspergillus oryzae extract alone or in combination with antimicrobial compounds on ruminal bacteria. 1998 J. Dairy Sci. pmid:9684165
Gotoh Y et al. Chemical transformation of tylosin derivatives into neutral macrolides having a 3'-methoxyl group. 1998 Carbohydr. Res. pmid:9720235
Scorneaux B and Shryock TR Intracellular accumulation, subcellular distribution and efflux of tilmicosin in swine phagocytes. 1998 J. Vet. Pharmacol. Ther. pmid:9731947
Grdisa M et al. Effect of a 17-member azalide on tumor cell growth. 1998 Sep-Oct Chemotherapy pmid:9732149
Baba T et al. Effect of tylosin tartrate (Tylan Soluble) on cellular immune responses in chickens. 1998 Poult. Sci. pmid:9733118
De Liguoro M et al. Determination of tylosin residues in pig tissues using high-performance liquid chromatography. 1998 Analyst pmid:9764508
Berque I et al. [Stereoselective synthesis of biologically active macrolides. Total synthesis of tylosine]. 1998 Ann Pharm Fr pmid:9770007
Scorneaux B and Shryock TR Intracellular accumulation, subcellular distribution, and efflux of tilmicosin in chicken phagocytes. 1998 Poult. Sci. pmid:9776059
Oh TG et al. Induction of ermAMR from a clinical strain of Enterococcus faecalis by 16-membered-ring macrolide antibiotics. 1998 J. Bacteriol. pmid:9791136
Koenen-Dierick K and De Beer JO Optimization of an antibiotic residue screening test, based on inhibition of Bacillus subtilis BGA, with experimental design. 1998 Food Addit Contam pmid:9829036
Jordan FT et al. In vitro and in vivo comparisons of valnemulin, tiamulin, tylosin, enrofloxacin, and lincomycin/spectinomycin against Mycoplasma gallisepticum. 1998 Oct-Dec Avian Dis. pmid:9876842
Modric S et al. Pharmacokinetics and pharmacodynamics of tilmicosin in sheep and cattle. 1998 J. Vet. Pharmacol. Ther. pmid:9885967
Aarestrup FM and Carstensen B Effect of tylosin used as a growth promoter on the occurrence of macrolide-resistant enterococci and staphylococci in pigs. 1998 Microb. Drug Resist. pmid:9988049